Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kasey C. Nelson"'
Autor:
Xianxing Du, Elsa K. Mak, Xing Xian Yu, David C. Pallas, Egon Ogris, Kasey C. Nelson, William S. Lane
Publikováno v:
Journal of Biological Chemistry. 274:14382-14391
Carboxymethylation of proteins is a highly conserved means of regulation in eukaryotic cells. The protein phosphatase 2A (PP2A) catalytic (C) subunit is reversibly methylated at its carboxyl terminus by specific methyltransferase and methylesterase e
Autor:
Kasey C, Nelson, Jeffrey S, Armstrong, Siobhan, Moriarty, Jiyang, Cai, Mei-Whey H, Wu, Paul, Sternberg, Dean P, Jones
Publikováno v:
Investigative ophthalmologyvisual science. 43(11)
To determine whether oltipraz (4-methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione) protects against oxidative injury in cultured human retinal pigment epithelial (hRPE) cells.Primary cultured hRPE cells were incubated with various concentrations of oltipr
Autor:
Shunai, Jiang, Siobhan E, Moriarty, Hans, Grossniklaus, Kasey C, Nelson, Dean P, Jones, Paul, Sternberg
Publikováno v:
Investigative ophthalmologyvisual science. 43(8)
To determine whether long-term cultured nondividing human retinal pigment epithelial (hRPE) cells are sensitive to oxidant-induced apoptosis and whether the Fas pathway is involved in the process.Confluent hRPE cells were maintained for 2 to 3 months
Autor:
Carlos S. Moreno, Danita G. Ashby, William S. Lane, Frantisek Hubalek, Kasey C. Nelson, David C. Pallas, Susan Park
Publikováno v:
The Journal of biological chemistry. 275(8)
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many cellular processes including development, neuronal signaling, cell cycle regulation, and viral transformation. PP2A has been implicated in Ca(2+)
Publikováno v:
Progress in retinal and eye research. 19(2)
This review provides a model for the role of oxidative stress in the etiology of age-related macular degeneration (AMD). Epidemiological studies of diet, environmental and behavioral risk factors suggest that oxidative stress is a contributing factor
Publikováno v:
Molecular and cellular neurosciences. 6(6)
In the mammalian forebrain most neurons originate from proliferating cells in the ventricular zone lining the lateral ventricles. These neurons become postmitotic before they undergo migration to their final destinations. In this study we examined th