Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Katarína Drábiková"'
Autor:
Radomír Nosáľ, Zdenko Killinger, Katarína Drábiková, Juraj Payer, Silvia Pažoureková, Viera Jančinová
Publikováno v:
International Immunopharmacology. 69:368-372
The relationship between inflammation and formation of reactive oxygen species (ROS) is still not completely understood and excessive inflammatory reaction is attributed to increased yet also to reduced ROS formation. To compare ROS formation in seve
Autor:
Juraj Harmatha, Jana Pečivová, Katarína Drábiková, Tatiana Mačičková, Tomáš Perečko, Viera Jančinová, Rado Nosáľ
Publikováno v:
Interdisciplinary Toxicology
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 56-60 (2017)
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 56-60 (2017)
In this study we investigated the effect of five therapeutically used drugs and four natural polyphenolic compounds on the mechanism of oxidative burst of human neutrophils concerning their participation in the generation of reactive oxygen species (
Autor:
Marianna Lucová, Jan Šmidrkal, Juraj Harmatha, Katarína Drábiková, Viera Jančinová, Silvia Pažoureková, Radomír Nosál
Publikováno v:
Pharmacology. 97:138-145
Equol (7,4′-dihydroxy-isoflavan, or 4′,7-isoflavandiol) is a chroman derivative produced by intestinal bacteria in response to soy isoflavone intake in some, but not in all, humans. Equol shows strong anti-oxidant, anti-estrogenic, anti-cancerous
Autor:
Radomír Nosáľ, Marianna Lucová, Katarína Drábiková, Tomáš Perečko, Danica Mihalova, Katarína Bauerová, Viera Jančinová, Silvia Pažoureková
Publikováno v:
International Immunopharmacology. 28:175-181
Hydroxychloroquine is used in the therapy of rheumatoid arthritis or lupus erythematosus. Although these diseases are often accompanied by activation of neutrophils, there are still few data relating to the impact of hydroxychloroquine on these cells
Molecular pharmacology of antihistamines in inhibition of oxidative burst of professional phagocytes
Publikováno v:
General physiology and biophysics. 34:209-216
Antihistamines of the H₁and H₃/H₄groups interfere with oxidative burst of human professional phagocytes in vitro. In the concentration of 10 μM, H₁antihistamines of the 1st and 2nd generation inhibited oxidative burst of human neutrophils in
Publikováno v:
Interdisciplinary Toxicology
Prolonged or excessive formation and liberation of cytotoxic substances from neutrophils intensifies inflammation and the risk of tissue damage. From this perspective, administration of substances which are able to reduce activity of neutrophils and
Publikováno v:
Interdisciplinary Toxicology
Reactive oxygen species (ROS) are produced in different metabolic processes including the respiratory burst of neutrophils accompanying local inflammation. The aim of this study was to analyze the effects of N-formyl-methionyl-leucyl-phenylalanine (F
Autor:
Rado Nosál, Klara Svitekova, Katarína Drábiková, Tomáš Pereěko, Juraj Harmatha, Viera Jančinová
Publikováno v:
Pharmacological Reports. 63:790-798
N-feruloylserotonin (N-f-5HT) isomers, isolated from seeds of Leuzea carthamoides (Wild) DC, inhibited dose-dependent oxidative burst in human whole blood and isolated neutrophils in vitro , which were measured by luminol- and/or isoluminol-enhanced
Autor:
Vladimir Knezl, Zuzana Broskova, Ružena Sotníková, Viktor Bauer, Katarína Drábiková, Katalin Szöcs, Štefan Bezek, Jana Navarová, Zuzana Kyseľová, V Kristová, Peter Křenek, Ján Dřímal, Jana Nedelcevova, Iveta Bernatova, Ľudmila Okruhlicová, Viera Nosáľová
Publikováno v:
Interdisciplinary Toxicology
Protection of the vascular endothelium in experimental situationsOne of the factors proposed as mediators of vascular dysfunction observed in diabetes is the increased generation of reactive oxygen species (ROS). This provides support for the use of
Autor:
Viera Jančinová, Katarína Drábiková, Katarína Bauerová, Radomír Nosáľ, Tomáš Perečko, Danica Mihalova
Publikováno v:
Interdisciplinary Toxicology. 4:11-14
Pharmacological regulation of neutrophil activity and apoptosis Novel strategies of antiinflammatory therapy are based upon pharmacological agents capable to enhance the resolution - i.e. the termination of the beneficial inflammation before it may t