Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production.

Autor: Tuffs SW; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Goncheva MI; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Xu SX; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Craig HC; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Kasper KJ; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Choi J; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Flannagan RS; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Kerfoot SM; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., Heinrichs DE; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada., McCormick JK; Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada; john.mccormick@uwo.ca.; Lawson Health Research Institute, London, ON N6A 4V2, Canada.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Feb 22; Vol. 119 (8).

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes.

Autor: Brouwer S; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., Barnett TC; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Nedlands, WA, Australia., Ly D; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia., Kasper KJ; Department of Microbiology and Immunology and the Centre for Human Immunology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada., De Oliveira DMP; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., Rivera-Hernandez T; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., Cork AJ; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., McIntyre L; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia., Jespersen MG; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia., Richter J; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., Schulz BL; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia., Dougan G; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Nizet V; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Yuen KY; State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Hong Kong, China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, Hong Kong, China., You Y; State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, 102206, China., McCormick JK; Department of Microbiology and Immunology and the Centre for Human Immunology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.; Lawson Health Research Institute, London, ON, Canada., Sanderson-Smith ML; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.; Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia., Davies MR; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.; Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia., Walker MJ; Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia. mark.walker@uq.edu.au.

Publikováno v: Nature communications [Nat Commun] 2020 Oct 06; Vol. 11 (1), pp. 5018. Date of Electronic Publication: 2020 Oct 06.

A controlled-release oral opioid supports S. aureus survival in injection drug preparation equipment and may increase bacteremia and endocarditis risk.

Autor: Kasper KJ; Department of Microbiology and Immunology, Western University, London, Canada., Manoharan I; Department of Medicine, Western University, London, Canada., Hallam B; Department of Epidemiology and Biostatistics, Western University, London, Canada., Coleman CE; Department of Microbiology and Immunology, Western University, London, Canada., Koivu SL; Department of Family Medicine, Western University, London, Canada., Weir MA; Department of Medicine, Western University, London, Canada.; Lawson Health Research Institute, London, Canada., McCormick JK; Department of Microbiology and Immunology, Western University, London, Canada.; Lawson Health Research Institute, London, Canada., Silverman MS; Department of Microbiology and Immunology, Western University, London, Canada.; Department of Medicine, Western University, London, Canada.; Lawson Health Research Institute, London, Canada.; Division of Infectious Diseases, Western University, London, Canada.

Publikováno v: PloS one [PLoS One] 2019 Aug 09; Vol. 14 (8), pp. e0219777. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).

A study protocol to characterise pathophysiological and molecular markers of rheumatic heart disease and degenerative aortic stenosis using multiparametric cardiovascular imaging and multiomics techniques.

Autor: Mutithu, Daniel W.^1,2,3 (AUTHOR), Aremu, Olukayode O.^1,2,3 (AUTHOR), Mokaila, Dipolelo^1,2,3 (AUTHOR), Bana, Tasnim^1,2,3 (AUTHOR), Familusi, Mary^2,4 (AUTHOR), Taylor, Laura⁵ (AUTHOR), Martin, Lorna J.⁵ (AUTHOR), Heathfield, Laura J.⁵ (AUTHOR), Kirwan, Jennifer A.^6,7 (AUTHOR), Wiesner, Lubbe⁸ (AUTHOR), Adeola, Henry A.⁹ (AUTHOR), Lumngwena, Evelyn N.^1,2,3,10 (AUTHOR), Manganyi, Rodgers¹¹ (AUTHOR), Skatulla, Sebastian⁴ (AUTHOR), Naidoo, Richard¹² (AUTHOR), Ntusi, Ntobeko A. B.^1,2,3,13,14 (AUTHOR) ntobeko.ntusi@uct.ac.za

Publikováno v: PLoS ONE. 5/13/2024, Vol. 19 Issue 5, p1-19. 19p.

Pathogenic potential of biofilm-producing methicillin-resistant Staphylococcus aureus in BALB/c mice.

Autor: Sannat, Chandrahas¹ csannat@rediffmail.com, Hirpurkar, S. D.¹, Shakya, Sanjay¹, DK Jolhe, Nidhi Rawat¹, Singh, Jasmeet¹, Jain, Tripti¹, Gumasta, Poornima¹, Patyal, Anil¹, Tripathi, S. M.¹, Kalim, M. O.¹, Barwa, Deepti Kiran¹, Deshmukh, Shivesh Kumar¹

Publikováno v: Indian Journal of Experimental Biology. Mar2024, Vol. 62 Issue 3, p206-213. 8p.