Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kasei Miura"'
Autor:
Takahiro Tanaka, Shiho Matsumoto-Okano, Nobuhiro Inatomi, Yasushi Fujioka, Hidenori Kamiguchi, Masashi Yamaguchi, Akio Imanishi, Makiko Kawamoto, Kasei Miura, Yoichi Nishikawa, Yasuhiro Tsukimi
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 4, Pp 487-495 (2012)
We attempted to establish and validate an in vivo pharmacodynamic (PD) rabbit model to screen tachykinin NK2 receptor (NK2-R) antagonists using pharmacological and pharmacokinetic (PK)/PD analyses. Under urethane anesthesia, changes in intracolonic p
Externí odkaz:
https://doaj.org/article/0806af0bcee4466e990863cb54999d4d
Autor:
Takahiro Tanaka, Akiko Tanaka, Akihiro Nakamura, Kozo Matsushita, Akio Imanishi, Shiho Matsumoto-Okano, Nobuhiro Inatomi, Kasei Miura, Masao Toyoda, Gaku Mizojiri, Yasuhiro Tsukimi
Publikováno v:
Journal of Pharmacological Sciences, Vol 120, Iss 1, Pp 15-25 (2012)
TAK-480, 4-(difluoromethoxy)-N-((1R,2S)-2-(((3aR,4R,9bR)-4-(methoxymethyl)-2, 3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinolin-1-yl)carbonyl)cyclohexyl)benzamide, is a novel tachykinin NK2–receptor antagonist. In this study, we investigated its anta
Externí odkaz:
https://doaj.org/article/7f7e33b0302a467eb8190607814504fa
Publikováno v:
Human Centred Intelligent Systems ISBN: 9789819934232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4b5193dfe8d24f3dcc3bd0bb9e7d73
https://doi.org/10.1007/978-981-99-3424-9_14
https://doi.org/10.1007/978-981-99-3424-9_14
Autor:
Tetsuro Miyake, Yoshimasa Masuda, Katsura Deguchi, Masashi Iwasaki, Kazuya Obanayama, Kasei Miura
Publikováno v:
Innovation in Medicine and Healthcare ISBN: 9789811934391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03326aabf400ae67ce6df10b2c2d444
https://doi.org/10.1007/978-981-19-3440-7_24
https://doi.org/10.1007/978-981-19-3440-7_24
Publikováno v:
2021 10th International Congress on Advanced Applied Informatics (IIAI-AAI).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b070be7b2ac854d567cef3972c8801a
https://doi.org/10.1109/iiai-aai53430.2021.00116
https://doi.org/10.1109/iiai-aai53430.2021.00116
Publikováno v:
Innovation in Medicine and Healthcare ISBN: 9789811630125
Manufacturers of pharmaceuticals and medical devices are accountable for the quality and stable supply of their health-related products. In order to guarantee the provision of products that meet quality requirements, they have established and are ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50ca651e8b6b68fbad24a5d3cf8df11
https://doi.org/10.1007/978-981-16-3013-2_11
https://doi.org/10.1007/978-981-16-3013-2_11
Autor:
Makiko Kawamoto, Yasuhiro Tsukimi, Takahiro Tanaka, Nishikawa Yoichi, Kasei Miura, Hidenori Kamiguchi, Nobuhiro Inatomi, Akio Imanishi, Masashi Yamaguchi, Shiho Matsumoto-Okano, Yasushi Fujioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 118, Iss 4, Pp 487-495 (2012)
We attempted to establish and validate an in vivo pharmacodynamic (PD) rabbit model to screen tachykinin NK2 receptor (NK2-R) antagonists using pharmacological and pharmacokinetic (PK)/PD analyses. Under urethane anesthesia, changes in intracolonic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb98591b31982ddc1e4fa444a1ef60dd
http://www.sciencedirect.com/science/article/pii/S1347861319305420
http://www.sciencedirect.com/science/article/pii/S1347861319305420
Publikováno v:
Helvetica Chimica Acta. 85:3130-3135
Intramolecular substitution reaction of geminal dibromo alkenes proceeds to afford indenes, dihydronaphthalenes, dihydrofurans, and dihydropyran via in situ generated lithium alkylidene carbenoids, which have a carbon or oxygen nucleophilic moiety. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ed4d25c124fec383791cc9cfde3f5e
https://doi.org/10.1002/1522-2675(200210)85:10<3130::aid-hlca3130>3.0.co
https://doi.org/10.1002/1522-2675(200210)85:10<3130::aid-hlca3130>3.0.co
Autor:
Kozo Matsushita, Masao Toyoda, Takahiro Tanaka, Yasuhiro Tsukimi, Kasei Miura, Nobuhiro Inatomi, Gaku Mizojiri, Akihiro Nakamura, Akio Imanishi, Akiko Tanaka, Shiho Matsumoto-Okano
Publikováno v:
Journal of Pharmacological Sciences, Vol 120, Iss 1, Pp 15-25 (2012)
TAK-480, 4-(difluoromethoxy)-N-((1R,2S)-2-(((3aR,4R,9bR)-4-(methoxymethyl)-2, 3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinolin-1-yl)carbonyl)cyclohexyl)benzamide, is a novel tachykinin NK2–receptor antagonist. In this study, we investigated its anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8319fe77d7247ea80d605f205fbd8c
https://pubmed.ncbi.nlm.nih.gov/22893394
https://pubmed.ncbi.nlm.nih.gov/22893394
Publikováno v:
Organic letters. 6(14)
[reaction: see text] The intramolecular in-plane S(N)2 type reaction of haloalkene E-8a was predicted to be a facile process for the first time by DFT calculations (B3LYP/6-31+G(d),SCRF(dipole, solvent = DMF)) (DeltaG = 14.4 kcal/mol). The prediction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8629241aaa69eab325dfa4bcf89b581
https://pubmed.ncbi.nlm.nih.gov/15228304
https://pubmed.ncbi.nlm.nih.gov/15228304