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Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia.

Autor: Rodems BJ; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA., Sharma S; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA., Baker CD; Genomics Research Center, University of Rochester Medical Center, Rochester, NY 14642, USA., Kaszuba CM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.; Department of Biomedical Engineering, University of Rochester, Rochester, NY 14642, USA., Ito T; Department of Bioscience and Technology, Graduate School of Bioscience and Technology, Fukui Prefectural University, Fukui, Japan., Liesveld JL; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.; Division of Hematology and Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA., Calvi LM; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.; Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA., Becker MW; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.; Division of Hematology and Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA., Jordan CT; Division of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Ashton JM; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.; Genomics Research Center, University of Rochester Medical Center, Rochester, NY 14642, USA., Bajaj J; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 14. Date of Electronic Publication: 2024 May 14.