Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Katarzyna, Borg"'
Autor:
Kavita Ramji, Tomasz M. Grzywa, Anna Sosnowska, Aleksandra Paterek, Marta Okninska, Zofia Pilch, Joanna Barankiewicz, Filip Garbicz, Katarzyna Borg, Urszula Bany-Laszewicz, Abdesamad Zerrouqi, Beata Pyrzynska, Anna Rodziewicz-Lurzynska, Diana Papiernik, Piotr Sklepkiewicz, Hanna Kedzierska, Adam Staruch, Radoslaw Sadowski, Olga Ciepiela, Ewa Lech-Maranda, Przemyslaw Juszczynski, Urszula Mackiewicz, Michal Maczewski, Dominika Nowis, Jakub Golab
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite constantly evolving therapeutic approaches including various types of immunotherapy. Increased arginase activity has been associated with potent suppression of T-c
Externí odkaz:
https://doaj.org/article/c1756db456d04ea59f57f4c24f50c6c9
Autor:
Marta Libura, Emilia Bialopiotrowicz, Sebastian Giebel, Agnieszka Wierzbowska, Gail J. Roboz, Beata Piatkowska-Jakubas, Marta Pawelczyk, Patryk Gorniak, Katarzyna Borg, Magdalena Wojtas, Izabella Florek, Karolina Matiakowska, Bozena Jazwiec, Iwona Solarska, Monika Noyszewska-Kania, Karolina Piechna, Magdalena Zawada, Sylwia Czekalska, Zoriana Salamanczuk, Karolina Karabin, Katarzyna Wasilewska, Monika Paluszewska, Elzbieta Urbanowska, Justyna Gajkowska-Kulik, Grazyna Semenczuk, Justyna Rybka, Tomasz Wrobel, Anna Ejduk, Dariusz Kata, Sebastian Grosicki, Tadeusz Robak, Agnieszka Pluta, Agata Kominek, Katarzyna Piwocka, Karolina Pyziak, Agnieszka Sroka-Porada, Anna Wrobel, Agnieszka Przybylowicz, Marzena Wojtaszewska, Krzysztof Lewandowski, Lidia Gil, Agnieszka Piekarska, Wanda Knopinska, Lukasz Bolkun, Krzysztof Warzocha, Kazimierz Kuliczkowski, Tomasz Sacha, Grzegorz Basak, Wieslaw Wiktor Jedrzejczak, Jerzy Holowiecki, Przemysław Juszczynski, Olga Haus
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) genes occur in about 20% patients with acute myeloid leukemia (AML), leading to DNA hypermethylation and epigenetic deregulation. We assessed the prognostic significance of IDH1/2 mutati
Externí odkaz:
https://doaj.org/article/4d3149eacd9c4e0bbd45e7fcb3834c44
Autor:
Aleksander Salomon-Perzyński, Joanna Barankiewicz, Marcin Machnicki, Irena Misiewicz-Krzemińska, Michał Pawlak, Sylwia Radomska, Agnieszka Krzywdzińska, Aleksandra Bluszcz, Piotr Stawiński, Małgorzata Rydzanicz, Natalia Jakacka, Iwona Solarska, Katarzyna Borg, Zofia Spyra-Górny, Tomasz Szpila, Bartosz Puła, Sebastian Grosicki, Tomasz Stokłosa, Rafał Płoski, Ewa Lech-Marańda, Jana Jakubikova, Krzysztof Jamroziak
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1674 (2022)
Clonal evolution drives treatment failure in multiple myeloma (MM). Here, we used a custom 372-gene panel to track genetic changes occurring during MM progression at different stages of the disease. A tumor-only targeted next-generation DNA sequencin
Externí odkaz:
https://doaj.org/article/157b567d61334d2ca4fc78ec78d72b72
Publikováno v:
Hematologia. 11:253-258
The development of targeted therapies in AML patients enabling treatment individualization, such as new FLT3 tyrosine kinase inhibitors, is a promising option for improving treatment outcomes and prolonging patient survival. However, the treatment of
Autor:
