Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Katarzyna, Dzitko"'
Autor:
Maciej Chyb, Bożena Dziadek, Katarzyna Dzitko, Bartłomiej Tomasz Ferra, Malwina Kawka, Lucyna Holec-Gąsior, Justyna Gatkowska
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Toxoplasmosis caused by the opportunistic, cosmopolitan protozoan Toxoplasma gondii is one of the most common parasitoses in the world. Although it may prove dangerous or even fatal for immunocompromised individuals, immunoprophylaxis for hu
Externí odkaz:
https://doaj.org/article/4b41022f7fbd49bcb1fba7a700d1c3ff
Autor:
Joanna Wasiak, Pola Głowacka, Agnieszka Pudlarz, Adam M. Pieczonka, Katarzyna Dzitko, Janusz Szemraj, Monika Witusik-Perkowska
Publikováno v:
Molecules, Vol 29, Iss 10, p 2292 (2024)
Breast cancer is associated with high mortality and morbidity rates. As about 20–30% of patients exhibiting ER-positive phenotype are resistant to hormonal treatment with the standard drug tamoxifen, finding new therapies is a necessity. Postbiotic
Externí odkaz:
https://doaj.org/article/80dda73140e74232bd67a2b8ac46343b
Autor:
Malwina Kawka, Renata Płocińska, Przemysław Płociński, Jakub Pawełczyk, Marcin Słomka, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek, Jarosław Dziadek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn the course of tuberculosis (TB), the level of major acute phase protein, namely serum amyloid A (hSAA-1), increases up to a hundredfold in the pleural fluids of infected individuals. Tubercle bacilli infecting the human host can be ops
Externí odkaz:
https://doaj.org/article/1bf4057249fa42e996f9c1b0a87d14a9
Autor:
Lidia Węglińska, Adrian Bekier, Nazar Trotsko, Barbara Kaproń, Tomasz Plech, Katarzyna Dzitko, Agata Paneth
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2621-2634 (2022)
A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the com
Externí odkaz:
https://doaj.org/article/79d58e45c8734949b193085685825372
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1145-1164 (2021)
We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain of Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found with the
Externí odkaz:
https://doaj.org/article/c469cec21766439e99c28e34fbdb3bfc
Autor:
Katarzyna Dzitko, Barbara Kaproń, Agata Paneth, Adrian Bekier, Tomasz Plech, Piotr Paneth, Nazar Trotsko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2069 (2023)
Two distinct intracellular pathogens, namely Mycobacterium tuberculosis (Mtb) and Toxoplasma gondii (Tg), cause major public health problems worldwide. In addition, serious and challenging health problems of co-infections of Tg with Mtb have been rec
Externí odkaz:
https://doaj.org/article/0e7149ec297147a2ba204552ac8e7e75
Autor:
Adrian Bekier, Anna Brzostek, Agata Paneth, Bożena Dziadek, Jarosław Dziadek, Justyna Gatkowska, Katarzyna Dzitko
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3213 (2022)
Approximately one-third of the human population is infected with the intracellular cosmopolitan protozoan Toxoplasma gondii (Tg), and a specific treatment for this parasite is still needed. Additionally, the increasing resistance of Tg to drugs has b
Externí odkaz:
https://doaj.org/article/73d23cfc393c417d9500ff5bd4764693
Autor:
Adrian Bekier, Malwina Kawka, Jakub Lach, Jarosław Dziadek, Agata Paneth, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek
Publikováno v:
Cells, Vol 10, Iss 12, p 3476 (2021)
Mycobacterium tuberculosis (Mtb) is an intracellular pathogenic bacterium and the causative agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial infections, as it poses major health, social and economic challenges at
Externí odkaz:
https://doaj.org/article/80154c38a6024a128e49dc4d9b962750
Autor:
Bartłomiej Tomasz Ferra, Lucyna Holec-Gąsior, Justyna Gatkowska, Bożena Dziadek, Katarzyna Dzitko, Weronika Grąźlewska, Dariusz Lautenbach
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217866 (2019)
This study presents an evaluation of four tetravalent recombinant chimeric proteins containing fragments of the Toxoplasma gondii antigens, SAG2, GRA1, ROP1 and AMA1, as potential replacements of a the soluble, whole-cell tachyzoite lysate (TLA) used
Externí odkaz:
https://doaj.org/article/efae67d464814d189ef00f4f0c91565b
Autor:
Malwina Kawka, Anna Brzostek, Katarzyna Dzitko, Jakub Kryczka, Radosław Bednarek, Renata Płocińska, Przemysław Płociński, Dominik Strapagiel, Justyna Gatkowska, Jarosław Dziadek, Bożena Dziadek
Publikováno v:
Cells, Vol 10, Iss 5, p 1264 (2021)
As a very successful pathogen with outstanding adaptive properties, Mycobacterium tuberculosis (Mtb) has developed a plethora of sophisticated mechanisms to subvert host defenses and effectively enter and replicate in the harmful environment inside p
Externí odkaz:
https://doaj.org/article/1f237876c40d41898c7536db5b13ffae