Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kaspers, G. J.L."'
Autor:
Blokker, R. S., Smit, L. M.E., Van Den Bos, C., Overberg, P. C., Caron, H. N., Kaspers, G. J.L.
Publikováno v:
Nederlands Tijdschrift voor Geneeskunde, 150(14), 799-803. Bohn Stafleu van Loghum
Nederlands tijdschrift voor geneeskunde, 150(14), 799-803. Bohn Stafleu van Loghum
Blokker, R S, Smit, L M E, Van Den Bos, C, Overberg, P C, Caron, H N & Kaspers, G J L 2006, ' Een jongen met acute cerebellaire ataxie zonder opsoclonus, door een neuroblastoom ', Nederlands Tijdschrift voor Geneeskunde, vol. 150, no. 14, pp. 799-803 .
Nederlands tijdschrift voor geneeskunde, 150(14), 799-803. Bohn Stafleu van Loghum
Blokker, R S, Smit, L M E, Van Den Bos, C, Overberg, P C, Caron, H N & Kaspers, G J L 2006, ' Een jongen met acute cerebellaire ataxie zonder opsoclonus, door een neuroblastoom ', Nederlands Tijdschrift voor Geneeskunde, vol. 150, no. 14, pp. 799-803 .
A 2-year-old boy presented with acute cerebellar ataxia without opsoclonus. The ataxia was assumed to be post-viral. After a period of 2 years a neuroblastoma was detected. Treatment with a curative intent was successful and consisted of metaiodobenz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2e5ed1e5f93d6b38c2e28819bab6c0b
https://research.vumc.nl/en/publications/1a5a90da-e459-47a8-b542-cecb14aa90e5
https://research.vumc.nl/en/publications/1a5a90da-e459-47a8-b542-cecb14aa90e5
Autor:
Stam, R. W., Hubeek, I., den Boer, M. L., Buijs-Gladdines, J. G.C.A.M., Creutzig, U., Kaspers, G. J.L., Pieters, R.
Publikováno v:
Leukemia, 20(1), 179-182. Nature Publishing Group
Stam, R W, Hubeek, I, den Boer, M L, Buijs-Gladdines, J G C A M, Creutzig, U, Kaspers, G J L & Pieters, R 2006, ' MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia [20] ', Leukemia, vol. 20, no. 1, pp. 179-182 . https://doi.org/10.1038/sj.leu.2404031
Stam, R W, Hubeek, I, den Boer, M L, Buijs-Gladdines, J G C A M, Creutzig, U, Kaspers, G J L & Pieters, R 2006, ' MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia [20] ', Leukemia, vol. 20, no. 1, pp. 179-182 . https://doi.org/10.1038/sj.leu.2404031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e56ba62833f8b78032e92cdca7a446b0
https://research.vumc.nl/en/publications/c09be7a7-69bf-4bd9-8de2-546d7e461b47
https://research.vumc.nl/en/publications/c09be7a7-69bf-4bd9-8de2-546d7e461b47
Autor:
Hubeek, I., Stam, R. W., Peters, G. J., Broekhuizen, R., Meijerink, J. P.P., Van Wering, E. R., Gibson, B. E.S., Creutzig, U., Zwaan, C. M., Cloos, J., Kuik, D. J., Pieters, R., Kaspers, G. J.L.
Publikováno v:
Hubeek, I, Stam, R W, Peters, G J, Broekhuizen, R, Meijerink, J P P, Van Wering, E R, Gibson, B E S, Creutzig, U, Zwaan, C M, Cloos, J, Kuik, D J, Pieters, R & Kaspers, G J L 2005, ' The human equilibrative nucleoside transporter I mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia ', British Journal of Cancer, vol. 93, no. 12, pp. 1388-1394 . https://doi.org/10.1038/sj.bjc.6602881
British Journal of Cancer, 93(12), 1388-1394. Nature Publishing Group
British Journal of Cancer, 93(12), 1388-1394. Nature Publishing Group
Cytarabine (ara-C) is the most effective agent for the treatment of acute myeloid leukaemia (AML). Aberrant expression of enzymes involved in the transport/metabolism of ara-C could explain drug resistance. We determined mRNA expression of these fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::358cc418a50506f06813d98470a1a723
https://research.vumc.nl/en/publications/4ad873dd-d387-40c8-ae3c-1307d85d1c6a
https://research.vumc.nl/en/publications/4ad873dd-d387-40c8-ae3c-1307d85d1c6a
Autor:
Creutzig, U., Kaspers, G. J.L.
