Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors.

Autor: Kode J; Anti-Cancer Drug Screening Facility (ACDSF), Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India; Tumor Immunology & Immunotherapy Group, Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India; Homi Bhabha National Institute (HBNI), Training School Complex, Anushakti Nagar, Mumbai 400085, India. Electronic address: jkode@actrec.gov.in., Kovvuri J; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India; Department of Humanities and Sciences, Vardhaman College of Engineering (Autonomous), Shamshabad, Hyderabad, Telangana 501218, India. Electronic address: jeshmaphd2013@gmail.com., Nagaraju B; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India. Electronic address: nagarajuburri999@gmail.com., Jadhav S; Anti-Cancer Drug Screening Facility (ACDSF), Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: shaileshvjadhav55@gmail.com., Barkume M; Anti-Cancer Drug Screening Facility (ACDSF), Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: madan_barkume@yahoo.co.in., Sen S; Anti-Cancer Drug Screening Facility (ACDSF), Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: subratasen23.ss@gmail.com., Kasinathan NK; Anti-Cancer Drug Screening Facility (ACDSF), Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: kasinathan.nirmalkumar@gmail.com., Chaudhari P; Homi Bhabha National Institute (HBNI), Training School Complex, Anushakti Nagar, Mumbai 400085, India; Small Animal Imaging Facility, Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: pchaudhari@actrec.gov.in., Mohanty BS; Small Animal Imaging Facility, Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: bhabani.bmohanty@gmail.com., Gour J; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500 037, India. Electronic address: jeetugour1810@gmail.com., Sigalapalli DK; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500 037, India. Electronic address: dileepsigalapalli@gmail.com., Ganesh Kumar C; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India. Electronic address: cgkumar5@gmail.com., Pradhan T; Tumor Immunology & Immunotherapy Group, Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India. Electronic address: truptininadpradhan@gmail.com., Banerjee M; Homi Bhabha National Institute (HBNI), Training School Complex, Anushakti Nagar, Mumbai 400085, India; Molecular Biology Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India. Electronic address: manishab@barc.gov.in., Kamal A; Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500 037, India; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India. Electronic address: ahmedkamal@iict.res.in.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104447. Date of Electronic Publication: 2020 Nov 01.

Differential cytotoxic activity of Quercetin on colonic cancer cells depends on ROS generation through COX-2 expression.

Autor: Raja SB; Department of Biochemistry, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India. Electronic address: bharusha@gmail.com., Rajendiran V; Department of Biochemistry, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India., Kasinathan NK; Department of Biochemistry, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India., P A; Department of Biochemistry, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India., Venkatabalasubramanian S; Cardiomyocyte Toxicity and Oncology Research Lab, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA University, Thanjavur, 613401, Tamilnadu, India., Murali MR; Tissue Engineering Group, Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia., Devaraj H; Department of Zoology, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India., Devaraj SN; Department of Biochemistry, School of Life Sciences, Guindy Campus, University of Madras, Chennai, 600025, Tamilnadu, India. Electronic address: niranjali@yahoo.com.

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2017 Aug; Vol. 106 (Pt A), pp. 92-106. Date of Electronic Publication: 2017 May 04.