Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kas J, Houthuijs"'
Autor:
Peter H. Moons, Floor ter Braak, Frank F. J. de Kleijne, Bart Bijleveld, Sybren J. R. Corver, Kas J. Houthuijs, Hero R. Almizori, Giel Berden, Jonathan Martens, Jos Oomens, Paul B. White, Thomas J. Boltje
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Attaining complete anomeric control is still one of the biggest challenges in carbohydrate chemistry. Glycosyl cations such as oxocarbenium and dioxanium ions are key intermediates of glycosylation reactions. Characterizing these highly-reac
Externí odkaz:
https://doaj.org/article/03d3bba4f2e34c4c9342a546b695ae9d
Autor:
Lara van Tetering, Sylvia Spies, Quirine D. K. Wildeman, Kas J. Houthuijs, Rianne E. van Outersterp, Jonathan Martens, Ron A. Wevers, David S. Wishart, Giel Berden, Jos Oomens
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Modern untargeted mass spectrometry (MS) analyses quickly detect and resolve thousands of molecular compounds. Although features are readily annotated with a molecular formula in high-resolution small-molecule MS applications, the large majo
Externí odkaz:
https://doaj.org/article/eb2bf19b8e0e4cc8882aa455e8b499a1
Autor:
Thomas Hansen, Hidde Elferink, Jacob M. A. van Hengst, Kas J. Houthuijs, Wouter A. Remmerswaal, Alexandra Kromm, Giel Berden, Stefan van der Vorm, Anouk M. Rijs, Hermen S. Overkleeft, Dmitri V. Filippov, Floris P. J. T. Rutjes, Gijsbert A. van der Marel, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée, Thomas J. Boltje
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Dioxolenium ion intermediates formed from remote positions are hypothesized to direct stereoselective glycosylations. Herein we combine infrared ion spectroscopy, DFT calculations and synthetic work to characterize and study these dioxolenium ions an
Externí odkaz:
https://doaj.org/article/6ec49b5d3eff4a6ea8a8b5a70ecb1904
Autor:
Kas J. Houthuijs, Giel Berden, Udo F. H. Engelke, Vasuk Gautam, David S. Wishart, Ron A. Wevers, Jonathan Martens, Jos Oomens
Infrared ion spectroscopy (IRIS) continues to see increasing use as an analytical tool for small-molecule identification in conjunction with mass spectrometry (MS). The IR spectrum of an m/z selected population of ions constitutes a unique fingerprin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::627e5055eba44b16ede1f21170482234
https://doi.org/10.26434/chemrxiv-2023-5grq5
https://doi.org/10.26434/chemrxiv-2023-5grq5
Autor:
Floor ter Braak, Hidde Elferink, Kas J. Houthuijs, Jos Oomens, Jonathan Martens, Thomas J. Boltje
Publikováno v:
Accounts of Chemical Research, 55, 1669-1679
Accounts of Chemical Research, 55, 12, pp. 1669-1679
Accounts of Chemical Research, 55, 12, pp. 1669-1679
A detailed understanding of the reaction mechanism(s) leading to stereoselective product formation is crucial to understanding and predicting product formation and driving the development of new synthetic methodology. One way to improve our understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b97408121e3dc3678c34f5f9921136
https://doi.org/10.1021/acs.accounts.2c00040
https://doi.org/10.1021/acs.accounts.2c00040
Autor:
Jona Merx, Kas J. Houthuijs, Hidde Elferink, Eva Witlox, Jasmin Mecinović, Jos Oomens, Jonathan Martens, Thomas J. Boltje, Floris P. J. T. Rutjes
Publikováno v:
