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pro vyhledávání: '"Karunakar Saamarthy"'
Autor:
Ganesh Acharya, Chinnadurai Mani, Naresh Sah, Karunakar Saamarthy, Robert Young, Mark B. Reedy, Robert W. Sobol, Komaraiah Palle
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Chemoresistance contributes to the majority of deaths in women with ovarian cancer (OC). Altered DNA repair and metabolic signaling is implicated in mediating therapeutic resistance. DNA damage checkpoint kinase 1 (CHK1) integrates cell cycl
Externí odkaz:
https://doaj.org/article/fc36ae4b6fdf4aff9425053db2638baa
Autor:
Karunakar Saamarthy, Kristofer Ahlqvist, Renée Daams, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis, Julhash U. Kazi, Wondossen Sime, Ramin Massoumi
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a specific protein is a foundation of precision medicine and treatment. High expression of the proto-oncogene Bcl-3 promotes the
Externí odkaz:
https://doaj.org/article/6b80a0ad3a0047ca8c7f56a2224e0c1d
Autor:
Chinnadurai Mani, Ganesh Acharya, Karunakar Saamarthy, Damieanus Ochola, Srinidhi Mereddy, Kevin Pruitt, Upender Manne, Komaraiah Palle
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-122 (2023)
Abstract Background Triple-negative breast cancer (TNBC) affects young women and is the most aggressive subtype of breast cancer (BC). TNBCs disproportionally affect women of African-American (AA) descent compared to other ethnicities. We have identi
Externí odkaz:
https://doaj.org/article/80b5a021020f418ba0bea9ee518b191e
Publikováno v:
Oncogene
B-cell leukemia 3 (Bcl-3) is a member of the inhibitor of κB family, which regulates a wide range of biological processes by functioning as a transcriptional activator or as a repressor of target genes. As high levels of Bcl-3 expression and activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c34da7f0e31fce7a398a024a7a8e36
https://doi.org/10.1038/onc.2012.175
https://doi.org/10.1038/onc.2012.175
Autor:
Olof P. Persson, Simon Tuck, Jörgen Stenvall, Qing Cheng, Briseida Cacho-Valadez, Peter Swoboda, Antonio Miranda-Vizuete, Juan Carlos Fierro-González, Karunakar Saamarthy, Elias S.J. Arnér
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Proceedings of the National Academy of Sciences
instname
Proceedings of the National Academy of Sciences
6 páginas, 5 figuras.-- et al.
Selenoproteins, in particular thioredoxin reductase, have been implicated in countering oxidative damage occurring during aging but the molecular functions of these proteins have not been extensively investigated
Selenoproteins, in particular thioredoxin reductase, have been implicated in countering oxidative damage occurring during aging but the molecular functions of these proteins have not been extensively investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81ec47e1ee8cf67a2546d4a48c13221
http://hdl.handle.net/10261/38909
http://hdl.handle.net/10261/38909
Autor:
Karunakar Saamarthy, Ramin Massoumi, Sofie Björner, Katarzyna Chmielarska Masoumi, Göran Landberg, Martin Johansson, Karin Jirström
Publikováno v:
BMC Cancer; 15(1), no 341 (2015)
BMC Cancer
BMC Cancer
Background B-cell leukemia 3 (Bcl-3) is a member of the inhibitor of κB family, which regulates a wide range of biological processes by functioning as a transcriptional activator or as a repressor of target genes. Elevated expression, sustained nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b865054bd1aab7da1c11aba0cafe5e22