Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karynn Veillette"'
Autor:
Deming Xu, Bo Jiang, Troy Ketela, Sebastien Lemieux, Karynn Veillette, Nick Martel, John Davison, Susan Sillaots, Steve Trosok, Catherine Bachewich, Howard Bussey, Phil Youngman, Terry Roemer
Publikováno v:
PLoS Pathogens, Vol 3, Iss 6, p e92 (2007)
Candida albicans is a prevalent fungal pathogen amongst the immunocompromised population, causing both superficial and life-threatening infections. Since C. albicans is diploid, classical transmission genetics can not be performed to study specific a
Externí odkaz:
https://doaj.org/article/2d4d101ed40342ab938de2496b3ec007
Autor:
Fatou Tandia, John Davison, Reginald Storms, Anouk Breton, Nick Martel, Jeff Becker, Karynn Veillette, Sébastien Lemieux, Troy Ketela, Susan Sillaots, Annie Linteau, Catarina Marta, Howard Bussey, Terry Roemer, Bo Jiang, Charles Boone, Steeve Veronneau, Sarah Kauffman
Publikováno v:
Molecular Microbiology. 50:167-181
Summary Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs to combat fungal infections [Sobel, J.D. (2000) Clin Infectious Dis 30: 652], antifungal drug discovery is currently limited by both the availability
Autor:
John Davison, Bo Jiang, Charles E. Martin, Li Zhang, Pam Ocampo, Minghui Yang, Steve Trosok, Nick Martel, Hao Wang, Sarah Kauffman, Wenqi Hu, Terry Roemer, Deming Xu, Chan-Seok Oh, Susan Sillaots, Jeffrey M. Becker, Karynn Veillette
Publikováno v:
The Journal of biological chemistry. 284(29)
The balance between saturated and unsaturated fatty acids plays a crucial role in determining the membrane fluidity. In the diploid fungal pathogen Candida albicans, the gene for fatty acid Delta9 desaturase, OLE1, is essential for viability. Using a
Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans
Autor:
Karynn Veillette, Howard Bussey, Nick Martel, John Davison, Deming Xu, Susan Sillaots, Troy Ketela, Bo Jiang, Terry Roemer, Sébastien Lemieux, Phil Youngman, Catherine Bachewich, Steve Trosok
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 3, Iss 6, p e92 (2007)
PLoS Pathogens, Vol 3, Iss 6, p e92 (2007)
Candida albicans is a prevalent fungal pathogen amongst the immunocompromised population, causing both superficial and life-threatening infections. Since C. albicans is diploid, classical transmission genetics can not be performed to study specific a
Autor:
Robert A. Giacobbe, Yang Li, Tara Ransom, Gonzalo Platas, Bo Jiang, Douglas Wisniewski, Fariba Rahkhoodaee, Amy M. Flattery, Roberto Rodriguez-Suarez, Phil Youngman, Kenneth E. Wilson, Scott P. Salowe, Jennifer Nielsen Kahn, Gerald F. Bills, Terry Roemer, Hao Wang, Nick Martel, Ming Jo Hsu, Steve Trosok, Judyann Wiltsie, Maria Teresa Diez, Daniel Gauvin, Paul A. Liberator, Guy H. Harris, Craig A. Parish, Susan Sillaots, John J. Allocco, Sarah Kauffman, John Davison, Karynn Veillette, Li Zhang, Wenqi Hu, Fernando Pelaez, Jeff Becker, Deming Xu, George K. Abruzzo, Charles Gill
Publikováno v:
Chemistry & Biology. (4):363-374
SummaryNatural products provide an unparalleled source of chemical scaffolds with diverse biological activities and have profoundly impacted antimicrobial drug discovery. To further explore the full potential of their chemical diversity, we survey na