Výsledky vyhledávání - "Katarzyna Brzezniakiewicz"

Extracellular Adenosine (eAdo) - A2B Receptor Axis Inhibits in Nlrp3 Inflammasome-dependent Manner Trafficking of Hematopoietic Stem/progenitor Cells

Autor: Arjun Thapa, Ahmed Abdelbaset-Ismail, Vira Chumak, Mateusz Adamiak, Katarzyna Brzezniakiewicz-Janus, Janina Ratajczak, Magdalena Kucia, Mariusz Z. Ratajczak

Publikováno v: Stem Cell Reviews and Reports. 18:2893-2911

We postulated that mobilization, homing, and engraftment of hematopoietic stem/progenitor cells (HSCPs) is facilitated by a state of sterile inflammation induced in bone marrow (BM) after administration of pro-mobilizing drugs or in response to pre-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ff17250da8bdc2ce97af4723b0cae6
https://doi.org/10.1007/s12015-022-10417-w

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Akademický článek

The Complement Cascade as a Mediator of Human Malignant Hematopoietic Cell Trafficking

Autor: Anna Lenkiewicz, Kamila Bujko, Katarzyna Brzezniakiewicz-Janus, Bing Xu, Mariusz Z. Ratajczak

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

The complement cascade (ComC) cleavage fragments C3a and C5a regulate the trafficking of normal, differentiated hematopoietic cells, although they do not chemoattract more primitive hematopoietic stem/progenitor cells (HSPCs). By contrast, human myel

Externí odkaz: https://doaj.org/article/dc63b09369b54756a76a46ea2c074943

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Akademický článek

The Effect of Radiotherapy on the Concentration of Plasma Lipids in Elderly Prostate Cancer Patients

Autor: Edyta Wolny-Rokicka, Andrzej Tukiendorf, Jerzy Wydmański, Katarzyna Brzezniakiewicz-Janus, Agnieszka Zembroń-Łacny

Publikováno v: American Journal of Men's Health, Vol 13 (2019)

Lipids play an important role in processes such as the formation of membrane cells or in steroidogenesis, where androgens which stimulate the proliferation of prostate cancer (PCa) cells are produced. Previous studies presented links between choleste

Externí odkaz: https://doaj.org/article/eb286f8f2f46413eb78c8ad01c128f15

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Novel Evidence That Alternative Pathway of Complement Cascade Activation is Required for Optimal Homing and Engraftment of Hematopoietic Stem/progenitor Cells

Autor: Mateusz Adamiak, Andrzej Ciechanowicz, Vira Chumak, Kamila Bujko, Janina Ratajczak, Katarzyna Brzezniakiewicz-Janus, Magdalena Kucia, Mariusz Z. Ratajczak

Publikováno v: Stem Cell Reviews and Reports. 18:1355-1365

We reported in the past that activation of the third (C3) and fifth element (C5) of complement cascade (ComC) is required for a proper homing and engraftment of transplanted hematopoietic stem/progenitor cells (HSPCs). Since myeloablative conditionin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997b7be6b456a48a08ce829f6d5a5799
https://doi.org/10.1007/s12015-021-10318-4

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Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts

Autor: Mateusz Adamiak, Katarzyna Brzezniakiewicz-Janus, Kamila Bujko, Arjun Thapa, Krzysztof Anusz, Mariusz Z. Ratajczak, Magda Kucia, Michał Tracz, Ahmed Abdel-Latif, Janina Ratajczak

Publikováno v: Stem Cell Reviews and Reports

Fast and efficient homing and engraftment of hematopoietic stem progenitor cells (HSPCs) is crucial for positive clinical outcomes from transplantation. We found that this process depends on activation of the Nlrp3 inflammasome, both in the HSPCs to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808e504adc50b56841c68ba0fd7e1b31
http://europepmc.org/articles/PMC7456406

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Pannexin-1 channel 'fuels' by releasing ATP from bone marrow cells a state of sterile inflammation required for optimal mobilization and homing of hematopoietic stem cells

Autor: Janina Ratajczak, Mariusz Z. Ratajczak, Agnieszka Jackowska-Tracz, Monika Cymer, Michał Tracz, Kamila Bujko, Mateusz Adamiak, Katarzyna Brzezniakiewicz-Janus, Arjun Thapa, Krzysztof Anusz

Publikováno v: Purinergic Signalling
Purinergic Signal

An efficient harvest of hematopoietic stem/progenitor cells (HSPCs) after pharmacological mobilization from the bone marrow (BM) into peripheral blood (PB) and subsequent proper homing and engraftment of these cells are crucial for clinical outcomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c930d98df74c4b1f0d910cd8faa2525b
http://europepmc.org/articles/PMC7524928

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The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine

Autor: Kamila Bujko, Katarzyna Brzezniakiewicz-Janus, Janina Ratajczak, Mateusz Adamiak, Mariusz Z. Ratajczak, Magda Kucia

Publikováno v: Stem Cell Reviews and Reports

We have recently demonstrated that purinergic signaling in bone marrow (BM) microenvironment regulates mobilization of hematopoietic stem progenitor cells (HSPCs), mesenchymal stroma cells (MSCs), endothelial progenitor cells (EPCs), and very small e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31b1d92be5620f05692ee30312cdd0f
https://doi.org/10.1007/s12015-019-09918-y

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The P2X4 purinergic receptor has emerged as a potent regulator of hematopoietic stem/progenitor cell mobilization and homing—a novel view of P2X4 and P2X7 receptor interaction in orchestrating stem cell trafficking

Autor: Daryl L. Davies, Kamila Bujko, Janina Ratajczak, Valentina Pensato, Mateusz Adamiak, Arjun Thapa, Mariusz Z. Ratajczak, Henning Ulrich, Katarzyna Brzezniakiewicz-Janus, Magda Kucia

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Recent evidence indicates that extracellular adenosine triphosphate (eATP), as a major mediator of purinergic signaling, plays an important role in regulating the mobilization and homing of hematopoietic stem progenitor cells (HSPCs). In our previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758e224fbc99df575e671e93747515b6
http://hdl.handle.net/11585/829249

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