Publikováno v:
Journal of Clinical Oncology, 22(16), 3432-3433. American Society of Clinical Oncology
Creutzig, U & Kaspers, G J L 2004, ' Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia [3] ', Journal of Clinical Oncology, vol. 22, no. 16, pp. 3432-3433 . https://doi.org/10.1200/JCO.2004.99.116
Creutzig, U & Kaspers, G J L 2004, ' Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia [3] ', Journal of Clinical Oncology, vol. 22, no. 16, pp. 3432-3433 . https://doi.org/10.1200/JCO.2004.99.116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a4da56620cf4861c0ae34fb56c935413
https://research.vumc.nl/en/publications/6fc9fe0f-0952-4e09-8883-569b797e0e61
https://research.vumc.nl/en/publications/6fc9fe0f-0952-4e09-8883-569b797e0e61
Autor:
De Haas, V., Kaspers, G. J.L., Oosten, L., Bresters, D., Pieters, R., Van Der Velden, V. H.J., Van Wering, E. R., Van Den Berg, H., Van Der Schoot, C. E.
Publikováno v:
De Haas, V, Kaspers, G J L, Oosten, L, Bresters, D, Pieters, R, Van Der Velden, V H J, Van Wering, E R, Van Den Berg, H & Van Der Schoot, C E 2002, ' Is there a relationship between in vitro drug resistance and level of minimal residual disease as detected by polymerase chain reaction at the end of induction therapy in childhood acute lymphoblastic leukaemia? [1] ', British Journal of Haematology, vol. 118, no. 4, pp. 1190-1191 . https://doi.org/10.1046/j.1365-2141.2002.36211.x
British Journal of Haematology, 118(4), 1190-1191. Wiley-Blackwell
British Journal of Haematology, 118(4), 1190-1191. Wiley-Blackwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a3c9d8c493e1742eeccb84065a0326b6
https://research.vumc.nl/en/publications/29bad8e6-bcb9-429f-a4c7-bf8e03a4400b
https://research.vumc.nl/en/publications/29bad8e6-bcb9-429f-a4c7-bf8e03a4400b
Autor:
Taub, J. W., Matherly, L. H., Ravindranath, Y., Kaspers, G. J.L., Rots, M. G., van Zantwijk, C. H.
Publikováno v:
Leukemia, 16(4), 764-765. Nature Publishing Group
Taub, J W, Matherly, L H, Ravindranath, Y, Kaspers, G J L, Rots, M G & van Zantwijk, C H 2002, ' Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia [2] ', Leukemia, vol. 16, no. 4, pp. 764-765 . https://doi.org/10.1038/sj.leu.2402428
Taub, J W, Matherly, L H, Ravindranath, Y, Kaspers, G J L, Rots, M G & van Zantwijk, C H 2002, ' Polymorphisms in methylenetetrahydrofolate reductase and methotrexate sensitivity in childhood acute lymphoblastic leukemia [2] ', Leukemia, vol. 16, no. 4, pp. 764-765 . https://doi.org/10.1038/sj.leu.2402428
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::052291f1746ce9d76078c2e2bf53a934
https://research.vumc.nl/en/publications/f98d71e9-3cc8-4832-829e-cd0f5b6df9c5
https://research.vumc.nl/en/publications/f98d71e9-3cc8-4832-829e-cd0f5b6df9c5
Autor:
Zwaan, C. M., Kaspers, G. J.L., Pieters, R., Ramakers-Van Woerden, N. L., Den Boer, M. L., Wunsche, R., Rottier, M. M.A., Hahlen, K., Van Wering, E. R., Janka-Schaub, G. E., Creutzig, U., Veerman, A. J.P.
Publikováno v:
Zwaan, C M, Kaspers, G J L, Pieters, R, Ramakers-Van Woerden, N L, Den Boer, M L, Wunsche, R, Rottier, M M A, Hahlen, K, Van Wering, E R, Janka-Schaub, G E, Creutzig, U & Veerman, A J P 2000, ' Cellular drug resistance profiles in childhood acute myeloid leukemia : Differences between FAB types and comparison with acute lymphoblastic leukemia ', Blood, vol. 96, no. 8, pp. 2879-2886 .
