Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katalin Balogh-Nemes"'
Autor:
Andrea Bereczki, Judit Tömlo, Katalin Balogh Nemes, Géza Lakner, Mária Tóth, Sándor Drabant, Imre Klebovich, G. Grézal, Bálint Varga
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 41:1354-1359
Tofisopam (1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine) has been shown to be an effective anxiolytic agent in the wide-ranging clinical practice. A high sensitive gas chromatography nitrogen phosphorous detection (GC-
Autor:
Ágnes Szilágyi, József Lengyel, Imre Klebovich, Huba Kalász, Mária Tihanyi, Tibor Szarvas, Katalin Balogh-Nemes
Publikováno v:
Analytical and Bioanalytical Chemistry. 382:760-764
Administration of radiolabelled deprenyl to rats resulted in the urinary elimination of a (14)C-labelled N(epsilon)-monomethyl-lysine. An increased level of N(epsilon)-monomethyl-lysine was found following an oral dose of another drug, also containin
Autor:
Imre Klebovich, Samar Al-Behaisi, M. Abermann, G. Grézal, Katalin Balogh Nemes, Erzsébet Bojti
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:47-51
The pharmacokinetic properties of deramciclane fumarate (EGIS-3886), a new potential anxiolitic agent, and its N-desmethyl metabolite have been investigated in Wistar rats after 10 mg kg−1 deramciclane fumarate was administered orally, intraperiton
Autor:
Emil Mincsovics, Károly Vékey, Katalin Balogh Nemes, Kálmán Újszászy, Imre Klebovich, Tamás Karancsi, Krisztina Ludányi, József Szúnyog
Publikováno v:
Journal of AOAC INTERNATIONAL. 82:231-238
Overpressured layer chromatography was combined with the highly sensitive and rapid digital autoradiography (DAR) and mass spectrometry to separate, detect, and identify 3H-and 14C-labeled deramciclane metabolites in different biological matrixes. Se
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 21:803-818
A gradient RP-HPLC bioanalytical method has been developed for the human pharmacokinetic studies of girisopam, the new 2,3-benzodiazepine compound with anxiolytic effect that has no myorelaxant and anticonvulsive side effects. The compound is an anal
Autor:
Katalin Balogh-Nemes, Zsuzsanna Niegreisz, Andrea Hrabéczy-Páll, George Horvai, Lajos Gödörházy, Antal Tolokán, Viola Horváth, Emilia Kocsi, Imre Klebovich
Publikováno v:
Journal of Chromatography A. 771:35-43
Economic automation of multistep analytical sample preparation is still a largely unsolved problem. Existing systems either handle only a few steps of a complex analytical scheme or they offer a complete solution at relatively high cost. This paper s
Autor:
Imre Klebovich, Katalin Balogh-Nemes, Andrea Egresi, Viola Horváth, George Horvai, Antal Tolokán, Tímea Pap
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 816(1-2)
A highly sensitive high-performance liquid chromatographic-tandem mass spectrometric method (HPLC–MS–MS) has been developed to quantitate clemastine in human plasma for the purpose of pharmacokinetic studies. Sample preparation was carried out by
Autor:
Imre Klebovich, George Horvai, B Gachályi, Harri Kanerva, G. Grézal, Antal Tolokán, Markku Anttila, Sándor Drabant, Viola Horváth, Samar Al-Behaisi, Katalin Balogh Nemes
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 58(3)
The effect of a high-fat meal on the oral bioavailability of deramciclane 30 mg tablet was evaluated in 18 healthy male volunteers in a randomised, single dose, two-way crossover study. The drug was administered following an overnight fast or a stand
Autor:
Imre Klebovich, Viola Horváth, Katalin Balogh Nemes, Andrea Egresi, Antal Tolokán, George Horvai
Publikováno v:
Journal of chromatography. A. 896(1-2)
A rapid and highly sensitive LC-MS-MS method using deuterium-labelled internal standards was developed and evaluated for the simultaneous determination of deramciclane and its pharmacologically active metabolite (N-desmethylderamciclane). The sample
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 698(1-2)
An automated analytical procedure is described for the parallel determination of L-3,4-dihydroxyphenylalanine (levodopa, L-dopa, LD) and the analogous hydrazine compound carbidopa (CD) in dog plasma by ion-pair high-performance liquid chromatography