Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kasey R. Skinner"'
Autor:
Hasibur Rehman, Darshan S. Chandrashekar, Chakravarthi Balabhadrapatruni, Saroj Nepal, Sai Akshaya Hodigere Balasubramanya, Abigail K. Shelton, Kasey R. Skinner, Ai-Hong Ma, Ting Rao, Sumit Agarwal, Marie-Lisa Eich, Alyncia D. Robinson, Gurudatta Naik, Upender Manne, George J. Netto, C. Ryan Miller, Chong-xian Pan, Guru Sonpavde, Sooryanarayana Varambally, James E. Ferguson III
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Metastatic urothelial carcinoma is generally incurable with current systemic therapies. Chromatin modifiers are frequently mutated in bladder cancer, with ARID1A-inactivating mutations present in about 20% of tumors. EZH2, a histone methyltransferase
Externí odkaz:
https://doaj.org/article/8e79799b8d1942819fca44a09858150e
Autor:
Benjamin Lin, Julia Ziebro, Erin Smithberger, Kasey R Skinner, Eva Zhao, Timothy F Cloughesy, Zev A Binder, Donald M O’Rourke, David A Nathanson, Frank B Furnari, C Ryan Miller
Publikováno v:
Neuro-Oncology. 24:2035-2062
The Lazarus effect is a rare condition that happens when someone seemingly dead shows signs of life. The epidermal growth factor receptor (EGFR) represents a target in the fatal neoplasm glioblastoma (GBM) that through a series of negative clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d634d625457df2a8f7f488d32e641c52
https://doi.org/10.1093/neuonc/noac204
https://doi.org/10.1093/neuonc/noac204
Autor:
Kasey R. Skinner, Tomoyuki Koga, Shunichiro Miki, Robert F. Gruener, Florina-Nicoleta Grigore, Emma H. Torii, Davis M. Seelig, Yuta Suzuki, Daisuke Kawauchi, Benjamin Lin, Denise M. Malicki, Clark C. Chen, Etty N. Benveniste, Rakesh P. Patel, Braden C. McFarland, R. Stephanie Huang, Chris Jones, Alan Mackay, C. Ryan Miller, Frank B. Furnari
Diffuse midline glioma (DMG) is a leading cause of brain tumor death in children. In addition to hallmark H3.3K27M mutations, significant subsets also harbor alterations of other genes, such asTP53andPDGFRA. Despite the prevalence of H3.3K27M, the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18e8f9817da251f804e4263e4f71115d
https://doi.org/10.1101/2023.02.24.528982
https://doi.org/10.1101/2023.02.24.528982
Autor:
Robert S McNeill, Emily E Stroobant, Erin Smithberger, Demitra A Canoutas, Madison K Butler, Abigail K Shelton, Shrey D Patel, Juanita C Limas, Kasey R Skinner, Ryan E Bash, Ralf S Schmid, C Ryan Miller
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200014 (2018)
BackgroundGlioblastoma (GBM) is the most common adult primary brain tumor. Multimodal treatment is empiric and prognosis remains poor. Recurrent PIK3CA missense mutations (PIK3CAmut) in GBM are restricted to three functional domains: adaptor binding
Externí odkaz:
https://doaj.org/article/92b83fbb89a04d94995e568571c0a718
Autor:
Benjamin Lin, Julia Ziebro, Erin Smithberger, Kasey R Skinner, Eva Zhao, Timothy F Cloughesy, Zev A Binder, Donald M O’Rourke, David A Nathanson, Frank B Furnari, C Ryan Miller
Publikováno v:
Neuro Oncol
The Lazarus effect is a rare condition that happens when someone seemingly dead shows signs of life. The epidermal growth factor receptor (EGFR) represents a target in the fatal neoplasm glioblastoma (GBM) that through a series of negative clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d03a3f524fe54f270aa922ea522312
https://europepmc.org/articles/PMC9825333/
https://europepmc.org/articles/PMC9825333/
Autor:
Shunichiro Miki, Tomoyuki Koga, Kasey R Skinner, Robert F Gruener, Daisuke Kawauchi, R Stephanie Huang, C Ryan Miller, Frank Furnari
Publikováno v:
Neuro-Oncology Advances. 4:iii6-iii6
Histone H3 K27M mutation is a hallmark mutation for H3 K27M-mutant diffuse midline glioma (DMG), but targeting this mutation has yet to achieve a significant survival benefit in clinical trials. Recent analyses revealed alterations in several genes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c8d1cac641b156257e98aa852445dbc
https://doi.org/10.1093/noajnl/vdac167.020
https://doi.org/10.1093/noajnl/vdac167.020
Autor:
Hasibur Rehman, Darshan S. Chandrashekar, Chakravarthi Balabhadrapatruni, Saroj Nepal, Sai Akshaya Hodigere Balasubramanya, Abigail K. Shelton, Kasey R. Skinner, Ai-Hong Ma, Ting Rao, Sumit Agarwal, Marie-Lisa Eich, Alyncia D. Robinson, Gurudatta Naik, Upender Manne, George J. Netto, C. Ryan Miller, Chong-xian Pan, Guru Sonpavde, Sooryanarayana Varambally, James E. Ferguson
Publikováno v:
JCI insight. 7(16)
Metastatic urothelial carcinoma is generally incurable with current systemic therapies. Chromatin modifiers are frequently mutated in bladder cancer, with ARID1A-inactivating mutations present in about 20% of tumors. EZH2, a histone methyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27394b3b112dfff88d4d62c6ba59f5d9
https://pubmed.ncbi.nlm.nih.gov/35852858
https://pubmed.ncbi.nlm.nih.gov/35852858
Autor:
Benjamin Lin, Julia Ziebro, Kasey R. Skinner, Abigail Shelton, Erin Smithberger, Ryan Bash, Frank B. Furnari, Ryan Miller
Publikováno v:
Cancer Research. 82:1125-1125
Glioblastoma (GBM) is the most common malignant brain tumor in adults with a dismal 15-month median survival. Standard therapy consisting of surgical resection, radiation, and temozolomide has been unsuccessful in meaningfully extending survival and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88f9ad33b8bb9982fc9b68440f6e441
https://doi.org/10.1158/1538-7445.am2022-1125
https://doi.org/10.1158/1538-7445.am2022-1125
Autor:
Shunichiro Miki, R. Stephanie Huang, Denise M. Malicki, Frank B. Furnari, Sriram Venneti, Robert J. Wechsler-Reya, Tomoyuki Koga, Clark C. Chen, Robert F. Gruener, C. Ryan Miller, Kasey R Skinner
Publikováno v:
Neuro Oncol
Diffuse midline glioma is the leading cause of brain tumor death among the pediatric population. Drugs that show notable promise in preclinical models inevitably fail to demonstrate efficacy in clinical trials, likely due to the inadequacy of preclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56a8b8b74dc21cf406757e63fd0e1b9
https://europepmc.org/articles/PMC7651541/
https://europepmc.org/articles/PMC7651541/
Autor:
Thomas J. Meyer, Seth L. Marquard, Michael S. Eberhart, Kasey R. Skinner, Degao Wang, Kyung Ryang Wee, Animesh Nayak
Publikováno v:
ChemSusChem. 10:2380-2384
Here, the application of the fluorinated polymer [Dupont AF, a copolymer of 4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole and tetrafluoroethylene] is described in stabilizing phosphonate-derivatized molecular assemblies on oxide electrodes. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891a66e500d05bc4da8cc4b3b357d394
https://doi.org/10.1002/cssc.201700630
https://doi.org/10.1002/cssc.201700630