Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kasi Viswanatharaju Ruddraraju"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 5, Pp 624-627 (2016)
The title compound, 9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-{[(2R,4S,5R)-4-methoxy-5-(methoxymethyl)tetrahydrofuran-2-yl]amino}-1H-purin-6(9H)-one, C17H25N5O7, crystallizes with two independent molecules (A and B) in the asym
Externí odkaz:
https://doaj.org/article/1f5c7a323af8497a8971336ed8dc34f8
Publikováno v:
Microorganisms, Vol 9, Iss 1, p 14 (2020)
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis (Mtb). According to the World Health Organization, an estimated 10 million people developed TB in 2018. The occurrence of drug-resistant TB demands therapeutic a
Externí odkaz:
https://doaj.org/article/d7f9708ea44d4a689578fae500fde1c9
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 7, Pp 741-743 (2015)
The asymmetric unit of the title compound, C14H24N2O5S, contains two independent molecules (A and B). In each molecule, the isothiazolidin-3-one ring adopts an envelope conformation with the methylene C atom as the flap. In the crystal, the A molecul
Externí odkaz:
https://doaj.org/article/94fdace3892048ed850b047bd0b2e4d7
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 4, Pp 336-338 (2015)
The title compound, C24H32N4O8S, (I), crystallizes as a zwitterion. The terminal amine N atom of the [(2-{2-[2-(2-ammonioethoxy)ethoxy]ethoxy}ethyl)carbamoyl] side chain is protonated, while the 1,2,5-thiadiazolidin-3-one 1,1-dioxide N atom is deprot
Externí odkaz:
https://doaj.org/article/ea114d6c607641d5962663726b259e7e
Autor:
Michael K. Wendt, Jinmin Miao, Hao Chen, Sarah Libring, Kasi Viswanatharaju Ruddraraju, Zhong Yin Zhang, Luis Solorio
Publikováno v:
Oncogene
Metastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current targeted therapies via engagement of several growth promoting pathways. SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60097f15bc988f92120a7baccdda890
http://europepmc.org/articles/PMC7714690
http://europepmc.org/articles/PMC7714690
Autor:
Congwei Niu, Kasi Viswanatharaju Ruddraraju, Erica Anne Baker, Devesh Aggarwal, Li Wu, Zhong Yin Zhang, Ruo-Yu Zhang
Publikováno v:
Journal of Medicinal Chemistry. 63:9212-9227
Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis (Mtb). Mtb protein tyrosine phosphatase B (mPTPB) is a virulence factor required for Mtb survival in host macrophages. Consequently, mPTPB represents an exciting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85a87d9b5e25d596da3dfe7c2ed573e
https://doi.org/10.1021/acs.jmedchem.0c00302
https://doi.org/10.1021/acs.jmedchem.0c00302
Publikováno v:
Microorganisms, Vol 9, Iss 14, p 14 (2021)
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis (Mtb). According to the World Health Organization, an estimated 10 million people developed TB in 2018. The occurrence of drug-resistant TB demands therapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf41a7908fe8e3a6ea9dce45f3e999e
https://www.mdpi.com/2076-2607/9/1/14
https://www.mdpi.com/2076-2607/9/1/14
Publikováno v:
Mass Spectrometry-Based Chemical Proteomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181eb571d22e540a0e8ed998ebbd1190
https://doi.org/10.1002/9781118970195.ch4
https://doi.org/10.1002/9781118970195.ch4
Autor:
Kasi Viswanatharaju, Ruddraraju, Devesh, Aggarwal, Congwei, Niu, Erica Anne, Baker, Ruo-Yu, Zhang, Li, Wu, Zhong-Yin, Zhang
Publikováno v:
J Med Chem
Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis (Mtb). Mtb protein tyrosine phosphatase B (mPTPB) is a virulence factor required for Mtb survival in host macrophages. Consequently, mPTPB represents an exciting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0434cc56a1def20b5b55f4c50072fd97
https://pubmed.ncbi.nlm.nih.gov/32787087
https://pubmed.ncbi.nlm.nih.gov/32787087
Autor:
Adrian R. Laciak, David A. Korasick, Kent S. Gates, Min Luo, Michael T. Henzl, John J. Tanner, Jesse W. Wyatt, Kasi Viswanatharaju Ruddraraju
Publikováno v:
Biochemistry. 56:5910-5919
Aldehyde dehydrogenase 7A1 (ALDH7A1) catalyzes the terminal step of lysine catabolism, the NAD+-dependent oxidation of α-aminoadipate semialdehyde to α-aminoadipate. Structures of ALDH7A1 reveal the C-terminus is a gate that opens and closes in res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a32c2fb2032bf194d9b5ba46827961
https://doi.org/10.1021/acs.biochem.7b00803
https://doi.org/10.1021/acs.biochem.7b00803