Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Katarzyna Bober-Majnusz"'
Autor:
Zuzanna Rzepka, Katarzyna Bober-Majnusz, Justyna Magdalena Hermanowicz, Ewa Bębenek, Elwira Chrobak, Arkadiusz Surażyński, Dorota Wrześniok
Publikováno v:
Molecules, Vol 29, Iss 18, p 4408 (2024)
There are scientific studies indicating that the attachment of an indole moiety to the triterpene scaffold can lead to increased anticancer potential. Lipophilicity is one of the factors that may influence biological properties and is therefore an im
Externí odkaz:
https://doaj.org/article/64e0f48da4c4401e91b60c5b86c70202
Publikováno v:
Farmacja Polska, Vol 78, Iss 10, Pp 571-579 (2022)
The aim of this study was the chromatographic analysis of two steroid compounds; drospirenone and lynestrenol, representing the group of pro- and gestagens, respectively, and its application to determine the lipophilicity parameters of both these com
Externí odkaz:
https://doaj.org/article/e5cf5906a2694676b5bacb20cb5a04ea
Publikováno v:
Molecules, Vol 28, Iss 15, p 5822 (2023)
Due to the observed increase in the importance of computational methods in determining selected physicochemical parameters of biologically active compounds that are key to understanding their ADME/T profile, such as lipophilicity, there is a great ne
Externí odkaz:
https://doaj.org/article/d8341aaf6edd4a608a65372db2e914d1
Publikováno v:
Molecules, Vol 28, Iss 6, p 2820 (2023)
Lipophilicity in addition to the solubility, acid-base character and stability is one of the most important physicochemical parameters of a compound required to assess the ADMET properties (absorption, distribution, metabolism, excretion and toxicity
Externí odkaz:
https://doaj.org/article/8efbe2421dde4fcda185136735c0715f
Publikováno v:
Molecules, Vol 28, Iss 1, p 166 (2022)
This study aimed to evaluate the lipophilicity of a series substances lowering the concentration of uric acid in blood and anti-androgen drugs by thin-layer chromatography in reversed-phase systems (RP-TLC, RP-HPTLC) and computational methods. The ch
Externí odkaz:
https://doaj.org/article/af1176be71214d0191ad58999d519f19
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 18 (2022)
The aim of this work was the use of both cluster analysis (CA) and Principal Component Analysis (PCA) for the evaluation of the lipophilicity of selected antiandrogen drugs such as abiraterone, bicalutamide, flutamide, nilutamide, leflunomide, terifl
Externí odkaz:
https://doaj.org/article/7ea934bfc21948e1acc8153640c788bf
Publikováno v:
Molecules, Vol 26, Iss 21, p 6613 (2021)
The results presented in this paper confirm the beneficial role of an easy-to-use and low-cost thin-layer chromatography (TLC) technique for describing the retention behavior and the experimental lipophilicity parameter of two biguanide derivatives,
Externí odkaz:
https://doaj.org/article/e580766168184b329f3c02582ddd49e3
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:615-624
Chemometric analysis is often used in many fields of science. One of the most popular are cluster analysis and principal component analysis. The presented work considers those methods to evaluate the lipophilicity of groups of pentacyclic triterpene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3efd1291e1aed7908b14ee8627840c05
https://doi.org/10.32383/appdr/156084
https://doi.org/10.32383/appdr/156084
Publikováno v:
Molecules; Volume 28; Issue 1; Pages: 166
This study aimed to evaluate the lipophilicity of a series substances lowering the concentration of uric acid in blood and anti-androgen drugs by thin-layer chromatography in reversed-phase systems (RP-TLC, RP-HPTLC) and computational methods. The ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0f2777e76d3d6ff2043feed198b6e4
https://pubmed.ncbi.nlm.nih.gov/36615359
https://pubmed.ncbi.nlm.nih.gov/36615359
Publikováno v:
ECMC 2022.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4deede53131afd0b793189e03857787
https://doi.org/10.3390/ecmc2022-13262
https://doi.org/10.3390/ecmc2022-13262