Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Katarzyna A, Nałęcz"'
Autor:
Katarzyna A. Nałęcz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cancer cells are characterized by quick growth and proliferation, demanding constant supply of various nutrients. Several plasma membrane transporters delivering such compounds are upregulated in cancer. Solute carrier family 6 member 14 (SLC6A14), k
Externí odkaz:
https://doaj.org/article/a15652c259ff4daaae20e60692938da8
Publikováno v:
Cells, Vol 10, Iss 7, p 1800 (2021)
Cancer cells need a constant supply of nutrients. SLC6A14, an amino acid transporter B0,+ (ATB0,+) that is upregulated in many cancers, transports all but acidic amino acids. In its exit from the endoplasmic reticulum (ER), it is recognized by the SE
Externí odkaz:
https://doaj.org/article/462da529a0de45aea3a80f6e961909ff
Publikováno v:
Archives of Biochemistry and Biophysics. 742:109616
Publikováno v:
Biochemical and biophysical research communications. 614
SLC6A14 is a plasma membrane transporter specific for neutral and basic amino acids, upregulated in many tumors. This study focused on breast cancer cell lines, showing the fully glycosylated band, known to be at the cell surface, in estrogen recepto
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:1544-1555
Plasma membrane transporter SLC6A14 transports all neutral and basic amino acids in a Na/Cl - dependent way and it is up-regulated in many types of cancer. Mass spectrometry analysis of overexpressed SLC6A14-associated proteins identified, among othe
Autor:
Magdalena Czeredys, Łukasz Samluk, Katarzyna Michalec, Karolina Tułodziecka, Krzysztof Skowronek, Katarzyna A Nałęcz
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82105 (2013)
OCTN2--the Organic Cation Transporter Novel family member 2 (SLC22A5) is known to be a xenobiotic/drug transporter. It transports as well carnitine--a compound necessary for oxidation of fatty acids and mutations of its gene cause primary carnitine d
Externí odkaz:
https://doaj.org/article/841d30afd8e34c64943214032f99c299
Publikováno v:
Journal of neurochemistryREFERENCES. 156(5)
Gliomas are the most common primary malignant brain tumor in adults, but current treatment for glioblastoma multiforme (GBM) is insufficient. Even though glucose is the primary energetic substrate of glioma cells, they are capable of using fatty acid
Autor:
Katarzyna Pełczyńska-Nałęcz
Publikováno v:
Sprawy Międzynarodowe. 71:31-41
Autor:
Barbara Juraszek, Katarzyna A. Nałęcz
Publikováno v:
Molecules
Oxidation of fatty acids uses l-carnitine to transport acyl moieties to mitochondria in a so-called carnitine shuttle. The process of β-oxidation also takes place in cancer cells. The majority of carnitine comes from the diet and is transported to t
Autor:
Łukasz Samluk, Michael Freissmuth, Dominika Jurkiewicz-Trząska, Sonja Sucic, Vasylyna Kovalchuk, Barbara Juraszek, Katarzyna A. Nałęcz
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
A plasma membrane amino acid transporter B0,+ (ATB0,+), encoded by the SLC6A14 gene, is specific for neutral and basic amino acids. It is up-regulated in several types of malignant cancers. Neurotransmitter transporters of the SLC6 family interact wi