Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kasyoka, Kilonzo"'
Autor:
Kasyoka Kilonzo, Daniel Strahnen, Vivien Prex, John Gems, Bastiaan van der Veen, Sampath K. T. Kapanaiah, Bhargavi K. B. Murthy, Stefanie Schulz, Rolf Sprengel, David Bannerman, Dennis Kätzel
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Schizophrenia is associated with a broad range of severe and currently pharmacoresistant cognitive deficits. Prior evidence suggests that hypofunction of AMPA-type glutamate receptors (AMPARs) containing the subunit GLUA1, encoded by GRIA1,
Externí odkaz:
https://doaj.org/article/5b41206531d5432aa8c18a49690a5e52
Autor:
Bastiaan van der Veen, Sampath K. T. Kapanaiah, Kasyoka Kilonzo, Peter Steele-Perkins, Martin M. Jendryka, Stefanie Schulz, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Thomas Akam, Janet R. Nicholson, Birgit Liss, Wiebke Nissen, Anton Pekcec, Dennis Kätzel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
In order to identify receptors that may serve as therapeutic targets in the treatment of impulse control disorders, van der Veen et al developed a systematic target discovery approach combining behavioural chemogenetics and gene expression analysis.
Externí odkaz:
https://doaj.org/article/cd48bdbae6944aca8dc5ad44ab6da068
Autor:
Kasyoka Kilonzo, Bastiaan van der Veen, Jasper Teutsch, Stefanie Schulz, Sampath K. T. Kapanaiah, Birgit Liss, Dennis Kätzel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract A hypofunction of N-methyl-D-aspartate glutamate receptors (NMDARs) has been implicated in the pathogenesis of schizophrenia by clinical and rodent studies. However, to what extent NMDAR-hypofunction in distinct cell-types across the brain c
Externí odkaz:
https://doaj.org/article/34948e7f5a9c4290958085c57becf0fc
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Hypofunction of N-methyl-D-aspartate glutamate receptors (NMDARs), whether caused by endogenous factors like auto-antibodies or mutations, or by pharmacological or genetic manipulations, produces a wide variety of deficits which overlap with—but do
Externí odkaz:
https://doaj.org/article/9154faad51d240af972f598e0bfb0f0c
Publikováno v:
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-12 (2017)
Abstract Background Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping. Measuring homecage-activity with standard and cost-effective optical methods in mice has be
Externí odkaz:
https://doaj.org/article/22042c37bd104d738de5b15ad0bdc311
Autor:
Kasyoka Kilonzo, Daniel Strahnen, Vivien Prex, John Gems, Bastiaan van der Veen, Sampath K. T. Kapanaiah, Bhargavi K. B. Murthy, Stefanie Schulz, Rolf Sprengel, David Bannerman, Dennis Kätzel
Publikováno v:
Translational psychiatry. 12(1)
Schizophrenia is associated with a broad range of severe and currently pharmacoresistant cognitive deficits. Prior evidence suggests that hypofunction of AMPA-type glutamate receptors (AMPARs) containing the subunit GLUA1, encoded by GRIA1, might be
Autor:
Bastiaan, van der Veen, Sampath K T, Kapanaiah, Kasyoka, Kilonzo, Peter, Steele-Perkins, Martin M, Jendryka, Stefanie, Schulz, Bosiljka, Tasic, Zizhen, Yao, Hongkui, Zeng, Thomas, Akam, Janet R, Nicholson, Birgit, Liss, Wiebke, Nissen, Anton, Pekcec, Dennis, Kätzel
Publikováno v:
Communications Biology
Pathological impulsivity is a debilitating symptom of multiple psychiatric diseases with few effective treatment options. To identify druggable receptors with anti-impulsive action we developed a systematic target discovery approach combining behavio
Autor:
Ayse Yarali, Archana Durairaja, Vignesh Viswanathan, Anne Voigt, Mathangi Ganesan, Kasyoka Kilonzo, Christian König, Emmanuel Antwi-Adjei
Publikováno v:
The journal of experimental biology, 220: 1548-1553
The Journal of Experimental Biology
The Journal of Experimental Biology
Avoiding associatively learned predictors of danger is crucial for survival. Aversive memories can, however, become counter-adaptive when they are overly generalized to harmless cues and contexts. In a fruit fly odor–electric shock associative memo
Publikováno v:
JOURNAL OF BIOLOGICAL ENGINEERING
Journal of Biological Engineering
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-12 (2017)
Journal of Biological Engineering
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-12 (2017)
Background Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping. Measuring homecage-activity with standard and cost-effective optical methods in mice has become diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04f85701b11825de2d07189d250dfd2
https://hdl.handle.net/21.11116/0000-0001-84E6-621.11116/0000-0001-84E8-4
https://hdl.handle.net/21.11116/0000-0001-84E6-621.11116/0000-0001-84E8-4