Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kashi Javaherian"'
Autor:
Junko Yoshida, Robert T. Wicks, Andrea I. Zambrano, Betty M. Tyler, Kashi Javaherian, Rachel Grossman, Yassine J. Daoud, Peter Gehlbach, Henry Brem, Walter J. Stark
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
We assessed the antiangiogenic effects of subconjunctival injection of Fc-endostatin (FcE) using a human vascular endothelial growth factor-induced rabbit corneal neovascularization model. Angiogenesis was induced in rabbit corneas through intrastrom
Externí odkaz:
https://doaj.org/article/92dd39d85f344968bbe79b149433da1f
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 9, Pp 1849-1859 (2005)
Retention of lipoproteins to proteoglycans in the subendothelial matrix (SEM) is an early event in atherosclerosis. We recently reported that collagen XVIII and its proteolytically released fragment endostatin (ES) are differentially depleted in bloo
Externí odkaz:
https://doaj.org/article/d80d50c2ebbd4aafa96e628fb0bca127
Publikováno v:
Dose-Response, Vol 9 (2011)
Angiogenesis refers to growth of blood vessels from pre-existing ones. In 1971, Folkman proposed that by choking off the blood supply to tumors, they are starved, leading to their demise. A few years ago, the monoclonal antibody Avastin became the fi
Externí odkaz:
https://doaj.org/article/0258f5d27ab64e8da98b730a30d0523d
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9945 (2010)
Vascular endothelial growth factor VEGF(165) is a critical element for development of the vascular system in physiological and pathological angiogenesis. VEGF isoforms have different affinities for heparan sulphate proteoglycan (HSPG) as well as for
Externí odkaz:
https://doaj.org/article/b0935095bc2a4861adeea45ae52fec09
Autor:
Henry Brem, Yassine J. Daoud, Peter L. Gehlbach, Betty Tyler, Junko Yoshida, Rachel Grossman, Andrea I. Zambrano, Kashi Javaherian, Robert T. Wicks, Walter J. Stark
Publikováno v:
Journal of Ophthalmology
Journal of Ophthalmology, Vol 2015 (2015)
Journal of Ophthalmology, Vol 2015 (2015)
We assessed the antiangiogenic effects of subconjunctival injection of Fc-endostatin (FcE) using a human vascular endothelial growth factor-induced rabbit corneal neovascularization model. Angiogenesis was induced in rabbit corneas through intrastrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756dfdb1f885e0c29e9a750660fe9fda
https://doi.org/10.1155/2015/137136
https://doi.org/10.1155/2015/137136
Autor:
David Zurakowski, Kashi Javaherian, Susan M. Dallabrida, Judah Folkman, Amy E. Birsner, William T. Pu, Nesreen S. Ismail, Sadakatsu Ikeda, Matthew H. Kulke, Regina Sohn, Sarah B. Sunshine, Ellen M. Durand, Lauren Bazinet, Maria Rupnick
Publikováno v:
Proceedings of the National Academy of Sciences. 109:11306-11311
Antiangiogenesis therapy has become a vital part of the armamentarium against cancer. Hypertension is a dose-limiting toxicity for VEGF inhibitors. Thus, there is a pressing need to address the associated adverse events so these agents can be better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25adb2a14d6f55e9ec9d49eacb6622d0
https://doi.org/10.1073/pnas.1203275109
https://doi.org/10.1073/pnas.1203275109
Autor:
Henry Brem, Rachel Grossman, Bachchu Lal, Betty Tyler, Patti Zadnik, Lee Hwang, Kashi Javaherian
Publikováno v:
Journal of Neurosurgery. 115:1139-1146
Object Brain tumors pose many unique challenges to treatment. The authors hypothesized that Fc-endostatin may be beneficial. It is a newly synthesized recombinant human endostatin conjugated to the Fc domain of IgG with a long half-life (weeks) and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bacb42c6b0604c73064c026ad329845
https://doi.org/10.3171/2011.8.jns11125
https://doi.org/10.3171/2011.8.jns11125
Autor:
Amy E. Birsner, J. Samulski, Rodney K. Chan, J. Naspinski, Chengwen Li, David Zurakowski, K. M. Lo, Stephen D. Gillies, Judah Folkman, R. M. Tjin Tham Sjin, Kashi Javaherian
Publikováno v:
Cancer Gene Therapy. 13:619-627
Developing continuous systemic delivery of endostatin has been a goal of many laboratories. We have employed a method of gene therapy utilizing different viral constructs. Here, we report that a new serotype of adeno-associated viruses, which incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b1f1d5a6d9fcf8daa0254d7e3a4bf5
https://doi.org/10.1038/sj.cgt.7700938
https://doi.org/10.1038/sj.cgt.7700938
Autor:
David A. Sampson, Sarah Short, Kashi Javaherian, Robert J. D'Amato, Judah Folkman, Christian M. Becker
Publikováno v:
Fertility and Sterility. 85:71-77
Objective To determine the active peptide regions inside the angiogenesis inhibitor endostatin that can inhibit endothelial migration in vitro and also inhibit endometriosis in a mouse model. Design Pharmacologic intervention in a surgically induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc4b13a090f975689b0bc6808889673
https://doi.org/10.1016/j.fertnstert.2005.07.1290
https://doi.org/10.1016/j.fertnstert.2005.07.1290
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 9, Pp 1849-1859 (2005)
Retention of lipoproteins to proteoglycans in the subendothelial matrix (SEM) is an early event in atherosclerosis. We recently reported that collagen XVIII and its proteolytically released fragment endostatin (ES) are differentially depleted in bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b633b32be6d7a08d8b170128c013a5c1
https://doi.org/10.1194/jlr.m500241-jlr200
https://doi.org/10.1194/jlr.m500241-jlr200