Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Katarzyna A Rejniak"'
Autor:
Amy Hall, Shari Pilon-Thomas, Matthew Beatty, Michael Poch, Jamie Blauvelt, Sarah Bazargan, Katarzyna A Rejniak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a0e68f5ec0694c36833e63f2ddda6eb1
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009206 (2021)
Radiologic images provide a way to monitor tumor development and its response to therapies in a longitudinal and minimally invasive fashion. However, they operate on a macroscopic scale (average value per voxel) and are not able to capture microscopi
Externí odkaz:
https://doaj.org/article/9d01d26f380147d1b97a378225982f6d
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 7, p e1007214 (2019)
The dynamics of tumor progression is driven by multiple factors, which can be exogenous to the tumor (microenvironment) or intrinsic (genetic, epigenetic or due to intercellular interactions). While tumor heterogeneity has been extensively studied on
Externí odkaz:
https://doaj.org/article/bec47c835d2e4cf7b18c6f703f87eac5
Autor:
Katarzyna A Rejniak, Shizhen E Wang, Nicole S Bryce, Hang Chang, Bahram Parvin, Jerome Jourquin, Lourdes Estrada, Joe W Gray, Carlos L Arteaga, Alissa M Weaver, Vito Quaranta, Alexander R A Anderson
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 8 (2010)
Most tumors arise from epithelial tissues, such as mammary glands and lobules, and their initiation is associated with the disruption of a finely defined epithelial architecture. Progression from intraductal to invasive tumors is related to genetic m
Externí odkaz:
https://doaj.org/article/4f7b0c0672d246259974bc3a9df85c58
Autor:
Alycia, Gardner, Álvaro, de Mingo Pulido, Kay, Hänggi, Sarah, Bazargan, Alexis, Onimus, Agnieszka, Kasprzak, Jose R, Conejo-Garcia, Katarzyna A, Rejniak, Brian, Ruffell
Publikováno v:
Journal for Immunotherapy of Cancer
Background T cell immunoglobulin and mucin domain containing−3 (TIM-3) blocking antibodies are currently being evaluated in clinical trials for solid and hematological malignancies. Despite its identification on T cells, TIM-3 is predominantly expr
Publikováno v:
Cancer Prevention Research. 15:B010-B010
Progression from a ductal carcinoma in situ (DCIS) to an invasive ductal carcinoma (IDC) involves changes in the surrounding extracellular matrix (ECM) fibril patterns before and during the development of ductal microinvasions, i.e., small cohorts of
Many solid tumors are characterized by dense extracellular matrix (ECM) composed of various ECM fibril proteins that provide structural support and biological context for the residing cells. The growing tumor cell colonies are capable of remodeling t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b4659d5cb89bdae4f01dfc104080d6f
https://doi.org/10.1101/2021.09.21.461296
https://doi.org/10.1101/2021.09.21.461296
Publikováno v:
Front Appl Math Stat
Frontiers in Applied Mathematics and Statistics
Frontiers in Applied Mathematics and Statistics, Frontiers Media S.A, 2021, 7, pp.680029. ⟨10.3389/fams.2021.680029⟩
Frontiers in Applied Mathematics and Statistics, Vol 7 (2021)
Frontiers in Applied Mathematics and Statistics
Frontiers in Applied Mathematics and Statistics, Frontiers Media S.A, 2021, 7, pp.680029. ⟨10.3389/fams.2021.680029⟩
Frontiers in Applied Mathematics and Statistics, Vol 7 (2021)
International audience; The specific structure of the extracellular matrix (ECM), and in particular the density and orientation of collagen fibres, plays an important role in the evolution of solid cancers. While many experimental studies discussed t
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009206 (2021)
PLoS Computational Biology
PLoS Computational Biology
Radiologic images provide a way to monitor tumor development and its response to therapies in a longitudinal and minimally invasive fashion. However, they operate on a macroscopic scale (average value per voxel) and are not able to capture microscopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce9a61d25d79ec233e00a7c6d0f4923
https://doi.org/10.1101/2021.03.18.435990
https://doi.org/10.1101/2021.03.18.435990
Publikováno v:
Bulletin of Mathematical Biology. 82
Traditionally, the monolayer (two-dimensional) cell cultures are used for initial evaluation of the effectiveness of anticancer drugs. In particular, these experiments provide the [Formula: see text] curves that determine drug concentration that can