Výsledky vyhledávání - "Kasse Skagen"

Akademický článek

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function

Autor: Alison E. Fohner, Rachel Dalton, Kasse Skagen, Konner Jackson, Katrina G. Claw, Scarlett E. Hopkins, Renee Robinson, Burhan A. Khan, Bhagwat Prasad, Erin G. Schuetz, Deborah A. Nickerson, Timothy A. Thornton, Denise A. Dillard, Bert B. Boyer, Kenneth E. Thummel, Erica L. Woodahl

Publikováno v: Clinical and Translational Science, Vol 14, Iss 4, Pp 1292-1302 (2021)

Abstract The frequencies of genetic variants in the CYP3A4 and CYP3A5 genes differ greatly across global populations, leading to profound differences in the metabolic activity of these enzymes and resulting drug metabolism rates, with important conse

Externí odkaz: https://doaj.org/article/18c815b78eaf46c482f67ddc2280dfe6

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Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function

Autor: Renee F. Robinson, Burhan Khan, Katrina G. Claw, Alison E. Fohner, Kenneth E. Thummel, Erin G. Schuetz, Scarlett E. Hopkins, Erica L. Woodahl, Kasse Skagen, Denise A. Dillard, Konner Jackson, Timothy A. Thornton, Bhagwat Prasad, Rachel Dalton, Bert B. Boyer, Deborah A. Nickerson

Publikováno v: Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 4, Pp 1292-1302 (2021)

The frequencies of genetic variants in the CYP3A4 and CYP3A5 genes differ greatly across global populations, leading to profound differences in the metabolic activity of these enzymes and resulting drug metabolism rates, with important consequences f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f1285c9d8ab5ab0ed6a9e925a2a584
http://europepmc.org/articles/PMC8301563

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P-Glycoprotein Transport of Neurotoxic Pesticides

Autor: Rachel Dalton, Kasse Skagen, Sarah E. Lacher, Erica L. Woodahl, J. Veit

P-glycoprotein (P-gp) has been associated with a number of neurodegenerative diseases, including Parkinson's disease, although the mechanisms remain unclear. Altered transport of neurotoxic pesticides has been proposed in Parkinson's disease, but it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21775db638adcd38af561c3ecaafb06f
https://europepmc.org/articles/PMC4576670/

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