Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.

Autor: McDonnell MM; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America.; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., Karvonen SC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., Gaba A; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Flath B; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Chelico L; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Emerman M; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Jun 25; Vol. 17 (6), pp. e1009523. Date of Electronic Publication: 2021 Jun 25 (Print Publication: 2021).