Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karyn Colman"'
Autor:
Brad Bolon, Sabine Francke, Jessica M. Caverly Rae, Evelyne Polack, Karen S. Regan, Elizabeth F. McInnes, Jamie K. Young, Kevin Keane, Rick Perry, Annette Romeike, Karyn Colman, Karl Jensen, Kyoko Nakano-Ito, Elizabeth J. Galbreath
Publikováno v:
Toxicologic pathology. 50(8)
This article describes the Society of Toxicologic Pathology’s (STP) five recommended (“best”) practices for appropriate use of informed (non-blinded) versus masked (blinded) microscopic evaluation in animal toxicity studies intended for regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de9dc26cd7c988521940b0bd21e36a9
https://pubmed.ncbi.nlm.nih.gov/36377245
https://pubmed.ncbi.nlm.nih.gov/36377245
Autor:
Michael S. Thibodeau, Manoj Bhaskaran, Aleksandra Zalewska, Balasubramanian Manickam, Justin D. Vidal, Jonathan Werner, Wendy G. Halpern, Karyn Colman, Sean McKeag, Benjamin Sefing, Darren Fegley, Karen S. Regan, Binod Jacob, Eveline de Rijk, Vimala Vemireddi, George A. Parker, Hitoshi Kandori
Publikováno v:
Toxicologic Pathology. 49:977-989
The sexual maturity status of animals in nonclinical safety studies can have a significant impact on the microscopic assessment of the reproductive system, the interpretation of potential test article–related findings, and ultimately the assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b875dc51afa16eb8629752f0d10e9768
https://doi.org/10.1177/0192623321990631
https://doi.org/10.1177/0192623321990631
Autor:
Radhakrishna Sura, Jonathan Werner, Molly H. Boyle, Christopher Houle, Begonya Garcia, Bindu Bennet, Annette Romeike, Karyn Colman, Anna-Lena Frisk, Susan A. Elmore
Publikováno v:
Toxicol Pathol
Toxicologic Pathology is the official journal of the Society of Toxicologic Pathology (STP), the British Society of Toxicological Pathology (BSTP), and the European Society of Toxicologic Pathology (ESTP). Toxicologic Pathology publishes articles rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fda5fe770e72e941c75c7c39e68ea6
https://doi.org/10.1177/0192623321992305
https://doi.org/10.1177/0192623321992305
Autor:
Graham Paul, Stuart W. Naylor, Nicholas P. Macri, Scott Manetz, Richard Haworth, A. Peter Hall, David Jones, Thierry Flandre, Jeffrey S. Tepper, Michela Gregori, Annick Cauvin, Molly H. Boyle, Sydney Mukaratirwa, Alison Wolfreys, Renaud Fleurance, Inge Tarnow, Kristen J. Nikula, Alessandro Piaia, Mark Price, Ian Robinson, Andrew Allen, Tom Gelzleichter, Mark C Freke, Karyn Colman, Andreas M Hohlbaum, Maurice G Cary
Publikováno v:
Toxicologic Pathology. 49:235-260
The inhalation route is a relatively novel drug delivery route for biotherapeutics and, as a result, there is a paucity of published data and experience within the toxicology/pathology community. In recent years, findings arising in toxicology studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507bdc0e870c9ffe85569d58c5326be1
https://doi.org/10.1177/0192623320976094
https://doi.org/10.1177/0192623320976094
Autor:
Jochen Woicke, Muthafar M. Al-Haddawi, Jean-Guy Bienvenu, Jessica M. Caverly Rae, Franck J. Chanut, Karyn Colman, John M. Cullen, Wendell Davis, Ryo Fukuda, Maike Huisinga, Ursula Junker Walker, Kiyonori Kai, Ramesh C. Kovi, Nicholas P. Macri, Heike-Antje Marxfeld, Kristen J. Nikula, Ingrid D. Pardo, Thomas J. Rosol, Alok K. Sharma, Bhanu P. Singh, Kazutoshi Tamura, Michael S. Thibodeau, Enrico Vezzali, Justin D. Vidal, Emily K. Meseck
Publikováno v:
Toxicologic Pathology. 49:5-109
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions) Project ( www.toxpath.org/inhand.asp ) is a joint initiative of the societies of toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6c7853ca62350eb8e995507fa8b2e2
