Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kassandra J. Naughton"'
Autor:
Fan Chen, Aria L. Byrd, Jinpeng Liu, Robert M. Flight, Tanner J. DuCote, Kassandra J. Naughton, Xiulong Song, Abigail R. Edgin, Alexsandr Lukyanchuk, Danielle T. Dixon, Christian M. Gosser, Dave-Preston Esoe, Rani D. Jayswal, Stuart H. Orkin, Hunter N. B. Moseley, Chi Wang, Christine Fillmore Brainson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Delineating the specific role of Polycomb Repressive Complex 2 (PRC2) in various cancer systems is desirable as inhibitors for EZH2 inhibitors are approved for some cancers. Here the authors show haplo- and full-insufficiency of EZH2 drive divergent
Externí odkaz:
https://doaj.org/article/2cf8d2a337944addaaca421358a1cc3b
Autor:
Aria L. Byrd, Xufeng Qu, Alexsandr Lukyanchuk, Jinpeng Liu, Fan Chen, Kassandra J. Naughton, Tanner J. DuCote, Xiulong Song, Hannah C. Bowman, Yanming Zhao, Abigail R. Edgin, Chi Wang, Jinze Liu, Christine Fillmore Brainson
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 289-304 (2023)
Summary: Aberrant lung cell differentiation is a hallmark of many lung diseases including chronic obstructive pulmonary disease (COPD). The EZH2-containing Polycomb Repressive Complex 2 (PRC2) regulates embryonic lung stem cell fate, but its role in
Externí odkaz:
https://doaj.org/article/7cf07165ad8e439a85b6c1a91f2b25ef
Autor:
Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R. Edgin, Xiulong Song, Haikuo Zhang, Kwok‐Kin Wong, Hunter N. B. Moseley, Chi Wang, Christine F. Brainson
Publikováno v:
Advanced Science, Vol 8, Iss 22, Pp n/a-n/a (2021)
Abstract Targeting the epidermal growth factor receptor (EGFR) with tyrosine kinase inhibitors (TKIs) is one of the major precision medicine treatment options for lung adenocarcinoma. Due to common development of drug resistance to first‐ and secon
Externí odkaz:
https://doaj.org/article/1d70799b294842b6a8cf3f7bd6a3471b
Autor:
Tanner J. DuCote, Kassandra J. Naughton, Erika M. Skaggs, Therese J. Bocklage, Derek B. Allison, Christine F. Brainson
Publikováno v:
Laboratory Investigation. :100176