Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kasen R. Hutchings"'
Autor:
Kevin J. Pridham, Kasen R. Hutchings, Patrick Beck, Min Liu, Eileen Xu, Erin Saechin, Vincent Bui, Chinkal Patel, Jamie Solis, Leah Huang, Allison Tegge, Deborah F. Kelly, Zhi Sheng
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109921- (2024)
Summary: Resistance to chemotherapies such as temozolomide is a major hurdle to effectively treat therapy-resistant glioblastoma. This challenge arises from the activation of phosphatidylinositol 3-kinase (PI3K), which makes it an appealing therapeut
Externí odkaz:
https://doaj.org/article/5a04dfc5957141aab0cc95b2f89bf3bb
Autor:
Kevin J. Pridham, Farah Shah, Kasen R. Hutchings, Kevin L. Sheng, Sujuan Guo, Min Liu, Pratik Kanabur, Samy Lamouille, Gabrielle Lewis, Marc Morales, Jane Jourdan, Christina L. Grek, Gautam G. Ghatnekar, Robin Varghese, Deborah F. Kelly, Robert G. Gourdie, Zhi Sheng
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-11 (2022)
Abstract Circumventing chemoresistance is crucial for effectively treating cancer including glioblastoma, a lethal brain cancer. The gap junction protein connexin 43 (Cx43) renders glioblastoma resistant to chemotherapy; however, targeting Cx43 is di
Externí odkaz:
https://doaj.org/article/f1ac0b6e646148b5b519e962c8c96c1b
Autor:
Kasen R. Hutchings, Seth J. Fritzhand, Bita Esmaeli, Kirthi Koka, Jiawei Zhao, Salmaan Ahmed, James Matthew Debnam
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 312 (2023)
Graves’ disease is an autoimmune disorder in which hyperthyroidism results in various systematic symptoms, with about 30% of patients presenting with Graves’ eye disease (GED). The majority of patients with GED develop mild symptoms, including ey
Externí odkaz:
https://doaj.org/article/50a9570bdbc94096b929bfb0d9a48f51
Publikováno v:
Cancer Research. 82:3243-3243
Glioblastoma is the most common central nervous system cancer and is responsible for approximately one-half of all malignant brain tumors. With a 5-year survival rate of 6.8% and a median observed survival time of only 8 months, recurrent glioblastom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8593ee1107cbddc051f9d2092ec89843
https://doi.org/10.1158/1538-7445.am2022-3243
https://doi.org/10.1158/1538-7445.am2022-3243