https://doi.org/10.1177/0192623320968181
https://doi.org/10.1177/0192623320968181
Autor:
Jeremy L. Jenkins, Katrin Volkmann, Shelly Meeusen, Prisca Liberali, Karyn Colman, Ludivine Challet Meylan, Michael B. Stadler, Ilya Lukonin, Janine E. Baaten, Denise Serra, Rui Zhao, Francisca Maurer
Publikováno v:
Nature
The development of intestinal organoids from single adult intestinal stem cells in vitro recapitulates the regenerative capacity of the intestinal epithelium1,2. Here we unravel the mechanisms that orchestrate both organoid formation and the regenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef2914c3fb4511271adaf18a1eeeef
https://doi.org/10.1038/s41586-020-2776-9
https://doi.org/10.1038/s41586-020-2776-9
Autor:
Bo Liu, Sukwon Ha, H. Michael Petrassi, Kate Jacobsen, George Harb, W. Perry Gordon, Bryan Laffitte, Thanh Lam, Qihui Jin, Yong Jia, Janine E. Baaten, Minhua Qiu, Robert Hill, Shelly Meeusen, Shanshan Yan, Badry Bursulaya, Valentina Molteni, Anwesh Kamireddy, Lisa Deaton, Jianfeng Pan, You-Qing Zhang, Loren Jon, Michael DiDonato, Yahu A. Liu, Shifeng Pan, Andrew M. Schumacher, Tingting Mo, Yefen Zou, Xiaoyue Zhang, Weijun Shen, Karyn Colman, Richard Glynne, Xueshi Hao, Peter McNamara, Vân Nguyen-Tran, Zhicheng Wang, Sheryll Espinola, Bao Nguyen, Tom Y.-H. Wu, Jing Li, Qiang Ding
Publikováno v:
Journal of Medicinal Chemistry. 63:2958-2973
Autoimmune deficiency and destruction in either β-cell mass or function can cause insufficient insulin levels and, as a result, hyperglycemia and diabetes. Thus, promoting β-cell proliferation could be one approach toward diabetes intervention. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e5ae5085b8fd7b08c90167919a793
https://doi.org/10.1021/acs.jmedchem.9b01624
https://doi.org/10.1021/acs.jmedchem.9b01624
Autor:
Karyn, Colman, Rachel N, Andrews, Hannah, Atkins, Theresa, Boulineau, Alys, Bradley, Annamaria, Braendli-Baiocco, Raffaella, Capobianco, David, Caudell, Mark, Cline, Takuya, Doi, Rainer, Ernst, Eric, van Esch, Jeffrey, Everitt, Pierluigi, Fant, Margarita M, Gruebbel, Lars, Mecklenburg, Andew D, Miller, Kristen J, Nikula, Shigeru, Satake, Julie, Schwartz, Alok, Sharma, Akihito, Shimoi, Cécile, Sobry, Ian, Taylor, Vimala, Vemireddi, Justin, Vidal, Charles, Wood, John L, Vahle
Publikováno v:
Journal of Toxicologic Pathology
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e526dcfd7f7a5de8fc7b019878f90472
https://pubmed.ncbi.nlm.nih.gov/34712008
https://pubmed.ncbi.nlm.nih.gov/34712008
Publikováno v:
Toxicologic pathology. 49(2)
The delivery of biotherapeutic molecules (antibodies, proteins, peptides) and nucleic acids via the respiratory route has presented challenges for regulatory approval, due in part to a lack of understanding of the expected pathology, mechanisms of to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a2def2a517c0bd057d29bd367322d1
https://pubmed.ncbi.nlm.nih.gov/33397211
https://pubmed.ncbi.nlm.nih.gov/33397211
Autor:
Frank D. Sistare, Raja Mangipudy, Diann Blanset, Karyn Colman, Matthew S. Bogdanffy, David Garcia-Tapia, Thomas M. Monticello, Jacob Lesniak
Publikováno v:
International journal of toxicology. 39(3)
The Tg.rasH2 mouse was developed as an alternative model to the traditional 2-year mouse bioassay for pharmaceutical carcinogenicity testing. This model has found extensive use in support of pharmaceutical drug development over the last few decades.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6212451347521b319744728a1a42c1
https://pubmed.ncbi.nlm.nih.gov/32372678
https://pubmed.ncbi.nlm.nih.gov/32372678