Chemistry : a European Journal, 28, 1-7
Chemistry : a European Journal, 28, 9, pp. 1-7
Merx, J, Houthuijs, K, Elferink, H, Witlox, E, Mecinović, J, Oomens, J, Martens, J, Boltje, T & Rutjes, F P J T 2022, ' Characterization of Cyclic N-Acyliminium Ions by Infrared Ion Spectroscopy ', Chemistry: A European Journal, vol. 28, no. 9, e202104078 . https://doi.org/10.1002/chem.202104078
Chemistry : a European Journal, 28, 9, pp. 1-7
Merx, J, Houthuijs, K, Elferink, H, Witlox, E, Mecinović, J, Oomens, J, Martens, J, Boltje, T & Rutjes, F P J T 2022, ' Characterization of Cyclic N-Acyliminium Ions by Infrared Ion Spectroscopy ', Chemistry: A European Journal, vol. 28, no. 9, e202104078 . https://doi.org/10.1002/chem.202104078
N- Acyliminium ions are highly reactive intermediates that are important for creating CC-bonds adjacent to nitrogen atoms. Here we report the characterization of cyclic N -acyliminium ions in the gas phase, generated by collision induced dissociation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59463d52ea7426e67928ea2fc1db5ccf
https://hdl.handle.net/2066/247915
https://hdl.handle.net/2066/247915
Autor:
Hidde Elferink, Wouter A. Remmerswaal, Kas J. Houthuijs, Oscar Jansen, Thomas Hansen, Anouk M. Rijs, Giel Berden, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée, Thomas J. Boltje
Publikováno v:
Chemistry-A European Journal, 28(63):e202201724, 1-8. Wiley-VCH Verlag
Chemistry: a European Journal, 28(63):e202201724
Chemistry: a European Journal, 28(63):e202201724. WILEY-V C H VERLAG GMBH
Chemistry : a European Journal, 28, 63, pp. 1-7
Elferink, H, Remmerswaal, W A, Houthuijs, K J, Jansen, O, Hansen, T, Rijs, A M, Berden, G, Martens, J, Oomens, J, Codée, J D C & Boltje, T J 2022, ' Competing C-4 and C-5-Acyl Stabilization of Uronic Acid Glycosyl Cations ', Chemistry-A European Journal, vol. 28, no. 63, e202201724, pp. 1-8 . https://doi.org/10.1002/chem.202201724
Chemistry : a European Journal, 28, 1-7
Chemistry: a European Journal, 28(63):e202201724
Chemistry: a European Journal, 28(63):e202201724. WILEY-V C H VERLAG GMBH
Chemistry : a European Journal, 28, 63, pp. 1-7
Elferink, H, Remmerswaal, W A, Houthuijs, K J, Jansen, O, Hansen, T, Rijs, A M, Berden, G, Martens, J, Oomens, J, Codée, J D C & Boltje, T J 2022, ' Competing C-4 and C-5-Acyl Stabilization of Uronic Acid Glycosyl Cations ', Chemistry-A European Journal, vol. 28, no. 63, e202201724, pp. 1-8 . https://doi.org/10.1002/chem.202201724
Chemistry : a European Journal, 28, 1-7
Uronic acids are carbohydrates carrying a terminal carboxylic acid and have a unique reactivity in stereoselective glycosylation reactions. Herein, the competing intramolecular stabilization of uronic acid cations by the C-5 carboxylic acid or the C-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13abe4d5caebc803f690299bb6b1cd1b
https://research.vu.nl/en/publications/7bbdd644-22fa-40f7-bb9c-8ace539559b9
https://research.vu.nl/en/publications/7bbdd644-22fa-40f7-bb9c-8ace539559b9
Autor:
Wouter A, Remmerswaal, Kas J, Houthuijs, Roel, van de Ven, Hidde, Elferink, Thomas, Hansen, Giel, Berden, Herman S, Overkleeft, Gijsbert A, van der Marel, Floris P J T, Rutjes, Dmitri V, Filippov, Thomas J, Boltje, Jonathan, Martens, Jos, Oomens, Jeroen D C, Codée
Publikováno v:
The Journal of organic chemistry. 87(14)
