Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katarína Kliková"'
Autor:
Peter Racay, Dusan Dobrota, Ivana Pilchova, Jozef Hatok, Katarína Kliková, Andrea Štefaniková
Publikováno v:
Klinicka onkologie. 29:29-38
Heat shock proteins (HSPs) HSP27, HSP70 and HSP90 are molecular chaperones; their expression is increased after exposure of cells to conditions of environmental stress, including heat shock, heavy metals, oxidative stress, or pathologic conditions, s
Publikováno v:
Journal of Molecular Neuroscience. 58:497-506
Both translation arrest and proteasome stress associated with accumulation of ubiquitin-conjugated protein aggregates were considered as a cause of delayed neuronal death after transient global brain ischemia; however, exact mechanisms as well as pos
Autor:
Ivana Pilchova, Peter Racay, Dusan Dobrota, Peter Chudý, Katarína Kliková, Andrea Štefaniková, Juraj Chudej, Jozef Hatok
Publikováno v:
General physiology and biophysics. 34:33-42
Bortezomib (PS-341, or Velcade), reversible inhibitor of 20S proteasome approved for the treatment of multiple myeloma and mantle cell lymphoma, exhibited a cytotoxic effect toward other malignancies including leukaemia. In this study, we have docume
Publikováno v:
General physiology and biophysics. 32:505-516
The aim of presented study was to determine effect of NaBu in combination with ABT-737 on cell survival of leukemic cell line HL-60. In addition, analysis of molecular mechanism of NaBu action with a focus on mitochondrial apoptosis was performed. Bo
Autor:
Peter Racay, Jana Jurečeková, Katarína Kliková, Andrea Štefaniková, Jozef Hatok, Dusan Dobrota
Publikováno v:
Acta Medica Martiniana, Vol 11, Iss 3, Pp 15-23 (2011)
Bcl-2 Family Proteins in Development and Treatment of Malignant DiseasesProteins of Bcl-2 family are key regulators of mitochondrial pathway of apoptosis. Deregulation of apoptosis disrupts the complex and delicate balance between cell proliferation,
Publikováno v:
Toxicology Letters. 180:S104