Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Karyn J Catalano"'
Autor:
Orison O Woolcott, Joyce M Richey, Morvarid Kabir, Robert H Chow, Malini S Iyer, Erlinda L Kirkman, Darko Stefanovski, Maya Lottati, Stella P Kim, L Nicole Harrison, Viorica Ionut, Dan Zheng, Isabel R Hsu, Karyn J Catalano, Jenny D Chiu, Heather Bradshaw, Qiang Wu, Cathryn M Kolka, Richard N Bergman
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131033 (2015)
Externí odkaz:
https://doaj.org/article/acd325e4dfb44e77824615af03a18330
Autor:
Orison O Woolcott, Joyce M Richey, Morvarid Kabir, Robert H Chow, Malini S Iyer, Erlinda L Kirkman, Darko Stefanovski, Maya Lottati, Stella P Kim, L Nicole Harrison, Viorica Ionut, Dan Zheng, Isabel R Hsu, Karyn J Catalano, Jenny D Chiu, Heather Bradshaw, Qiang Wu, Cathryn M Kolka, Richard N Bergman
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123558 (2015)
BACKGROUND:Obesity has been associated with elevated plasma anandamide levels. In addition, anandamide has been shown to stimulate insulin secretion in vitro, suggesting that anandamide might be linked to hyperinsulinemia. OBJECTIVE:To determine whet
Externí odkaz:
https://doaj.org/article/a9550449b61140ec87d3e78492fae4f0
Autor:
Karyn J Catalano, Betty A Maddux, Jaroslaw Szary, Jack F Youngren, Ira D Goldfine, Fred Schaufele
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108693 (2014)
Insulin resistance, the diminished response of target tissues to insulin, is associated with the metabolic syndrome and a predisposition towards diabetes in a growing proportion of the worldwide population. Under insulin resistant states, the cellula
Externí odkaz:
https://doaj.org/article/bf22db14a9dd4d499ca8c8f1c234c00c
Autor:
Jennifer Lee, Kerry Wellenstein, Jacqueline Lynch, Karyn J. Catalano, Abha Dhaneshwar, Benjamin G. Neel, Alexandra Sontheimer, Odile D. Peroni, Barbara B. Kahn, Franck Chiappini
Publikováno v:
Journal of Clinical Investigation. 124:3781-3792
Protein-tyrosine phosphatase 1B (PTP1B) regulates food intake (FI) and energy expenditure (EE) by inhibiting leptin signaling in the hypothalamus. In peripheral tissues, PTP1B regulates insulin signaling, but its effects on CNS insulin action are lar
Autor:
Darko Stefanovski, Vahe Mooradian, Karyn J. Catalano, Jenny D. Chiu, Stella P. Kim, Justin Dittmann, Dan Zheng, Orison O. Woolcott, Morvarid Kabir, Cathryn M. Kolka, Richard N. Bergman, Gregg W. Van Citters, Sophia Yae, Maya Lottati, Marilyn Ader, Viorica Ionut, Lisa N. Harrison, Huiwen Liu, Katrin Hücking, Joyce M. Richey, Isabel R. Hsu, Martin Ellmerer, Ana Valeria B. Castro
Publikováno v:
Obesity. 22:1238-1245
Objective Insulin resistance is a powerful risk factor for Type 2 diabetes and a constellation of chronic diseases, and is most commonly associated with obesity. We examined if factors other than obesity are more substantial predictors of insulin sen
Autor:
Dan Zheng, Richard N. Bergman, Orison O. Woolcott, Viorica Ionut, Maya Lottati, Darko Stefanoski, Isabel R. Hsu, Morvarid Kabir, Stella P. Kim, Karyn J. Catalano, L. Nicole Harrison, Cathryn M. Kolka, Joyce M. Richey, Jenny D. Chiu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 302:E1261-E1268
The endocannabinoid system is highly implicated in the development of insulin resistance associated with obesity. It has been shown that antagonism of the CB1 receptor improves insulin sensitivity (SI). However, it is unknown whether this improvement
Publikováno v:
Diabetes
OBJECTIVE Age-associated insulin resistance may be caused by increased visceral adiposity and older animals appear to be more susceptible to obesity-related resistance than young animals. However, it is unclear to what extent the portally drained mes
Autor:
Noboru Furukawa, Incoronata Murano, Yasuhiko Minokoshi, Mirela Delibegovic, Karyn J. Catalano, James A. Balschi, Bingzhong Xue, Anna Lee, Thomas Pulinilkunnil, Kendra K. Bence, Kenji Asakura, Huamei He, Benjamin G. Neel, Barbara B. Kahn, Saverio Cinti, Fawaz G. Haj
Publikováno v:
Molecular and Cellular Biology. 29:4563-4573
PTP1B(-/-) mice are resistant to diet-induced obesity due to leptin hypersensitivity and consequent increased energy expenditure. We aimed to determine the cellular mechanisms underlying this metabolic state. AMPK is an important mediator of leptin's
Autor:
L. Nicole Harrison, Morvarid Kabir, Darko Stefanovski, Richard N. Bergman, Orison O. Woolcott, Cathryn M. Kolka, Dan Zheng, Viorica Ionut, Vahe Mooradian, Isabel R. Hsu, Stella P. Kim, Maya Lottati, Joyce M. Richey, Karyn J. Catalano, Jenny D. Chiu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 296:E1311-E1318
We investigated whether rimonabant, a type 1 cannabinoid receptor antagonist, reduces visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in dogs maintained on a hypercaloric high-fat diet (HHFD). To determine whether energy expenditu
Autor:
Stella P. Kim, Richard N. Bergman, Marilyn Ader, Jenny D. Chiu, Joyce M. Richey, Isabel R. Hsu, Morvarid Kabir, Karyn J. Catalano
Publikováno v:
The American Journal of Medicine. 120:S3-S8
Visceral adiposity has been identified as an independent risk factor for cardiovascular disease and the so-called metabolic syndrome. The canine obesity model closely recapitulates the correlation between human visceral adiposity and insulin resistan