Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kaspars Megnis"'
Autor:
Ilze Elbere, Zigmunds Orlovskis, Laura Ansone, Ivars Silamikelis, Lauma Jagare, Liga Birzniece, Kaspars Megnis, Kristaps Leskovskis, Annija Vaska, Maris Turks, Kristaps Klavins, Valdis Pirags, Monta Briviba, Janis Klovins
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Metformin is widely used for treating type 2 diabetes mellitus (T2D). However, the efficacy of metformin monotherapy is highly variable within the human population. Understanding the potential indirect or synergistic effects of metformin on gut micro
Externí odkaz:
https://doaj.org/article/69e2187b22ff47c3be1527681e9d49fe
Autor:
Gundega Mūrniece, Žanete Šteingolde, Svetlana Cvetkova, Olga Valciņa, Ņikita Zrelovs, Monta Brīvība, Jānis Kloviņš, Līga Birzniece, Kaspars Megnis, Dāvids Fridmanis, Aivars Bērziņš, Līga Kovaļčuka, Kaspars Kovaļenko
Publikováno v:
Veterinary Medicine and Science, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Background The causative agent of the COVID‐19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is of zoonotic origin and has shown reverse zoonotic transmissibility. Objectives The aim of this cross‐sectional
Externí odkaz:
https://doaj.org/article/8a08b81eee69467482ee9db75aeb9a7f
Autor:
Rihards Saksis, Olesja Rogoza, Helvijs Niedra, Kaspars Megnis, Ilona Mandrika, Inga Balcere, Liva Steina, Janis Stukens, Austra Breiksa, Jurijs Nazarovs, Jelizaveta Sokolovska, Ilze Konrade, Raitis Peculis, Vita Rovite
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-21 (2023)
Abstract Pituitary neuroendocrine tumours (PitNETs) are neoplasms of the pituitary that overproduce hormones or cause unspecific symptoms due to mass effect. Growth hormone overproducing GH-producing PitNETs cause acromegaly leading to connective tis
Externí odkaz:
https://doaj.org/article/29d030e8136840839256602be7185efa
Autor:
Monta Brīvība, Laila Silamiķele, Līga Birzniece, Laura Ansone, Kaspars Megnis, Ivars Silamiķelis, Līva Pelcmane, Daniella Borisova, Maija Rozenberga, Lauma Jagare, Ilze Elbere, Jānis Kloviņš
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 567 (2024)
The gut microbiome plays a pivotal role in the modulation of host responses during viral infections, and recent studies have underscored its significance in the context of coronavirus disease 2019 (COVID-19). We aimed to investigate the dynamics and
Externí odkaz:
https://doaj.org/article/d4ba938c0bea4b7aa13950221fb8dd53
Autor:
Raimonds Reščenko, Monta Brīvība, Ivanna Atava, Vita Rovīte, Raitis Pečulis, Ivars Silamiķelis, Laura Ansone, Kaspars Megnis, Līga Birzniece, Mārcis Leja, Liqin Xu, Xulian Shi, Yan Zhou, Andis Slaitas, Yong Hou, Jānis Kloviņš
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15345 (2023)
Despite rapid improvements in the accessibility of whole-genome sequencing (WGS), understanding the extent of human genetic variation is limited by the scarce availability of genome sequences from underrepresented populations. Developing the populati
Externí odkaz:
https://doaj.org/article/8727ea7186bc4196a580b9f948361cbe
Autor:
Helvijs Niedra, Raitis Peculis, Helena Daiga Litvina, Kaspars Megnis, Ilona Mandrika, Inga Balcere, Mihails Romanovs, Liva Steina, Janis Stukens, Austra Breiksa, Jurijs Nazarovs, Jelizaveta Sokolovska, Rasa Liutkeviciene, Alvita Vilkevicute, Ilze Konrade, Vita Rovite
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCirculating plasma miRNAs have been increasingly studied in the field of pituitary neuroendocrine tumor (PitNET) research. Our aim was to discover circulating plasma miRNAs species associated with growth hormone (GH) secreting PitNETs versu
Externí odkaz:
https://doaj.org/article/d0a09e78ef7a42a8bbe8b9ca8021d4a0
Autor:
Mārtiņš Kalniņš, Andrejs Bērziņš, Dita Gudrā, Kaspars Megnis, Dāvids Fridmanis, Pavel Danilko, Olga Muter
Publikováno v:
AIMS Microbiology, Vol 6, Iss 1, Pp 32-42 (2020)
Removal of nitrogen from wastewaters (WW) represents a global problem. The low nitrification rate during WW treatment is often caused by ecotoxicity. This problem is attributed mostly to the industrial WW. Our study was focused on the testing of indu
Externí odkaz:
https://doaj.org/article/99c7bbe5f4f04790805448cb4048e523
Autor:
Raitis Peculis, Inga Balcere, Ilze Radovica-Spalvina, Ilze Konrade, Olivija Caune, Kaspars Megnis, Vita Rovite, Janis Stukens, Jurijs Nazarovs, Austra Breiksa, Aigars Kiecis, Ivars Silamikelis, Valdis Pirags, Janis Klovins
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient
Externí odkaz:
https://doaj.org/article/a485ff182a0d4727a020d9728d3a40bf
Autor:
Raitis Peculis, Vita Rovite, Kaspars Megnis, Inga Balcere, Austra Breiksa, Jurijs Nazarovs, Janis Stukens, Ilze Konrade, Jelizaveta Sokolovska, Valdis Pirags, Janis Klovins
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0265306 (2022)
Somatic genetic alterations in pituitary neuroendocrine tumors (PitNET) tissues have been identified in several studies, but detection of overlapping somatic PitNET candidate genes is rare. We sequenced and by employing multiple data analysis methods
Externí odkaz:
https://doaj.org/article/04201e00898143a6b737be3ce38337a0
Autor:
Nikita Zrelovs, Monta Ustinova, Ivars Silamikelis, Liga Birzniece, Kaspars Megnis, Vita Rovite, Lauma Freimane, Laila Silamikele, Laura Ansone, Janis Pjalkovskis, Davids Fridmanis, Baiba Vilne, Marta Priedite, Anastasija Caica, Mikus Gavars, Dmitry Perminov, Jelena Storozenko, Oksana Savicka, Elina Dimina, Uga Dumpis, Janis Klovins
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Remaining a major healthcare concern with nearly 29 million confirmed cases worldwide at the time of writing, novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 920 thousand deaths since its outbreak in China, Dec
Externí odkaz:
https://doaj.org/article/6fe67190413c4e4ca3599dfc8117311b