Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kasia Goleniewska"'
Autor:
Jacqueline-Yvonne Cephus, Matthew T. Stier, Hubaida Fuseini, Jeffrey A. Yung, Shinji Toki, Melissa H. Bloodworth, Weisong Zhou, Kasia Goleniewska, Jian Zhang, Sarah L. Garon, Robert G. Hamilton, Vasiliy V. Poloshukin, Kelli L. Boyd, R. Stokes Peebles, Jr., Dawn C. Newcomb
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2487-2499 (2017)
Sex hormones regulate many autoimmune and inflammatory diseases, including asthma. As adults, asthma prevalence is 2-fold greater in women compared to men. The number of group 2 innate lymphoid cells (ILC2) is increased in patients with asthma, and w
Externí odkaz:
https://doaj.org/article/87fabe7a1e54432baf5024d79aed6767
Autor:
Weisong Zhou, Dustin R Dowell, Matthew M Huckabee, Dawn C Newcomb, Madison G Boswell, Kasia Goleniewska, Matthew T Lotz, Shinji Toki, Huiyong Yin, Songyi Yao, Chandramohan Natarajan, Pingsheng Wu, Subramaniam Sriram, Richard M Breyer, Garret A Fitzgerald, R Stokes Peebles
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33518 (2012)
Prostaglandin I(2) (PGI(2)), a lipid mediator currently used in treatment of human disease, is a critical regulator of adaptive immune responses. Although PGI(2) signaling suppressed Th1 and Th2 immune responses, the role of PGI(2) in Th17 differenti
Externí odkaz:
https://doaj.org/article/d774297d24ed40ff8729d84c5dc26fd2
Autor:
Kelli L. Boyd, Kasia Goleniewska, Weisong Zhou, Shinji Toki, Dawn C. Newcomb, Pingsheng Wu, Hirohito Kita, R. Stokes Peebles, Jian Zhang, Allison E. Norlander
Publikováno v:
The Journal of Immunology. 205:1157-1166
The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens, such as Alternaria alternata, is not fully defined
Autor:
Dawn C. Newcomb, K. Nichole Maloney, Eric P. Skaar, Walter J. Chazin, Kelli L. Boyd, R. Stokes Peebles, Lauren D. Palmer, C. Noel Maxwell, Shinji Toki, A. Kasia Goleniewska
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 61:459-468
Calprotectin is a heterodimer of the proteins S100A8 and S100A9, and it is an abundant innate immune protein associated with inflammation. In humans, calprotectin transcription and protein abundance are associated with asthma and disease severity. Ho
Autor:
Weisong, Zhou, Jian, Zhang, Shinji, Toki, Kasia, Goleniewska, Allison E, Norlander, Dawn C, Newcomb, Pingsheng, Wu, Kelli L, Boyd, Hirohito, Kita, R Stokes, Peebles
Publikováno v:
J Immunol
The cyclooxygenase (COX) metabolic pathway regulates immune responses and inflammation. The effect of the COX pathway on innate pulmonary inflammation induced by protease-containing fungal allergens such as Alternaria alternata is not fully defined.
Autor:
Dawn C. Newcomb, Weisong Zhou, Shinji Toki, Jian Zhang, Kasia Goleniewska, Marc O. Johnson, Melissa H. Bloodworth, R. Stokes Peebles
Publikováno v:
The Journal of Immunology. 201:1936-1945
IL-33 has pleiotropic functions in immune responses and promotes the development of allergic diseases and asthma. IL-33 induces Th2 differentiation and enhances type 2 cytokine production by CD4+ T cells. However, the regulation of IL-33–driven typ
Autor:
Kasia Goleniewska, Dawn C. Newcomb, Pingsheng Wu, R. Stokes Peebles, Weisong Zhou, Shinji Toki, Daniel E. Dulek, Jacqueline Cephus, Mark Boothby, Robert D. Collins, Jian Zhang
Publikováno v:
The Journal of Immunology. 197:1577-1586
Allergic airway diseases are immune disorders associated with heightened type 2 immune responses and IL-5 and IL-13 production at the site of inflammation. We have previously reported that cyclooxygenase (COX) inhibition by indomethacin augmented all
Autor:
Dawn C. Newcomb, Kasia Goleniewska, Alex Banathy, Padmini Komalavilas, R. Stokes Peebles, Kelly L. Boyd, Joyce Cheung-Flynn
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:225-233
Severe bronchospasm refractory to β-agonists is a challenging aspect of asthma therapy, and novel therapeutics are needed. β-agonist-induced airway smooth muscle (ASM) relaxation is associated with increases in the phosphorylation of the small heat
Autor:
Weisong Zhou, Jian Zhang, Shinji Toki, Kasia Goleniewska, Allison E. Norlander, Dawn C. Newcomb, Kelli L. Boyd, Hirohito Kita, R. Stokes Peebles
Publikováno v:
The Journal of Immunology. 204:148.11-148.11
The cyclooxygenase (COX) metabolic pathway has regulatory functions in immune responses and inflammation. However, the effect of the COX pathway on innate airway inflammation induced by protease-containing allergens such as Alternaria alternata is no
Autor:
Stokes Peebles, Mark Rusznak, Kasia Goleniewska, Weisong Zhou, Shinji Toki, Marc Todd, Matthew T. Stier, Jian Zhang, Liddy Malone
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:AB2