Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Katarina Kluckova"'
Autor:
Katarina Kluckova, Andrew J. Clear, Annalisa D’Avola, Laura Z. Rassenti, Thomas J. Kipps, John G. Gribben, John C. Riches
Publikováno v:
HemaSphere, Vol 6, Iss 6, p e722 (2022)
It has been unclear what role metabolism is playing in the pathophysiology of chronic lymphocytic leukemia (CLL). One reason is that the study of CLL metabolism is challenging due to the resting nature of circulating CLL cells. Also, it is not clear
Externí odkaz:
https://doaj.org/article/f8ebec7a7ae54bc1a1256e29c145678a
Autor:
Annalisa D’Avola, Nathalie Legrave, Mylène Tajan, Probir Chakravarty, Ryan L. Shearer, Hamish W. King, Katarina Kluckova, Eric C. Cheung, Andrew J. Clear, Arief S. Gunawan, Lingling Zhang, Louisa K. James, James I. MacRae, John G. Gribben, Dinis P. Calado, Karen H. Vousden, John C. Riches
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
The synthesis of serine from glucose is a key metabolic pathway supporting cellular proliferation in healthy and malignant cells. Despite this, the role that this aspect of metabolism plays in germinal center biology and pathology is not known. Here,
Externí odkaz:
https://doaj.org/article/f77224ae7f904f2ab572db0a1463b41e
Autor:
Kate E.R. Hollinshead, Haydn Munford, Katherine L. Eales, Chiara Bardella, Chunjie Li, Cristina Escribano-Gonzalez, Alpesh Thakker, Yannic Nonnenmacher, Katarina Kluckova, Mark Jeeves, Robert Murren, Federica Cuozzo, Dan Ye, Giulio Laurenti, Wei Zhu, Karsten Hiller, David J. Hodson, Wei Hua, Ian P. Tomlinson, Christian Ludwig, Ying Mao, Daniel A. Tennant
Publikováno v:
Cell Reports, Vol 22, Iss 12, Pp 3107-3114 (2018)
Summary: Since the discovery of mutations in isocitrate dehydrogenase 1 (IDH1) in gliomas and other tumors, significant efforts have been made to gain a deeper understanding of the consequences of this oncogenic mutation. One aspect of the neomorphic
Externí odkaz:
https://doaj.org/article/26706adfa2534c22a56f1079550fabca
Autor:
Yasir S. Elhassan, Katarina Kluckova, Rachel S. Fletcher, Mark S. Schmidt, Antje Garten, Craig L. Doig, David M. Cartwright, Lucy Oakey, Claire V. Burley, Ned Jenkinson, Martin Wilson, Samuel J.E. Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A. Tennant, Peter Nightingale, Gareth A. Wallis, Konstantinos N. Manolopoulos, Charles Brenner, Andrew Philp, Gareth G. Lavery
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1717-1728.e6 (2019)
Summary: Nicotinamide adenine dinucleotide (NAD+) is modulated by conditions of metabolic stress and has been reported to decline with aging in preclinical models, but human data are sparse. Nicotinamide riboside (NR) supplementation ameliorates meta
Externí odkaz:
https://doaj.org/article/79c9efd10ba94a93a3a872aaaf64b487
Autor:
Lan-Feng Dong, Jaromira Kovarova, Martina Bajzikova, Ayenachew Bezawork-Geleta, David Svec, Berwini Endaya, Karishma Sachaphibulkij, Ana R Coelho, Natasa Sebkova, Anna Ruzickova, An S Tan, Katarina Kluckova, Kristyna Judasova, Katerina Zamecnikova, Zuzana Rychtarcikova, Vinod Gopalan, Ladislav Andera, Margarita Sobol, Bing Yan, Bijay Pattnaik, Naveen Bhatraju, Jaroslav Truksa, Pavel Stopka, Pavel Hozak, Alfred K Lam, Radislav Sedlacek, Paulo J Oliveira, Mikael Kubista, Anurag Agrawal, Katerina Dvorakova-Hortova, Jakub Rohlena, Michael V Berridge, Jiri Neuzil
Publikováno v:
eLife, Vol 6 (2017)
Recently, we showed that generation of tumours in syngeneic mice by cells devoid of mitochondrial (mt) DNA (ρ0 cells) is linked to the acquisition of the host mtDNA. However, the mechanism of mtDNA movement between cells remains unresolved. To deter
Externí odkaz:
https://doaj.org/article/4285105d6a3d4ae5a57e35604fc4c03d
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Succinate dehydrogenase is a key enzyme in the tricarboxylic acid cycle and the electron transport chain. All four subunits of succinate dehydrogenase are tumor suppressor genes predisposing to paraganglioma, but only mutations in the SDHB subunit ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8344fed531abd70c4e2067dd3f8dac8
https://doi.org/10.1158/0008-5472.c.6513153.v1
https://doi.org/10.1158/0008-5472.c.6513153.v1
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Figure 1 - Supplementary Figure 2 - Supplementary Figure 3 - Supplementary Figure 4 - Supplementary Figure 5 - Supplementary Figure 6 - Supplementary Table 1 - Supplementary Table 2 - Supplementary Table 3 - Supplementary Table 4 - Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa5c66a17bcd42509bb7c99b59f814
https://doi.org/10.1158/0008-5472.22428819
https://doi.org/10.1158/0008-5472.22428819
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Table 2 Related to Figure 2. Differentially methylated gene-based features in Sdhb-/- versus Sdhd-/- imCCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b04c08f42c8e0660b2c6f91c099c84
https://doi.org/10.1158/0008-5472.22428816.v1
https://doi.org/10.1158/0008-5472.22428816.v1
Publikováno v:
Cancers. 14(22)
There have been significant recent advances in the understanding of the role of metabolism in normal and malignant B-cell biology. Previous research has focused on the role of MYC and mammalian target of rapamycin (mTOR) and how these interact with B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0484b73408ce5c06ab40aaa82d0212
https://pubmed.ncbi.nlm.nih.gov/36428647
https://pubmed.ncbi.nlm.nih.gov/36428647
Autor:
Katarina, Kluckova, Andrew J, Clear, Annalisa, D'Avola, Laura Z, Rassenti, Thomas J, Kipps, John G, Gribben, John C, Riches
Publikováno v:
HemaSphere. 6(6)
It has been unclear what role metabolism is playing in the pathophysiology of chronic lymphocytic leukemia (CLL). One reason is that the study of CLL metabolism is challenging due to the resting nature of circulating CLL cells. Also, it is not clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5d40c1a741d517f15135da08577af39
https://pubmed.ncbi.nlm.nih.gov/35747847
https://pubmed.ncbi.nlm.nih.gov/35747847