Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kasia Kieltyka"'
Autor:
Eric P. Gillis, Kyle Parcella, Michael Bowsher, James H. Cook, Christiana Iwuagwu, B. Narasimhulu Naidu, Manoj Patel, Kevin Peese, Haichang Huang, Lourdes Valera, Chunfu Wang, Kasia Kieltyka, Dawn D. Parker, Jean Simmermacher, Eric Arnoult, Robert T. Nolte, Liping Wang, John A. Bender, David B. Frennesson, Mark Saulnier, Alan Xiangdong Wang, Nicholas A. Meanwell, Makonen Belema, Umesh Hanumegowda, Susan Jenkins, Mark Krystal, John F. Kadow, Mark Cockett, Robert Fridell
Publikováno v:
Journal of Medicinal Chemistry. 66:1941-1954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec60862845d7a9e3c5ea18ee8c48c091
https://doi.org/10.1021/acs.jmedchem.2c01732
https://doi.org/10.1021/acs.jmedchem.2c01732
Autor:
Jeremy Stewart, John J. Herbst, Jun Zhang, Wilson Z. Shou, Marianne Vath, Harold N. Weller, Larry Elvebak, Kasia Kieltyka, Jennifer W. Maloney
Publikováno v:
Rapid Communications in Mass Spectrometry. 24:3593-3601
Quantification of small molecules using liquid chromatography/tandem mass spectrometry (LC/MS/MS) on a triple quadrupole mass spectrometer has become a common practice in bioanalytical support of in vitro adsorption, distribution, metabolism and excr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::705faa740a9babede8b2d0fdf318c833
https://doi.org/10.1002/rcm.4817
https://doi.org/10.1002/rcm.4817
Autor:
Wilson Z. Shou, Kasia Kieltyka, Christopher Cianci, Brian McAuliffe, Jun Zhang, Dieter M. Drexler
Publikováno v:
Journal of pharmaceutical sciences. 105(3)
Membrane-based devices typically used for serum protein binding determination are not fully applicable to highly lipophilic compounds because of nonspecific binding to the device membrane. Ultracentrifugation, however, completely eliminates the issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ddd20cbcba131c530daf12985e0a4
https://pubmed.ncbi.nlm.nih.gov/26886323
https://pubmed.ncbi.nlm.nih.gov/26886323
Autor:
Chris Baglieri, Tatyana Zvyaga, Marianne Vath, Shu Li, Kasia Kieltyka, Cheryl Ferraro, Jun Zhang, Wilson Z. Shou, Harold N. Weller, Dieter M. Drexler
Publikováno v:
Rapid communications in mass spectrometry : RCM. 23(11)
Liquid chromatography/tandem mass spectrometry (LC/MS/MS) is the bioanalytical method of choice to support plate-based, in vitro early ADME (Absorption, Distribution, Metabolism and Excretion) screens such as metabolic stability (Metstab) assessment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882d10b6b6cd6db39ade57e530644f44
https://pubmed.ncbi.nlm.nih.gov/19399765
https://pubmed.ncbi.nlm.nih.gov/19399765