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pro vyhledávání: '"Kassie S. Manning"'
Publikováno v:
ACS Chemical Biology. 12:2503-2509
Myotonic dystrophy type 1 (DM1) is a multisystemic disease caused by an expanded CTG repeat in the 3′ UTR of the dystrophia myotonica protein kinase (DMPK) gene. Short, DNA-based antisense oligonucleotides termed gapmers are a promising strategy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dac0bad33c6271a64eb3d6b971a5316b
https://doi.org/10.1021/acschembio.7b00416
https://doi.org/10.1021/acschembio.7b00416
Publikováno v:
ACS chemical biology. 12(10)
Myotonic dystrophy type 1 (DM1) is a multisystemic disease caused by an expanded CTG repeat in the 3′ UTR of the dystrophia myotonica protein kinase (DMPK) gene. Short, DNA-based antisense oligonucleotides termed gapmers are a promising strategy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70f743dd68ab8b08234bc4074953fabb
https://pubmed.ncbi.nlm.nih.gov/28853853
https://pubmed.ncbi.nlm.nih.gov/28853853
Autor:
Thomas A. Cooper, Kassie S. Manning
Publikováno v:
Nature reviews. Molecular cell biology. 18(2)
A goal of human genetics studies is to determine the mechanisms by which genetic variation produces phenotypic differences that affect human health. Efforts in this respect have previously focused on genetic variants that affect mRNA levels by alteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8ac5596d263bf320b37cd6000f9b71
https://pubmed.ncbi.nlm.nih.gov/27847391
https://pubmed.ncbi.nlm.nih.gov/27847391