The stereoselective introduction of glycosidic bonds is of paramount importance to oligosaccharide synthesis. Among the various chemical strategies to steer stereoselectivity, participation by either neighboring or distal acyl groups is used particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2454ff73d093fa81a93c713693b4c8d
https://pubmed.ncbi.nlm.nih.gov/35748115
https://pubmed.ncbi.nlm.nih.gov/35748115
Autor:
Kas J. Houthuijs, Jonathan Martens, Giel Berden, Alexandra Arranja, J. Frank W. Nijsen, Jos Oomens
Publikováno v:
PCCP Physical Chemistry Chemical Physics, 22, pp. 15716-15722
Physical Chemistry Chemical Physics, 22(27), 15716-15722. Royal Society of Chemistry
PCCP Physical Chemistry Chemical Physics, 22, 15716-15722
Physical Chemistry Chemical Physics, 22(27), 15716-15722. Royal Society of Chemistry
PCCP Physical Chemistry Chemical Physics, 22, 15716-15722
Microspheres containing radioactive 166holmium-acetylacetonate are employed in emerging radionuclide therapies for the treatment of malignancies. At the molecular level, details on the coordination geometries of the Ho complexes are however elusive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9192853cd09490e30dad8ac90c1ef58a
https://doi.org/10.1039/d0cp01890b
https://doi.org/10.1039/d0cp01890b
Autor:
Wouter A. Remmerswaal, Kas J. Houthuijs, Roel van de Ven, Hidde Elferink, Thomas Hansen, Giel Berden, Herman S. Overkleeft, Gijsbert A. van der Marel, Floris P. J. T. Rutjes, Dmitri V. Filippov, Thomas J. Boltje, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée
Publikováno v:
Journal of Organic Chemistry (JOC), 87(14), 9139-9147. AMER CHEMICAL SOC
Journal of Organic Chemistry, 87, 9139-9147
Journal of Organic Chemistry, 87, 14, pp. 9139-9147
Remmerswaal, W A, Houthuijs, K J, Van De Ven, R, Elferink, H, Hansen, T, Berden, G, Overkleeft, H S, Van Der Marel, G A, Rutjes, F P J T, Filippov, D V, Boltje, T J, Martens, J, Oomens, J & Codée, J D C 2022, ' Stabilization of Glucosyl Dioxolenium Ions by "dual Participation" of the 2,2-Dimethyl-2-(ortho-nitrophenyl)acetyl (DMNPA) Protection Group for 1,2-cis-Glucosylation ', Journal of Organic Chemistry, vol. 87, no. 14, pp. 9139-9147 . https://doi.org/10.1021/acs.joc.2c00808
Journal of Organic Chemistry, 87(14), 9139-9147. American Chemical Society
Journal of Organic Chemistry, 87, 9139-9147
Journal of Organic Chemistry, 87, 14, pp. 9139-9147
Remmerswaal, W A, Houthuijs, K J, Van De Ven, R, Elferink, H, Hansen, T, Berden, G, Overkleeft, H S, Van Der Marel, G A, Rutjes, F P J T, Filippov, D V, Boltje, T J, Martens, J, Oomens, J & Codée, J D C 2022, ' Stabilization of Glucosyl Dioxolenium Ions by "dual Participation" of the 2,2-Dimethyl-2-(ortho-nitrophenyl)acetyl (DMNPA) Protection Group for 1,2-cis-Glucosylation ', Journal of Organic Chemistry, vol. 87, no. 14, pp. 9139-9147 . https://doi.org/10.1021/acs.joc.2c00808
Journal of Organic Chemistry, 87(14), 9139-9147. American Chemical Society
The stereoselective introduction of glycosidic bonds is of paramount importance to oligosaccharide synthesis. Among the various chemical strategies to steer stereoselectivity, participation by either neighboring or distal acyl groups is used particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a58321247d741426ba6183eca07e93
https://doi.org/10.1021/acs.joc.2c00808
https://doi.org/10.1021/acs.joc.2c00808