Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Katalin, E Kövér"'
Autor:
Estefanía Dibello, Natalia Oddone, Jaime Franco, Tünde-Zita Illyés, Andrea Medeiros, Attila Kiss, Fanni Hőgye, Katalin E. Kövér, László Szilágyi, Marcelo A. Comini
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 24, Iss , Pp 100529- (2024)
Earlier evidences showed that diglycosyl diselenides are active against the infective stage of African trypanosomes (top hits IC50 0.5 and 1.5 μM) but poorly selective (selectivity index 38-folds vs. murine and human macrohages). For the glycosyl se
Externí odkaz:
https://doaj.org/article/128999b6d1494de5a7542cec9311668e
Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis
Autor:
Mónika Gönczi, João M. C. Teixeira, Susana Barrera-Vilarmau, Laura Mediani, Francesco Antoniani, Tamás Milán Nagy, Krisztina Fehér, Zsolt Ráduly, Viktor Ambrus, József Tőzsér, Endre Barta, Katalin E. Kövér, László Csernoch, Serena Carra, Monika Fuxreiter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Mef2D context-dependent higher-order assembly controls simultaneous interactions with the basal machinery and the myogenic factors to activate distinct gene expression programs for muscle lineage development.
Externí odkaz:
https://doaj.org/article/c56baa30ca0d43f69074104dd3ee4173
Autor:
Zoltán Kónya, István Tamás, Bálint Bécsi, Beáta Lontay, Mária Raics, István Timári, Katalin E. Kövér, Ferenc Erdődi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4789 (2023)
Identification of specific protein phosphatase-1 (PP1) inhibitors is of special importance regarding the study of its cellular functions and may have therapeutic values in diseases coupled to signaling processes. In this study, we prove that a phosph
Externí odkaz:
https://doaj.org/article/390707bae2ac45368e599b4fb0844f02
Autor:
András Czajlik, Ágnes Batta, Kinga Kerner, Ádám Fizil, Dorottya Hajdu, Mária Raics, Katalin E. Kövér, Gyula Batta
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1208 (2023)
PAF and related antifungal proteins are promising antimicrobial agents. They have highly stable folds around room temperature due to the presence of 3–4 disulfide bonds. However, unfolded states persist and contribute to the thermal equilibrium in
Externí odkaz:
https://doaj.org/article/88fd3eb001674e7e9c43ece79498e7c3
Autor:
Magdolna Csávás, László Kalmár, Petronella Szőke, László Bence Farkas, Bálint Bécsi, Zoltán Kónya, János Kerékgyártó, Anikó Borbás, Ferenc Erdődi, Katalin E. Kövér
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16194 (2022)
The Gram-negative bacterium Pseudomonas aeruginosa is an important opportunistic human pathogen associated with cystic fibrosis. P. aeruginosa produces two soluble lectins, the d-galactose-specific lectin PA-IL (LecA) and the l-fucose-specific lectin
Externí odkaz:
https://doaj.org/article/c6939a870a194adeb8cb1a85ae338efe
Publikováno v:
ChemistryOpen, Vol 8, Iss 8, Pp 1048-1051 (2019)
Abstract It is shown how the resolution in SEA XLOC NMR spectra for distinguishing between heteronuclear two‐ and three‐bond correlations for all 13C multiplicities can be improved by a modified experiment delivering absorptive profiles in the in
Externí odkaz:
https://doaj.org/article/60bba7bdd50d40938a799d0f9b3c7be1
Autor:
Zoltán Kónya, Bálint Bécsi, Andrea Kiss, Dániel Horváth, Mária Raics, Katalin E. Kövér, Beáta Lontay, Ferenc Erdődi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 500-509 (2019)
Several ellagitannins inhibited the activity of protein phosphatase-1 (PP1) and -2 A (PP2A) catalytic subunits (PP1c and PP2Ac) with preferential suppression of PP1c over PP2Ac. The inhibitory potency for PP1c followed the order of tellimagrandin I >
Externí odkaz:
https://doaj.org/article/1ebea239b38c40f89067b205d3226b25
Autor:
Mária Raics, Álex Kálmán Balogh, Chandan Kishor, István Timári, Francisco J. Medrano, Antonio Romero, Rob Marc Go, Helen Blanchard, László Szilágyi, Katalin E. Kövér, Krisztina Fehér
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2494 (2022)
Human galectin-3 (hGal-3) is involved in a variety of biological processes and is implicated in wide range of diseases. As a result, targeting hGal-3 for clinical applications has become an intense area of research. As a step towards the development
Externí odkaz:
https://doaj.org/article/bba1f734af9a4b28a32f126b4856deee
Autor:
Ilona Bereczki, Zsolt Szűcs, Gyula Batta, Tamás Milán Nagy, Eszter Ostorházi, Katalin E. Kövér, Anikó Borbás, Pál Herczegh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 77 (2022)
Various dimeric derivatives of the glycopeptide antibiotic teicoplanin were prepared with the aim of increasing the activity of the parent compound against glycopeptide-resistant bacteria, primarily vancomycin-resistant enterococci. Starting from tei
Externí odkaz:
https://doaj.org/article/3da40169d3d543cc84a3002057ef95a6
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 201 (2022)
Detailed investigation of ligand–protein interactions is essential for better understanding of biological processes at the molecular level. Among these binding interactions, the recognition of glycans by lectins is of particular importance in sever
Externí odkaz:
https://doaj.org/article/1f482511a2b9474795cc40d6d66421e8