GABAergic synapses onto SST and PV interneurons in the CA1 hippocampal region show cell-specific and integrin-dependent plasticity

Autor: Patrycja Brzdąk, Katarzyna Lebida, Marcin Wyroślak, Jerzy W. Mozrzymas

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract It is known that GABAergic transmission onto pyramidal neurons shows different forms of plasticity. However, GABAergic cells innervate also other inhibitory interneurons and plasticity phenomena at these projections remain largely unknown. S

Externí odkaz: https://doaj.org/article/5df6e28c9d2c46c3a8e9f6e67e9231e7

Induction of Inhibitory Synaptic Plasticity Enhances Tonic Current by Increasing the Content of α5-Subunit Containing GABAA Receptors in Hippocampal Pyramidal Neurons

Autor: Marcin Wyroślak, Katarzyna Lebida, Jerzy W. Mozrzymas

Publikováno v: Neuroscience. 467:39-46

It is known that besides synaptic inhibition, there is a persistent component of inhibitory drive mediated by tonic currents which is believed to mediate majority of the total inhibitory charge in hippocampal neurons. Tonic currents, depending on cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fa13a7e6c56c75ecc73a09fa84eb948
https://doi.org/10.1016/j.neuroscience.2021.05.020

17β-estradiol affects GABAergic transmission in developing hippocampus

Autor: Jerzy W. Mozrzymas, Katarzyna Lebida, Tomasz Wójtowicz

Publikováno v: Brain Research. 1241:7-17

Estrogens are potent modulators of the nervous system. In particular, 17beta-estradiol was shown to affect GABAergic synaptic transmission in hippocampus of adult animals in vivo but much less is known on the impact of this hormone on the GABAergic s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4538f86a7a9a915d3262f124583f526b
https://doi.org/10.1016/j.brainres.2008.09.005

GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons

Autor: Paulina Wyrembek, Katarzyna Lebida, Katarzyna Mercik, Tomasz Wójtowicz, Michał Piast, Jerzy W. Mozrzymas

Publikováno v: The Journal of Physiology. 585:29-46

Benzodiazepines (BDZs) are known to increase the amplitude and duration of IPSCs. Moreover, at low [GABA], BDZs strongly enhance GABAergic currents suggesting the up-regulation of agonist binding while their action on gating remains a matter of debat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::460198bdfb4869ff105289c9bb788bdb
https://doi.org/10.1113/jphysiol.2007.143602

Long term potentiation affects intracellular metalloproteinases activity in the mossy fiber-CA3 pathway

Autor: D Gendosz, Leszek Kaczmarek, D. Drulis-Fajdasz, Agnieszka Gomulkiewicz, Jerzy W. Mozrzymas, Katarzyna Lebida, Marco Capogna, Piotr Dziegiel, Grzegorz M. Wilczynski, Tomasz Wójtowicz, Marzena Podhorska-Okolow, Grzegorz Wiera, Aleksandra Piotrowska

Publikováno v: Wiera, G, Wójtowicz, T, Lebida, K, Piotrowska, A, Drulis-Fajdasz, D, Gomułkiewicz, A, Gendosz, D, Podhorska-Okołów, M, Capogna, M, Wilczyński, G, Dzięgiel, P, Kaczmarek, L & Mozrzymas, J W 2012, ' Long term potentiation affects intracellular metalloproteinases activity in the mossy fiber-CA3 pathway ', Molecular and Cellular Neuroscience, vol. 50, no. 2, pp. 147-59 . https://doi.org/10.1016/j.mcn.2012.04.005

Matrix Metalloproteinases (MMPs) are a family of endopeptidases known to process extracellular proteins. In the last decade, studies carried out mainly on the Schaffer collateral — CA1 hippocampal projection have provided solid evidence that MMPs r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f859c76952cbc4f92beff531fff6f22
https://pure.au.dk/portal/da/publications/long-term-potentiation-affects-intracellular-metalloproteinases-activity-in-the-mossy-fiberca3-pathway(d387ef74-680d-4f86-acac-094dd56f74fa).html