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pro vyhledávání: '"Kat S Moore"'
Autor:
Kat S Moore, Nurcan Yagci, Floris van Alphen, Alexander B Meijer, Peter A C 't Hoen, Marieke von Lindern
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201690 (2018)
Erythropoiesis is regulated at many levels, including control of mRNA translation. Changing environmental conditions, such as hypoxia or the availability of nutrients and growth factors, require a rapid response enacted by the enhanced or repressed t
Externí odkaz:
https://doaj.org/article/0883173db7f541bc9f4c973ca5e2d93b
Autor:
Nahuel A Paolini, Kat S Moore, Franca M di Summa, Ivo F A C Fokkema, Peter A C 't Hoen, Marieke von Lindern
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0193790 (2018)
The regulation of translation initiation factor 2 (eIF2) is important for erythroid survival and differentiation. Lack of iron, a critical component of heme and hemoglobin, activates Heme Regulated Inhibitor (HRI). This results in phosphorylation of
Externí odkaz:
https://doaj.org/article/a59e16ce00ad4e449689df39c3c646a2
Autor:
Marte C. Liefaard, Kat S. Moore, Lennart Mulder, Daan van den Broek, Jelle Wesseling, Gabe S. Sonke, Lodewyk F. A. Wessels, Matti Rookus, Esther H. Lips
Publikováno v:
BJC: British Journal of Cancer, 128(8)
Background Studies have shown that blood platelets contain tumour-specific mRNA profiles tumour-educated platelets (TEPs). Here, we aim to train a TEP-based breast cancer detection classifier. Methods Platelet mRNA was sequenced from 266 women with s
Autor:
Peter A C 't Hoen, Kat S. Moore
Publikováno v:
Journal of Biological Chemistry, 294, 1, pp. 1-9
Journal of Biological Chemistry, 294, 1-9
Journal of Biological Chemistry, 294, 1-9
Contains fulltext : 202642.pdf (Publisher’s version ) (Open Access) RNA-binding proteins (RBPs) play important roles in the control of gene expression and the coordination of different layers of post-transcriptional regulation. Interactions between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6147d8a3f13f75e71386e50b1a2edd2
https://hdl.handle.net/2066/202642
https://hdl.handle.net/2066/202642
Autor:
Marieke von Lindern, Kat S. Moore
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology
Control of gene expression in erythropoiesis has to respond to signals that may emerge from intracellular processes or environmental factors. Control of mRNA translation allows for relatively rapid modulation of protein synthesis from the existing tr
Autor:
Marieke von Lindern, Nurcan Yagci, Alexander B. Meijer, Rastislav Horos, Ntsiki M. Held, Riekelt H. Houtkooper, Nahuel A. Paolini, Peter A C 't Hoen, Kat S. Moore, Emile van den Akker, Floris P. J. van Alphen
Expression of the RNA-binding protein Csde1 (Cold shock domain protein e1) is strongly upregulated during erythropoiesis compared to other hematopoietic lineages. In the severe congenital anemia Diamond Blackfan Anemia (DBA), however, Csde1 expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfed78276e2c38224187ec58b08da2d
https://doi.org/10.1101/203497
https://doi.org/10.1101/203497
Publikováno v:
Journal of leukocyte biology, 102(4), 1035-1054. FASEB
Journal of Leukocyte Biology, 102(4), 1035-1054. FASEB
Zaal, A, Nota, B, Moore, K S, Dieker, M, van Ham, S M & Ten Brinke, A 2017, ' TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors ', Journal of Leukocyte Biology, vol. 102, no. 4, pp. 1035-1054 . https://doi.org/10.1189/jlb.2MA0217-058R
Journal of Leukocyte Biology, 102(4), 1035-1054. FASEB
Zaal, A, Nota, B, Moore, K S, Dieker, M, van Ham, S M & Ten Brinke, A 2017, ' TLR4 and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2, PI3Kβ, SGK1, and FOXO transcription factors ', Journal of Leukocyte Biology, vol. 102, no. 4, pp. 1035-1054 . https://doi.org/10.1189/jlb.2MA0217-058R
Crosstalk between complement component 5a receptors (C5aRs) and TLRs in dendritic cells (DCs) occurs upon pathogen invasion; however, studies on C5aR and TLR crosstalk mainly focused on the modulating effect of C5a on TLR-induced cytokine production.
Autor:
Kat S. Moore, Marieke von Lindern
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Control of gene expression in erythropoiesis has to respond to signals that may emerge from intracellular processes or environmental factors. Control of mRNA translation allows for relatively rapid modulation of protein synthesis from the existing tr
Externí odkaz:
https://doaj.org/article/c89b2d7ebf8449199894138a03526867