Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kasper Recourt"'
Autor:
Marije E. Otto, Kirsten R. Bergmann, Marieke L. deKam, Kasper Recourt, Gabriël E. Jacobs, Michiel J. vanEsdonk
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1425-1436 (2023)
Abstract In clinical trials, Montgomery‐Åsberg Depression Rating Scale (MADRS) questionnaire data are added up to total scores before analysis, assuming equal contribution of each separate question. Item Response Theory (IRT)‐based analysis avoi
Externí odkaz:
https://doaj.org/article/b368b3900d9748bb820769f968d0f7b2
Autor:
Kasper Recourt, Peter de Boer, Peter van der Ark, Heike Benes, Joop M. A. van Gerven, Marc Ceusters, Luc van Nueten, Wayne C. Drevets, Anindya Bhatacharya, Michael Browning, Gabriel E. Jacobs
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral interleukin (IL)-1β release, and attenuated dexamphetamine-induce
Externí odkaz:
https://doaj.org/article/ce0f225410c64ac8b7a1ca0270900c52
Autor:
Oleksandr Sverdlov, Jelena Curcic, Kristin Hannesdottir, Liangke Gou, Valeria De Luca, Francesco Ambrosetti, Bingsong Zhang, Jens Praestgaard, Vanessa Vallejo, Andrew Dolman, Baltazar Gomez-Mancilla, Konstantinos Biliouris, Mark Deurinck, Francesca Cormack, John J. Anderson, Nicholas T. Bott, Ziv Peremen, Gil Issachar, Offir Laufer, Dale Joachim, Raj R. Jagesar, Niels Jongs, Martien J. Kas, Ahnjili Zhuparris, Rob Zuiker, Kasper Recourt, Zoë Zuilhof, Jang-Ho Cha, Gabriel E. Jacobs
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Background: Digital technologies have the potential to provide objective and precise tools to detect depression-related symptoms. Deployment of digital technologies in clinical research can enable collection of large volumes of clinically relevant da
Externí odkaz:
https://doaj.org/article/72fd564b566f4cc386cf603a160ea3ee
Publikováno v:
Genes; Volume 13; Issue 8; Pages: 1407
Family health history (FHH) is a data type serving risk assessment, diagnosis, research, and preventive health. Despite technological leaps in genomic variant detection, FHH remains the most accessible, least expensive, and most practical assessment
Autor:
Margot M. Rakers, Hine J.A. van Os, Kasper Recourt, Georgio Mosis, Niels H Chavannes, Jeroen N. Struijs
Publikováno v:
Health Policy and Technology, 12(1). ELSEVIER SCI LTD
Objective: Structural reimbursement can be an important factor for large-scale implementing and upscaling of remote patient monitoring (RPM). During the COVID-19 pandemic, the Dutch Healthcare Authority expanded regulations, creating novel opportunit
Autor:
Gabriel E. Jacobs, Joop M. A. van Gerven, Pieter Siebenga, Marieke de Kam, Kawita M. S. Kanhai, Wayne C. Drevets, Paulien Ravenstijn, Luc Van Nueten, Maarten Timmers, Kasper Recourt, Rob Zuiker, Peter de Boer, Jasper van der Aart
Publikováno v:
Journal of Psychopharmacology, 34(9), 1030-1042. SAGE PUBLICATIONS LTD
Background: This is the first report of the pharmacodynamic (PD) effects of the selective, potent and brain-penetrant P2X7 receptor (P2X7R) antagonist JNJ-54175446. Activation of the P2X7R, an adenosine triphosphate-gated ion channel, leads to the pr
Autor:
Kasper Recourt, Peter de Boer, Rob Zuiker, Remy Luthringer, Justine Kent, Peter van der Ark, Ilse Van Hove, Joop van Gerven, Gabriel Jacobs, Luc van Nueten, Wayne Drevets
Publikováno v:
Translational Psychiatry. 9
In the original Article, Tables two and three had formatting issues which affected their clarity. This has been corrected in the PDF and HTML versions of this Article.
Autor:
Kasper Recourt, Wayne C. Drevets, Joop M. A. van Gerven, Luc Van Nueten, Peter van der Ark, Peter de Boer, Remy Luthringer, Justine M. Kent, Gabriel E. Jacobs, Ilse Van Hove, Rob Zuiker
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Translational Psychiatry
Translational Psychiatry, 9. NATURE PUBLISHING GROUP
Translational Psychiatry
Translational Psychiatry, 9. NATURE PUBLISHING GROUP
Excessive arousal has a role in the pathophysiology of major depressive disorder (MDD). Seltorexant (JNJ-42847922/MIN-202) is a selective antagonist of the human orexin-2 receptor (OX2R) that may normalize excessive arousal and thereby attenuate depr
Autor:
P. Van der Ark, Gabriel E. Jacobs, Rob Zuiker, Kasper Recourt, G. Van Amerongen, Remy Luthringer, J.M.A. van Gerven
Publikováno v:
European Neuropsychopharmacology, 27, S866-S866
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5bfe8cf7e7e1603bf47483a8905778
https://hdl.handle.net/1887/116418
https://hdl.handle.net/1887/116418