Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Katarina, Carlsson"'
Publikováno v:
American Journal of Nephrology. 31:178-188
Background: The pathogenesis of contrast-induced nephropathy (CIN) is still poorly understood and apoptosis via oxidative stress has been proposed as one possible mechanism. We therefore studied the apoptotic signaling mechanism in CIN and also teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5dc07c21f16cc4411821a03b1e5eed5
https://doi.org/10.1159/000268161
https://doi.org/10.1159/000268161
Publikováno v:
Free Radical Research. 39:595-601
The SH compound glutathione (GSH) is involved in several fundamental functions in the cell, including protection against reactive oxygen species (ROS). Here, we studied the effect on oxidative DNA damage in cultured skin fibroblasts from patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8e50e03a9adc036ab01754c90a82c7
https://doi.org/10.1080/10715760500045772
https://doi.org/10.1080/10715760500045772
Autor:
Ellinor Ristoff, Andreas Winkler, Agne Larsson, Svante Norgren, Runa Njålsson, Katarina Carlsson
Publikováno v:
Human Genetics. 116:384-389
Glutathione synthetase (GS) deficiency is a rare autosomal recessive disorder. The clinical phenotype varies widely, and nearly 30 different mutations in the GSS gene have been identified. In the present study, genotype, enzyme activity, metabolite l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b434759349b20380875df85fe2dc8a82
https://doi.org/10.1007/s00439-005-1255-6
https://doi.org/10.1007/s00439-005-1255-6
Autor:
Runa Njålsson, Mary E. Anderson, Katarina Carlsson, Vikas S. Bhansali, Agne Larsson, Jia-Li Luo, Rudolf Ladenstein, Svante Norgren, Lennart Nilsson
Publikováno v:
Biochemical Journal. 381:489-494
Patients with hereditary glutathione synthetase deficiency suffer from haemolytic anaemia, 5-oxoprolinuria, metabolic acidosis, recurrent bacterial infections and various degrees of central nervous system dysfunction. To investigate the molecular bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78358cc085f1cbc495ed76bd126019e8
https://doi.org/10.1042/bj20040114
https://doi.org/10.1042/bj20040114
Protective effects of N-acetylcysteine amide (NACA) on gentamicin-induced apoptosis in LLC-PK1 cells
Publikováno v:
Renal failure. 34(4)
Apoptosis plays a critical role in the pathogenesis of gentamicin (Gen)-induced nephrotoxicity. However, the underlying molecular mechanisms still remain unclear. In this study, we addressed the role of p38 mitogen-activated protein kinase (MAPK)/ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e39ca3f98e05461d60163e3025d941
https://pubmed.ncbi.nlm.nih.gov/22486232
https://pubmed.ncbi.nlm.nih.gov/22486232
Autor:
Linu S. Abraham, Michael W. Lieberman, Björn Rozell, Abdelaziz Elgadi, Katarina Carlsson, Agne Larsson, Nuran Ercal, Zheng Zheng Shi, Andreas Winkler, Svante Norgren, Runa Njålsson
Publikováno v:
Biochemical and biophysical research communications. 412(1)
Glutathione (GSH) is present in all mammalian tissues and plays a crucial role in many cellular processes. The second and final step in the synthesis involves the formation of GSH from gamma-glutamylcysteine (γ-GC) and glycine and is catalyzed by gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eb181b5b723ba7306364f0f04f245e
https://pubmed.ncbi.nlm.nih.gov/21802407
https://pubmed.ncbi.nlm.nih.gov/21802407
Autor:
M. Sentís, F. Piñol, J. A. Arranz, Encarnació Riudor, F. Salmerón, M. del Toro, Katarina Carlsson, Ellinor Ristoff, Anders Larsson, R. Alvarez
Publikováno v:
Journal of Inherited Metabolic Disease. 24:404-406
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b027a290d407cc01a19cbf3cd009f6c6
https://doi.org/10.1023/a:1010569021839
https://doi.org/10.1023/a:1010569021839
Autor:
Tuhina Raman, Prayus Tailor, Cheryl Garganta, Runa Njålsson, Hugh B. Carey, Ellinor Ristoff, Katarina Carlsson
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 46(1)
High anion gap metabolic acidosis in adults is a severe metabolic disorder for which the primary organic acid usually is apparent by clinical history and standard laboratory testing. We report a case of recurrent high anion gap metabolic acidosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c4f38abd80973faaa0c431b64955a7
https://pubmed.ncbi.nlm.nih.gov/15983950
https://pubmed.ncbi.nlm.nih.gov/15983950
Publikováno v:
Human mutation. 22(6)
The synthesis of the ubiquitous tripeptide glutathione is impaired in patients with glutathione synthetase deficiency. The defect is inherited in an autosomal recessive manner, and the diagnosis is based on clinical, biochemical, and genetic criteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa6f97947f5222adebbdad6732882b43
https://pubmed.ncbi.nlm.nih.gov/14635114
https://pubmed.ncbi.nlm.nih.gov/14635114
Autor:
Runa NJÅLSSON, Katarina CARLSSON, Birgit OLIN, Birgit CARLSSON, Lel WHITBREAD, Galina POLEKHINA, Michael W. PARKER, Svante NORGREN, Bengt MANNERVIK, Philip G. BOARD, Agne LARSSON
Patients with hereditary glutathione synthetase (GS) (EC 6.3.2.3) deficiency present with variable clinical pictures, presumably related to the nature of the mutations involved. In order to elucidate the relationship between genotype, enzyme function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa72155ab06b1b64524f4f2caf0a3bd
https://europepmc.org/articles/PMC1221148/
https://europepmc.org/articles/PMC1221148/
