Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katarina Reis"'
Publikováno v:
Oncotarget
Malignant mesotheliomas (MMs) are highly aggressive mesenchymal tumors that originate from mesothelial cells lining serosal cavities; i.e., the pleura, peritoneum, and pericardium. Classically, there is a well-established link between asbestos exposu
Publikováno v:
European Journal of Cell Biology. 97:393-401
The atypical Rho GTPase RhoD has previously been shown to have a major impact on the organization and function of the actin filament system. However, when first discovered, RhoD was found to regulate endosome trafficking and dynamics and we therefore
Publikováno v:
Experimental Cell Research. 352:255-264
RhoD belongs to the Rho GTPases, a protein family responsible for the regulation and organization of the actin cytoskeleton, and, consequently, many cellular processes like cell migration, cell division and vesicle trafficking. Here, we demonstrate t
Autor:
Katja T. Koessmeier, Radovan Dvorsky, Mamta Jaiswal, Pontus Aspenström, Urszula Derewenda, Kazem Nouri, Ehsan Amin, Katarina Reis, Mohammad Reza Ahmadian, Avril V. Somlyo
Publikováno v:
Journal of Biological Chemistry. 291:20353-20371
RHO GTPase-activating proteins (RHOGAPs) are one of the major classes of regulators of the RHO-related protein family that are crucial in many cellular processes, motility, contractility, growth, differentiation, and development. Using database searc
Publikováno v:
Brain Research. 1322:1-7
Activated microglia cells, observed during chronic inflammation, produce and secrete compounds that at high concentrations or during sustained production might cause neuronal cell death. Inducible nitric oxide synthase (iNOS) is expressed in response
Publikováno v:
Neuroscience Letters. 389:133-136
The molecular mechanism of neurodegeneration in prion diseases remains largely uncertain, but one of the features of infected cells is higher sensitivity to induced oxidative stress. In this study, we have investigated the role of iron in hydrogen pe
Publikováno v:
Journal of Neuroscience Research. 79:368-374
We report the effects of amyloid precursor protein (APP) fragment 714-723 (APP(714-723); peptide P1) and its V717F and V717G mutants (peptides P2 and P3, respectively) on G-protein activity ([35S]GTPgammaS binding) in membranes from postmortem human
Publikováno v:
Experimental cell research. 333(2)
RhoD is a member of the Rho GTPase family and it coordinates actin dynamics and membrane trafficking. Activation of RhoD results in formation of filopodia, dissolution of stress fibers, and the subsequent formation of short actin bundles. In addition
Publikováno v:
FEBS letters. 583(9)
Mitochondria are organelles of elaborate structure that in addition to supplying cellular energy, have significant roles in calcium homeostasis and apoptosis. Failure to maintain mitochondrial dynamics results in neurodegenerative diseases and neurom
Autor:
Martin Peterka, Pontus Aspenström, Benoît Kornmann, Katarina Reis, Andre Melnik, Gil Kanfer, Thibault Courtheoux, Martin Soste, Matthias Peter, Paola Picotti, Sonja Meier
Publikováno v:
Nature Communications
Europe PubMed Central
Nature Communications, 6
NATURE COMMUNICATIONS
Europe PubMed Central
Nature Communications, 6
NATURE COMMUNICATIONS
Although chromosome partitioning during mitosis is well studied, the molecular mechanisms that allow proper segregation of cytoplasmic organelles in human cells are poorly understood. Here we show that mitochondria interact with growing microtubule t