Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kaspar van den Dries"'
Autor:
Kaspar van den Dries, Rut Besseling, Michiel Damen, Thanh N. Tran, Ad Gerich, Thanh T. Nguyen, Wim Oostra
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 114:471-481
Dry powder mixing is a wide spread Unit Operation in the Pharmaceutical industry. With the advent of in-line Near Infrared (NIR) Spectroscopy and Quality by Design principles, application of Process Analytical Technology to monitor Blend Uniformity (
Autor:
Herman Vromans, Kaspar van den Dries
Publikováno v:
Powder Technology. 189:165-171
Previous work of the authors [K. van den Dries, H. Vromans, Qualitative proof of liquid penetration-involved nucleation in a high shear mixer, Eur. J. Pharm. Sci. 58 (2004), 551–559.] revealed that the granule formation in a high shear mixer depend
Autor:
Kaspar van den Dries, Herman Vromans
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 58:551-559
The origination of granules in the early seconds is an important aspect of high shear granulation. To elucidate these mechanisms, a substandard amount (1.5% w/w) of an aqueous hydroxypropyl cellulose solution was added to four different lactose mixtu
Publikováno v:
Powder Technology. 133:228-236
Wet granulation is a process intended for size enlargement. A logical consequence is that many studies are focused on granule growth. However, next to built-up of granules granule breakage also occurs. The aim of this study is to investigate the wet
Autor:
Herman Vromans, Kaspar van den Dries
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 20(4-5)
Wet granulation of a powder mixture often leads to accumulation of the smallest particles in the large granules. The preferential uptake of these particles results in an inhomogeneous granulate. The aim of this study was to investigate the mechanism