Zobrazeno 1 - 10
of 3 429
pro vyhledávání: '"Kaspars"'
Autor:
Ilva Liekniņa, Lasse Reimer, Teodors Panteļejevs, Alons Lends, Kristaps Jaudzems, Aadil El-Turabi, Hjalte Gram, Anissa Hammi, Poul Henning Jensen, Kaspars Tārs
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Alpha-synuclein (α-syn) inclusions in the brain are hallmarks of so-called Lewy body diseases. Lewy bodies contain mainly aggregated α-syn together with some other proteins. Monomeric α-syn lacks a well-defined three-dimensional structure
Externí odkaz:
https://doaj.org/article/6a9c552985514f57acc76478b018144c
Autor:
Aivaras Vaškevičius, Denis Baronas, Janis Leitans, Agnė Kvietkauskaitė, Audronė Rukšėnaitė, Elena Manakova, Zigmantas Toleikis, Algirdas Kaupinis, Andris Kazaks, Marius Gedgaudas, Aurelija Mickevičiūtė, Vaida Juozapaitienė, Helgi B Schiöth, Kristaps Jaudzems, Mindaugas Valius, Kaspars Tars, Saulius Gražulis, Franz-Josef Meyer-Almes, Jurgita Matulienė, Asta Zubrienė, Virginija Dudutienė, Daumantas Matulis
Publikováno v:
eLife, Vol 13 (2024)
We designed novel pre-drug compounds that transform into an active form that covalently modifies particular His residue in the active site, a difficult task to achieve, and applied to carbonic anhydrase (CAIX), a transmembrane protein, highly overexp
Externí odkaz:
https://doaj.org/article/d2000c0aa6154247b81fece6681bfd67
Autor:
Karina Goluba, Vadims Parfejevs, Evita Rostoka, Kaspars Jekabsons, Ilze Blake, Anastasija Neimane, Annija Anete Ule, Roberts Rimsa, Reinis Vangravs, Andrejs Pcolkins, Una Riekstina
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101262- (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer characterised by poor survival rates and an increasing global incidence. Advances in the staging and categorization of pancreatic tumours, along with the discovery of functional mu
Externí odkaz:
https://doaj.org/article/01a161a3e4874815bb09c01ca0e55f36
Autor:
Ilze Elbere, Zigmunds Orlovskis, Laura Ansone, Ivars Silamikelis, Lauma Jagare, Liga Birzniece, Kaspars Megnis, Kristaps Leskovskis, Annija Vaska, Maris Turks, Kristaps Klavins, Valdis Pirags, Monta Briviba, Janis Klovins
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Metformin is widely used for treating type 2 diabetes mellitus (T2D). However, the efficacy of metformin monotherapy is highly variable within the human population. Understanding the potential indirect or synergistic effects of metformin on gut micro
Externí odkaz:
https://doaj.org/article/69e2187b22ff47c3be1527681e9d49fe
Autor:
Vaida Paketurytė-Latvė, Alexey Smirnov, Elena Manakova, Lina Baranauskiene, Vytautas Petrauskas, Asta Zubrienė, Jurgita Matulienė, Virginija Dudutienė, Edita Čapkauskaitė, Audrius Zakšauskas, Janis Leitans, Saulius Gražulis, Kaspars Tars, Daumantas Matulis
Publikováno v:
IUCrJ, Vol 11, Iss 4, Pp 556-569 (2024)
Carbonic anhydrase (CA) was among the first proteins whose X-ray crystal structure was solved to atomic resolution. CA proteins have essentially the same fold and similar active centers that differ in only several amino acids. Primary sulfonamides ar
Externí odkaz:
https://doaj.org/article/ec3b8fbc0d5b437fa117aba7db414107
Autor:
Kevin G. Ruddick, Vittorio E. Brando, Alexandre Corizzi, Ana I. Dogliotti, David Doxaran, Clémence Goyens, Joel Kuusk, Quinten Vanhellemont, Dieter Vansteenwegen, Agnieszka Bialek, Pieter De Vis, Héloise Lavigne, Matthew Beck, Kenneth Flight, Anabel Gammaru, Luis González Vilas, Kaspars Laizans, Francesca Ortenzio, Pablo Perna, Estefania Piegari, Lucas Rubinstein, Morven Sinclair, Dimitry Van der Zande
Publikováno v:
Frontiers in Remote Sensing, Vol 5 (2024)
This paper describes a prototype network of automated in situ measurements of hyperspectral water reflectance suitable for satellite validation and water quality monitoring. Radiometric validation of satellite-derived water reflectance is essential t
Externí odkaz:
https://doaj.org/article/25c8bbf247ad41129a08dec4c5a7b93f
Autor:
Gundega Mūrniece, Žanete Šteingolde, Svetlana Cvetkova, Olga Valciņa, Ņikita Zrelovs, Monta Brīvība, Jānis Kloviņš, Līga Birzniece, Kaspars Megnis, Dāvids Fridmanis, Aivars Bērziņš, Līga Kovaļčuka, Kaspars Kovaļenko
Publikováno v:
Veterinary Medicine and Science, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Background The causative agent of the COVID‐19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is of zoonotic origin and has shown reverse zoonotic transmissibility. Objectives The aim of this cross‐sectional
Externí odkaz:
https://doaj.org/article/8a08b81eee69467482ee9db75aeb9a7f
Publikováno v:
Applied Sciences, Vol 14, Iss 21, p 10057 (2024)
In an era where buildings are increasingly becoming multifaceted entities, the paradigm of smart buildings has witnessed significant evolution. This advancement integrates sophisticated communication technologies, the Internet of Things (IoT), artifi
Externí odkaz:
https://doaj.org/article/77584d7ec24e473dafb8d83106afdf14
Autor:
Joel Kuusk, Alexandre Corizzi, David Doxaran, Kim Duong, Kenneth Flight, Joosep Kivastik, Kaspars Laizans, Edouard Leymarie, Silvar Muru, Christophe Penkerc’h, Kevin Ruddick
Publikováno v:
Frontiers in Remote Sensing, Vol 5 (2024)
Optical Earth observation satellites provide vast amounts of data on a daily basis. The top-of-atmosphere radiance measured by these satellites is usually converted to bottom-of-atmosphere radiance or reflectance which is then used for deriving numer
Externí odkaz:
https://doaj.org/article/57d999f01b0f42b5b4c4d35cb42cae55
Autor:
Andris Šutka, Anna Šutka, Henriks Dundurs, Blanca del Rosal, Mairis Iesalnieks, Kaspars Mālnieks, Artis Linarts, Anders J. Barlow, Ronald T. Leon, Amanda V. Ellis, Peter C. Sherrell
Publikováno v:
Advanced Energy & Sustainability Research, Vol 5, Iss 6, Pp n/a-n/a (2024)
Millions of tonnes of polystyrene (PS) are produced annually, with only an estimated 12% being recycled. Herein, the upcycling of expanded or foamed PS waste into electromechanically responsive triboelectric laminates (TLs) is described. These TLs po
Externí odkaz:
https://doaj.org/article/af48bf11e9b64c0dbeb7dbddca8750ea