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pro vyhledávání: '"Kasutomo Imahori"'
Autor:
Miyuki Murayama, Kasutomo Imahori, Yuko Nakazato, Marc Mercken, Kazuki Sato, Toshiyuki Honda, Akihiko Takashima, Hiroshi Takahashi, Kaori Noguchi
Publikováno v:
FEBS letters. 389(3)
The majority of cases of early-onset familial Alzheimer disease are caused by mutations in the recently identified presenilin 1 (PS1) gene, located on chromosome 14. PS1, a 467 amino acid protein, is predicted to be an integral membrane protein conta