Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Single cell regulatory architecture of human pancreatic islets suggests sex differences in β cell function and the pathogenesis of type 2 diabetes.

Autor: Qadir MMF; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.; Southeast Louisiana Veterans Health Care System, New Orleans, LA, USA.; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA, USA., Elgamal RM; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA.; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Song K; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Kudtarkar P; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Sakamuri SSVP; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Katakam PV; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., El-Dahr SS; Department of Pediatrics, Tulane University, School of Medicine, New Orleans, LA, USA., Kolls JK; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Gaulton KJ; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Mauvais-Jarvis F; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA.; Southeast Louisiana Veterans Health Care System, New Orleans, LA, USA.; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA, USA.

Publikováno v: Research square [Res Sq] 2024 Jul 03. Date of Electronic Publication: 2024 Jul 03.

Urinary Angiotensinogen Displays Sexual Dimorphism in Non-Diabetic Humans and Mice with Overweight.

Autor: Gonzalez AA; Instituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340025, Chile., Visniauskas B; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Reverte V; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA., Sure VN; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Vallotton Z; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA., Torres BS; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA., Acosta MA; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA., Zemedkun M; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA., Katakam PV; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Prieto MC; Department of Physiology and Hypertension Core, Tulane University School of Medicine, New Orleans, LA 70112, USA.; Renal and Hypertension Center of Excellence, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells.

Autor: Xu W; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA 70119, USA., Qadir MMF; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA 70119, USA; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA 70112, USA., Nasteska D; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Mota de Sa P; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA 70119, USA; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA 70112, USA., Gorvin CM; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Blandino-Rosano M; Department of Internal Medicine, Division Endocrinology, Metabolism and Diabetes, Miller School of Medicine, University of Miami, Miami, FL 33136, USA., Evans CR; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Ho T; Department of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI, USA., Potapenko E; Department of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI, USA., Veluthakal R; Department of Molecular and Cellular Endocrinology, City of Hope Beckman Research Institute, Duarte, CA 91010, USA., Ashford FB; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Bitsi S; Division of Diabetes, Endocrinology & Metabolism, Section of Cell Biology and Functional Genomics, Imperial College London, London SW7 2AZ, UK., Fan J; Center for Cellular and Molecular Diagnostics, Department of Molecular & Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Bhondeley M; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA 70119, USA; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA 70112, USA., Song K; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA., Sure VN; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Sakamuri SSVP; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Schiffer L; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Beatty W; Molecular Imaging Facility, Washington University School of Medicine, St. Louis, MO 63110, USA., Wyatt R; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Frigo DE; Departments of Cancer Systems Imaging and Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA., Liu X; Division of Biomedical Informatics and Genomics, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA., Katakam PV; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Arlt W; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK; National Institute for Health Research Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham B15 2TH, UK., Buck J; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10021, USA., Levin LR; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10021, USA., Hu T; Center for Cellular and Molecular Diagnostics, Department of Molecular & Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA., Kolls J; Center for Translational Research in Infection and Inflammation, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA., Burant CF; Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Tomas A; Division of Diabetes, Endocrinology & Metabolism, Section of Cell Biology and Functional Genomics, Imperial College London, London SW7 2AZ, UK., Merrins MJ; Department of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of Wisconsin-Madison, Madison, WI, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Thurmond DC; Department of Molecular and Cellular Endocrinology, City of Hope Beckman Research Institute, Duarte, CA 91010, USA., Bernal-Mizrachi E; Department of Internal Medicine, Division Endocrinology, Metabolism and Diabetes, Miller School of Medicine, University of Miami, Miami, FL 33136, USA., Hodson DJ; Institute of Metabolism and Systems Research and Centre for Membrane Proteins and Receptors, University of Birmingham, Birmingham B15 2TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TT, UK., Mauvais-Jarvis F; Section of Endocrinology and Metabolism, John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA; Southeast Louisiana Veterans Health Care System, New Orleans, LA 70119, USA; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA 70112, USA. Electronic address: fmauvais@tulane.edu.

Publikováno v: Cell reports [Cell Rep] 2023 May 30; Vol. 42 (5), pp. 112529. Date of Electronic Publication: 2023 May 17.

Aging related impairment of brain microvascular bioenergetics involves oxidative phosphorylation and glycolytic pathways.

Autor: Sakamuri SS; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Sure VN; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Kolli L; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Evans WR; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA.; Neuroscience Program, Tulane Brain Institute, Tulane University, New Orleans, LA, USA., Sperling JA; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Bix GJ; Neuroscience Program, Tulane Brain Institute, Tulane University, New Orleans, LA, USA.; Clinical Neuroscience Research Center, New Orleans, LA, USA., Wang X; Neuroscience Program, Tulane Brain Institute, Tulane University, New Orleans, LA, USA.; Clinical Neuroscience Research Center, New Orleans, LA, USA., Atochin DN; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA., Murfee WL; J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA., Mostany R; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA.; Neuroscience Program, Tulane Brain Institute, Tulane University, New Orleans, LA, USA., Katakam PV; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA.; Neuroscience Program, Tulane Brain Institute, Tulane University, New Orleans, LA, USA.; Clinical Neuroscience Research Center, New Orleans, LA, USA.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 Aug; Vol. 42 (8), pp. 1410-1424. Date of Electronic Publication: 2022 Mar 16.