Magdalena Zawada, Jerzy Holowiecki, Magdalena Wojtas, Sebastian Giebel, Agnieszka Przybylowicz, Anna Ejduk, I. Florek, Agnieszka Wierzbowska, Dariusz Kata, Kazimierz Kuliczkowski, Tomasz Wróbel, Beata Piatkowska-Jakubas, Przemysław Juszczynski, Marta Libura, Katarzyna Piwocka, Sylwia Czekalska, Marzena Wojtaszewska, Emilia Bialopiotrowicz, Karolina Matiakowska, Iwona Solarska, Tomasz Sacha, Patryk Gorniak, Tadeusz Robak, Elżbieta Urbanowska, Gail J. Roboz, Wiesław Wiktor Jędrzejczak, Agnieszka Sroka-Porada, Agnieszka Pluta, Wanda Knopinska, Justyna Gajkowska-Kulik, Krzysztof Warzocha, Anna Wróbel, Monika Paluszewska, Sebastian Grosicki, Karolina Karabin, Marta Pawelczyk, Bozena Jazwiec, Katarzyna Borg, Justyna Rybka, Grzegorz W. Basak, Olga Haus, Lidia Gil, Lukasz Bolkun, Agata Kominek, Grazyna Semenczuk, Agnieszka Piekarska, Krzysztof Lewandowski, Zoriana Salamanczuk, Karolina Pyziak, Katarzyna Wasilewska, Karolina Piechna, Monika Noyszewska-Kania
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) genes occur in about 20% patients with acute myeloid leukemia (AML), leading to DNA hypermethylation and epigenetic deregulation. We assessed the prognostic significance of IDH1/2 mutations (IDH1
Autor:
Aleksander, Salomon-Perzyński, Aleksandra, Bluszcz, Agnieszka, Krzywdzińska, Zofia, Spyra-Górny, Natalia, Jakacka, Joanna, Barankiewicz, Katarzyna, Borg, Iwona, Solarska, Tomasz, Szpila, Bartosz, Puła, Sebastian, Grosicki, Krzysztof, Jamroziak
Publikováno v:
Polish archives of internal medicine. 130(6)
Prognosis of patients with newly diagnosed multiple myeloma (MM), a third most common hematological cancer, is dependent on baseline cytogenetics. However, little is known about the prognostic significance of cytogenetic evolution (CE) at the time be
Autor:
Iwona Solarska, Aleksandra Bluszcz, Katarzyna Borg, Sebastian Grosicki, Zofia Spyra-Gorny, Krzysztof Jamroziak, Bartosz Pula, Natalia Jakacka, Tomasz Szpila, Joanna Barankiewicz, Aleksander Salomon-Perzyński, Agnieszka Krzywdzińska
Publikováno v:
Polish Archives of Internal Medicine.
Introduction Prognosis of patients with newly diagnosed multiple myeloma (MM), a third most common hematological cancer, is dependent on baseline cytogenetics. However, little is known about the prognostic significance of cytogenetic evolution (CE) a
Autor:
Michal Galezowski, Karolina Piechna, Ewa Lech-Marańda, Ewa Jabłońska, Maja Wasylecka-Juszczyńska, Monika Noyszewska-Kania, Tomasz Sewastianik, Patryk Górniak, Przemyslaw Juszczynski, Anna Polak, Maciej Szydlowski, Emilia Bialopiotrowicz, Renata Windak, Bożena Katarzyna Budziszewska, Wojciech Czardybon, Bartosz Pula, Grazyna Nowak, Hanna Makuch-Łasica, Krzysztof Brzózka, Aleksandra Bluszcz, Krzysztof Warzocha, Katarzyna Borg
Publikováno v:
Journal of Cellular and Molecular Medicine
Lymph node microenvironment provides chronic lymphocytic leukaemia (CLL) cells with signals promoting their survival and granting resistance to chemotherapeutics. CLL cells overexpress PIM kinases, which regulate apoptosis, cell cycle and migration.
Autor:
Piotr Stawiński, Iwona Solarska, Marcin M Machnicki, Malgorzata Kurkowiak, Tomasz Stoklosa, Małgorzata Rydzanicz, Monika Pepek, Katarzyna Borg, Rafał Płoski
Publikováno v:
Acta Haematologica Polonica. 48:343-349
We have performed detailed analysis of the genomic landscape of commercially available K562 cells, employing targeted enrichment of nearly 1300 cancer-related genes followed by next-generation sequencing (NGS) and also classical cytogenetics. Deep se
Autor:
Barbara Pienkowska-Grela, Anna Czyż, Barbara Nasiłowska-Adamska, Katarzyna Borg, Krzysztof Warzocha, Iwona Solarska
Publikováno v:
European Journal of Haematology. 99:255-261
Purpose FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) is aberration associated with poor prognosis in AML. We have analyzed the expression of MDR-1, MRP-1, and BCRP mRNA in relation to FLT3-ITD in 100 AML adult patients with norma