Determining in vitro drug resistance may reveal clinically relevant information in childhood leukemia. Using the methylthiazol-tetrezolium assay, the resistance of untreated leukemic cells to 21 drugs was compared in 128 children with acute myeloid l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10172::aff6e18fcdbaede1579e5a9a0cec610b
https://research.vumc.nl/en/publications/2a693a95-f531-4569-a1a2-5d8297a1ddb8
https://research.vumc.nl/en/publications/2a693a95-f531-4569-a1a2-5d8297a1ddb8
Autor:
Dübbers, A., Würthwein, G., Müller, H. J., Schulze-Westhoff, P., Winkelhorst, M., Kurzknabe, E., Lanvers, C., Pieters, R., Kaspers, G. J.L., Creutzig, U., Ritter, J., Boos, J.
Publikováno v:
Dübbers, A, Würthwein, G, Müller, H J, Schulze-Westhoff, P, Winkelhorst, M, Kurzknabe, E, Lanvers, C, Pieters, R, Kaspers, G J L, Creutzig, U, Ritter, J & Boos, J 2000, ' Asparagine synthetase activity in paediatric acute leukaemias : AML-M5 subtype shows lowest activity ', British Journal of Haematology, vol. 109, no. 2, pp. 427-429 . https://doi.org/10.1046/j.1365-2141.2000.02015.x
British Journal of Haematology, 109(2), 427-429. Wiley-Blackwell
British Journal of Haematology, 109(2), 427-429. Wiley-Blackwell
Lack of sufficient cellular activity of asparagine synthetase (AS) in blast cells compared with normal tissue is thought to be the basis of the antileukaemic effect of L-asparaginase in acute lymphoblastic leukaemia (ALL). Although L-asparaginase is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::93e4608eb160f37e6dd9133ce4143fd6
https://research.vumc.nl/en/publications/49285e6b-0e14-4744-bf2f-d93e7388bbfb
https://research.vumc.nl/en/publications/49285e6b-0e14-4744-bf2f-d93e7388bbfb
Autor:
Pieters, R., Pongers-Willemse, M. J., Den Boer, M. L., Kaspers, G. J.L., Van Der Schoot, C. E., Veerman, A. J.P., Van Dongen, J. J.M.
Publikováno v:
Pieters, R, Pongers-Willemse, M J, Den Boer, M L, Kaspers, G J L, Van Der Schoot, C E, Veerman, A J P & Van Dongen, J J M 1999, ' Chemotherapieresistentie en 'minimal residual disease' : Nieuwe mogelijkheden voor therapie op maat voor kinderen met leukemie? ', Tijdschrift voor Kindergeneeskunde, vol. 67, no. 5, pp. 209-213 .
Seventy-five % of children with acute lymphoblastic leukemia (ALL) are cured. The classical risk factors do not predict accurately which children will be cured and who will not. Recently two new methods have been developed that might be helpful to do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10172::7eefe3a5e71eb23bf89714b4586620b7
https://research.vumc.nl/en/publications/7e348a07-f25d-43c6-926f-4a842d77dd54
https://research.vumc.nl/en/publications/7e348a07-f25d-43c6-926f-4a842d77dd54
Autor:
Haarman, E. G., Kaspers, G. J.L., Pieters, R., Van Zantwijk, C. H., Broekema, G. J., Hählen, K., Veerman, A. J.P.
Publikováno v:
Advances in experimental medicine and biology, 457, 325-333. Springer New York
Advances in Experimental Medicine and Biology, 457, 325-333. Springer New York
Haarman, E G, Kaspers, G J L, Pieters, R, Van Zantwijk, C H, Broekema, G J, Hählen, K & Veerman, A J P 1999, ' Bcl-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance ', Advances in Experimental Medicine and Biology, vol. 457, pp. 325-333 . https://doi.org/10.1007/978-1-4615-4811-9_35
Advances in Experimental Medicine and Biology, 457, 325-333. Springer New York
Haarman, E G, Kaspers, G J L, Pieters, R, Van Zantwijk, C H, Broekema, G J, Hählen, K & Veerman, A J P 1999, ' Bcl-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance ', Advances in Experimental Medicine and Biology, vol. 457, pp. 325-333 . https://doi.org/10.1007/978-1-4615-4811-9_35
The antileukemic activity of cytotoxic drugs is increasingly thought to be the result of induction of apoptosis. Several proto-oncogenes have been related to the regulation of this process. In this study we evaluated the relation between bcl-2 expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7ad2bde8eb04fe43401d66fed5645b37
https://pure.eur.nl/en/publications/e1e3b42a-958d-44cb-abe0-440cb885a88a
https://pure.eur.nl/en/publications/e1e3b42a-958d-44cb-abe0-440cb885a88a