Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems

Autor: Gunnar Schütz, Lars E. Olsson, Irvin Teh, Steven Sourbron, Andor Veltien, Jürgen E. Schneider, Michael Gottschalk, Iina Laitinen, William Lloyd, James P B O'Connor, Denise Steinmann, Hans Paul Juretschke, Catherine D. G. Hines, Sabina Ziemian, Xiaomeng Zhang, Simon Campbell, Sirisha Tadimalla, Claudia Green, Katja Hassemer, Kashmira Pindoria, John C. Waterton, Yanping Luo, Paul D. Hockings, Irma Mahmutovic Persson, Michael V. Haase, Klaus Strobel, Sascha Koehler

Publikováno v: Magnetic Resonance Imaging
Magnetic Resonance Imaging, 59, 121-129
Magnetic Resonance Imaging, 59, pp. 121-129
Waterton, J C, Hines, C D G, Hockings, P D, Laitinen, I, Ziemian, S, Campbell, S, Gottschalk, M, Green, C, Haase, M, Hassemer, K, Juretschke, H P, Koehler, S, Lloyd, W, Luo, Y, Mahmutovic Persson, I, O'Connor, J P B, Olsson, L E, Pindoria, K, Schneider, J E, Sourbron, S, Steinmann, D, Strobel, K, Tadimalla, S, Teh, I, Veltien, A, Zhang, X & Schütz, G 2019, ' Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems ', Magnetic Resonance Imaging, vol. 59, pp. 121-129 . https://doi.org/10.1016/j.mri.2019.03.008

Background: Many translational MR biomarkers derive from measurements of the water proton longitudinal relaxation rate R 1 , but evidence for between-site reproducibility of R 1 in small-animal MRI is lacking. Objective: To assess R 1 repeatability a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19081a1f799d0cd7ca9359bc97b8ba33
https://europepmc.org/articles/PMC6477178/

Effect of the TRPV1 antagonist SB-705498 on the nasal parasympathetic reflex response in the ovalbumin sensitized guinea pig

Autor: Giovanni Vitulli, Albert L. Busza, Laura Dinnewell, Simon P. Campbell, Kashmira Pindoria, Sally-Anne Thompson, Jane Denyer, Diane M. Coe, Marion Lines, Kumar Changani, Paula Saklatvala, Sarah Hotee, Keith Biggadike

Publikováno v: British Journal of Pharmacology. 169:580-589

Background and Purpose Nasal sensory nerves play an important role in symptoms associated with rhinitis triggered by environmental stimuli. Here, we propose that TRPV1 is pivotal in nasal sensory nerve activation and assess the potential of SB-705498

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d618a4f2cb412ee17abd06001a0a2456
https://doi.org/10.1111/bph.12145

Longitudinal characterization of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods

Autor: Simon Young, Katherine Elisabeth Wiley, Kumar Changani, Tony Nials, Steve Jordan, Michael V. Haase, Richard G. Knowles, Simon P. Campbell, Kashmira Pindoria, Mike Pedrick, S J Bolton, Robert Shaw, Catherine Pereira

Publikováno v: Clinical science (London, England : 1979). 125(12)

The present study investigated the role that imaging could have for assessing lung inflammation in a mouse model of HDM (house dust mite)-provoked allergic inflammation. Inflammation is usually assessed using terminal procedures such as BAL (bronchoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf17aaefd90a3ef8173635688c92ce48
https://pubmed.ncbi.nlm.nih.gov/23725401

Longitudinal characterisation of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods

Autor: Richard G. Knowles, Simon Young, Kumar Changani, Katherine Elisabeth Wiley, Catherine Pereira, S J Bolton, Steve Jordan, Kashmira Pindoria, Tony Nials, Robert Shaw, Simon P. Campbell, Mike Pedrick, Michael V. Haase

Publikováno v: Journal of Inflammation (London, England)

The present study investigated the role that imaging could have for assessing lung inflammation in a mouse model of a house dust mite (HDM) provoked allergic inflammation. Inflammation is usually assessed using terminal procedures such as bronchoalve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6086ecc9a2b8d7d9571e24a442b3779c
https://doi.org/10.1186/1476-9255-10-s1-p4

Effect of the TRPV1 antagonist SB-705498 on the nasal parasympathetic reflex response in the ovalbumin sensitized guinea pig.

Autor: Changani, Kumar¹, Hotee, Sarah², Campbell, Simon¹, Pindoria, Kashmira¹, Dinnewell, Laura², Saklatvala, Paula², Thompson, Sally ‐ Anne², Coe, Diane², Biggadike, Keith², Vitulli, Giovanni², Lines, Marion¹, Busza, Albert², Denyer, Jane²

Publikováno v: British Journal of Pharmacology. Jun2013, Vol. 169 Issue 3, p580-589. 10p. 2 Black and White Photographs, 8 Graphs.