Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kasper KJ"'
Autor:
Mette Harboe, Kasper Kjaer-Sorensen, Ernst-Martin Füchtbauer, Robert A. Fenton, Jesper Skovhus Thomsen, Annemarie Brüel, Claus Oxvig
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Insulin-like growth factor (IGF) signaling is required for proper growth and skeletal development in vertebrates. Consequently, its dysregulation may lead to abnormalities of growth or skeletal structures. IGF is involved in the regulation o
Externí odkaz:
https://doaj.org/article/45aba06494fa43148864fd55ae942a88
Autor:
Mari Palviainen, Johanna Puutio, Rikke Halse Østergaard, Johannes A. Eble, Katariina Maaninka, Umar Butt, Joseph Ndika, Otto K. Kari, Masood Kamali‐Moghaddam, Kasper Kjaer‐Sorensen, Claus Oxvig, Ana M. Aransay, Juan M. Falcon‐Perez, Antonio Federico, Dario Greco, Saara Laitinen, Yuya Hayashi, Pia R.‐M. Siljander
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Renowned for their role in haemostasis and thrombosis, platelets are also increasingly recognized for their contribution in innate immunity, immunothrombosis and inflammatory diseases. Platelets express a wide range of receptors, which allow
Externí odkaz:
https://doaj.org/article/d1bacf0104064fd49990f7e4e0293c8c
Autor:
Cagla Cömert, Kasper Kjær-Sørensen, Jakob Hansen, Jasper Carlsen, Jesper Just, Brandon F. Meaney, Elsebet Østergaard, Yonglun Luo, Claus Oxvig, Lisbeth Schmidt-Laursen, Johan Palmfeldt, Paula Fernandez-Guerra, Peter Bross
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102009- (2024)
Objective: Mitochondrial proteostasis is critical for cellular function. The molecular chaperone HSP60 is essential for cell function and dysregulation of HSP60 expression has been implicated in cancer and diabetes. The few reported patients carrying
Externí odkaz:
https://doaj.org/article/3ec01ba56131408a8f12c0a8c06887b3
Autor:
Rasmus Hejlesen, Freja Burkarl Scheffler, Clara Garfiel Byrge, Kasper Kjær-Sørensen, Claus Oxvig, Angela Fago, Hans Malte
Publikováno v:
Biology Open, Vol 13, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/387e6ead3e1946319b7ce5f62ce86a91
Autor:
Anne Skakkebæk, Kasper Kjær-Sørensen, Vladimir V. Matchkov, Lise-Lotte Christensen, Jesper Just, Cagla Cömert, Niels Holmark Andersen, Claus Oxvig, Claus Højbjerg Gravholt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The genetic architecture of the QT interval, defined as the period from onset of depolarisation to completion of repolarisation of the ventricular myocardium, is incompletely understood. Only a minor part of the QT interval variation in the
Externí odkaz:
https://doaj.org/article/6353e4e709f04d6b8c35f814a8fad646
Autor:
Pernille Bogetofte Thomasen, Alena Salasova, Kasper Kjaer-Sorensen, Lucie Woloszczuková, Josef Lavický, Hande Login, Jeppe Tranberg-Jensen, Sergio Almeida, Sander Beel, Michaela Kavková, Per Qvist, Mads Kjolby, Peter Lund Ovesen, Stella Nolte, Benedicte Vestergaard, Andreea-Cornelia Udrea, Lene Niemann Nejsum, Moses V. Chao, Philip Van Damme, Jan Krivanek, Jeremy Dasen, Claus Oxvig, Anders Nykjaer
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113333- (2023)
Summary: Motor neuron (MN) development and nerve regeneration requires orchestrated action of a vast number of molecules. Here, we identify SorCS2 as a progranulin (PGRN) receptor that is required for MN diversification and axon outgrowth in zebrafis
Externí odkaz:
https://doaj.org/article/70f099b4a581474b967f6fa6ea663779
Autor:
Sara Nysom Christiansen, Felix Christoph Müller, Mikkel Østergaard, Ole Slot, Jakob M. Møller, Henrik F. Børgesen, Kasper Kjærulf Gosvig, Lene Terslev
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background Dual-energy CT (DECT) can acknowledge differences in tissue compositions and can colour-code tissues with specific features including monosodium urate (MSU) crystals. However, when evaluating gout patients, DECT frequently colour-
Externí odkaz:
https://doaj.org/article/97cbb971c1c24697810179ab910800e0
Autor:
Maximiliano José Nigro, Hinako Kirikae, Kasper Kjelsberg, Rajeevkumar Raveendran Nair, Menno P. Witter
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
The wide diversity of cortical inhibitory neuron types populating the cortex allows the assembly of diverse microcircuits and endows these circuits with different computational properties. Thus, characterizing neuronal diversity is fundamental to des
Externí odkaz:
https://doaj.org/article/0a43790aedc94f309496a7d6e920de30
Autor:
Chengdong Liu, Shuang Li, Pernille Rimmer Noer, Kasper Kjaer-Sorensen, Anna Karina Juhl, Allison Goldstein, Caihuan Ke, Claus Oxvig, Cunming Duan
Publikováno v:
eLife, Vol 9 (2020)
Human patients carrying PAPP‐A2 inactivating mutations have low bone mineral density. The underlying mechanisms for this reduced calcification are poorly understood. Using a zebrafish model, we report that Papp-aa regulates bone calcification by pr
Externí odkaz:
https://doaj.org/article/0bcae0e54105480c85a3d4cb42e66262
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Autor:
Kasper Thorsen, Vibeke S. Dam, Kasper Kjaer-Sorensen, Lisbeth N. Pedersen, V. Arvydas Skeberdis, Jonas Jurevičius, Rimantas Treinys, Ida M. B. S. Petersen, Morten S. Nielsen, Claus Oxvig, J. Preben Morth, Vladimir V. Matchkov, Christian Aalkjær, Henning Bundgaard, Henrik K. Jensen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Mutations in potassium and calcium channel genes have been associated with cardiac arrhythmias. Here, Jensen et al. show that an anion transporter chloride-bicarbonate exchanger AE3 is also responsible for the genetically-induced mechanism of cardiac
Externí odkaz:
https://doaj.org/article/97e6cbf2131e4127b04d04f0aede118d