The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes

Autor: Sette, A., Vitiello, A., Reherman, B., Fowler, P., Nayersina, R., Kast, W. M., Melief, C. J. M., Oseroff, C., Yuan, L., Ruppert, J., Sidney, J., Del Guercio, M. -F, Southwood, S., Kubo, R. T., Chesnut, R. W., Grey, H. M., Francis Chisari

Publikováno v: Scopus-Elsevier

The relationship between binding affinity for HLA class I molecules and immunogenicity of discrete peptide epitopes has been analyzed in two different experimental approaches. In the first approach, the immunogenicity of potential epitopes ranging in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034c91a9e7d44fc5b616feb006a147d5
https://doi.org/10.4049/jimmunol.153.12.5586

In vivo detection of fluorescent tumor-specific cytotoxic T cell clones

Autor: Toes, R E, den Haan, J M, Feltkamp, M C, Blom, Ria J, Melief, C J, Claassen, E, Kast, W M

Publikováno v: Journal of Immunological Methods, 163(1), 23-32. Elsevier
Toes, R E, den Haan, J M, Feltkamp, M C, Blom, R J, Melief, C J, Claassen, E & Kast, W M 1993, ' In vivo detection of fluorescent tumor-specific cytotoxic T cell clones ', Journal of Immunological Methods, vol. 163, no. 1, pp. 23-32 .

Cytotoxic T lymphocytes (CTL) can be very effective mediators of tumor-specific immunity in vivo. Since little is known about the in vivo behaviour of cultured tumor-specific CTL, a fast and simple method has been developed utilizing a lipophilic car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e95fab3eec327e19dc32ec0549e13994
https://research.vumc.nl/en/publications/18abfca3-d274-4d57-8958-f230c57ac949

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Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells.

Autor: Song, L L, Peng, Y, Yun, J, Rizzo, P, Chaturvedi, V, Weijzen, S, Kast, W M, Stone, P J B, Santos, L, Loredo, A, Lendahl, U, Sonenshein, G, Osborne, B, Qin, J-Z, Pannuti, A, Nickoloff, B J, Miele, L

Publikováno v: Oncogene; 10/2/2008, Vol. 27 Issue 44, p5833-5844, 12p, 1 Color Photograph, 1 Black and White Photograph, 5 Graphs

Effects of TGF-beta on the immune system: implications for cancer immunotherapy.

Autor: de Visser, K E, Kast, W M

Publikováno v: Leukemia (08876924); Aug99, Vol. 13 Issue 8, p1188-1199, 12p