Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Katarina J, Makaravage"'
Autor:
Andrew V. Mossine, Allen F. Brooks, Naoko Ichiishi, Katarina J. Makaravage, Melanie S. Sanford, Peter J. H. Scott
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access
Externí odkaz:
https://doaj.org/article/7daafde7551a4666b9c628beed7fc804
Publikováno v:
Nuclear Medicine and Biology. :56-86
Hydrogen cyanide (HCN) is a versatile synthon for generating carbon‑carbon and carbon-heteroatom bonds. Unlike other one-carbon synthons (i.e., CO, CO2), HCN can function as a nucleophile (as in potassium cyanide, KCN) and an electrophile (as in cy
Autor:
So Jeong Lee, Katarina J. Makaravage, María T Morales-Colón, Jay S. Wright, Peter J. H. Scott, Melanie S. Sanford, Allen F. Brooks
Publikováno v:
J Org Chem
This report describes a method for the nucleophilic radiofluorination of (hetero)aryl chlorides, (hetero)aryl triflates, and nitroarenes using a combination of [(18)F]KF•K(2.2.2) and Me(4)N HCO(3) for the in situ formation of a strongly nucleophili
Autor:
Sameer Tyagi, Bruce P. McKillican, Tolani K. Salvador, Moses G. Gichinga, William J. Eberle, Russell Viner, Katarina J. Makaravage, Trey S. Johnson, C. Adam Russell, Subho Roy
Publikováno v:
The Journal of organic chemistry. 87(9)
A bioinspired synthesis of Pinoxaden metabolites
Autor:
Melanie S. Sanford, Allen F. Brooks, Katarina J. Makaravage, Peter J. H. Scott, Jay S. Wright
Publikováno v:
Handbook of Radiopharmaceuticals
Autor:
Skylar Norman, Katarina J. Makaravage, Amanda C. Jones, Yuyang Zhu, Brock R. Yager, Ruichen Lan, Dwaine D. Hodges, Cynthia S. Day, Wentong Zhou, Fred L. Liu, Carolin Griebel
Publikováno v:
Organometallics. 39:2665-2671
This paper describes the synthesis and characterization of RP(o-biphenyl)2 phosphine ligands (where R = PhO, Ph, and t-Bu), corresponding gold(I) chloride precatalysts, gold(I) triflate catalysts, and gold(I) π-complexes. All ligands and gol
Autor:
Thomas Erhard, Melanie S. Sanford, Christian Bruetting, Sean S. Tanzey, Bradford D. Henderson, Andrew V. Mossine, Jason Miller, Naoko Ichiishi, Peter J. H. Scott, Allen F. Brooks, Marc B. Skaddan, Katarina J. Makaravage
Publikováno v:
Nature Protocols. 15:1742-1759
[18F]6-fluoro-L-DOPA ([18F]FDOPA) is a diagnostic radiopharmaceutical for positron emission tomography (PET) imaging that is used to image Parkinson's disease, brain tumors, and focal hyperinsulinism of infancy. Despite these important applications,
Autor:
Katarina J. Makaravage, Peter J. H. Scott, Wade Winton, Allen F. Brooks, Liam S. Sharninghausen, Melanie S. Sanford
Publikováno v:
J Am Chem Soc
[(18)F]-labeled aryl fluorides are widely used as radiotracers for positron emission tomography (PET) imaging. Aryl halides (ArX) are particularly attractive precursors to these radiotracers, as they are readily available, inexpensive, and stable. Ho
Publikováno v:
Angewandte Chemie International Edition. 58:3119-3122
A Cu-mediated ortho-C-H radiofluorination of aromatic carboxylic acids that are protected as 8-aminoquinoline benzamides is described. The method uses K18 F and is compatible with a wide range of functional groups. The reaction is showcased in the hi
Autor:
Allen F. Brooks, So Jeong Lee, Katarina J. Makaravage, Peter J. H. Scott, Melanie S. Sanford, Andrew V. Mossine, Naoko Ichiishi
Publikováno v:
Chemical Communications. 55:2976-2979
This report describes a Pd-mediated C–H radiofluorination of 8-methylquinoline derivatives with no-carrier-added Ag[18F]F. To achieve this transformation, a new method was developed for the generation of Ag[18F]F using a sep-pak cartridge. The C–