Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katarzyna A. Anton"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Potentially cancerous cells undergo live apical extrusion from normal monolayers and vSrc expression induces this in zebrafish epithelia. Here, the authors show that vSrc coordinates cytokinetic ring formation, cell cycle progression, junctional inte
Externí odkaz:
https://doaj.org/article/8ff80693d50442bea784cc1754aca29d
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells undergo live apical extrusion from normal monolayers. However, the mechanism underlying this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca272e7cf0a3872f95a0343ffa294ea
https://doi.org/10.1101/246199
https://doi.org/10.1101/246199
Autor:
John Sinclair, Thomas Renné, Maria S. Balda, Mihoko Kajita, Karl Matter, Susumu Ishikawa, Atsuko Ohoka, Peter M. Benz, Yasuyuki Fujita, Claus Jørgensen, Katarzyna A. Anton
Publikováno v:
Journal of Cell Science.
At the early stages of carcinogenesis, transformation occurs in single cells within tissues. In an epithelial monolayer, such mutated cells are recognized by their normal neighbors and are often apically extruded. The apical extrusion requires cytosk