Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karuna, Adhikari"'
Autor:
Louis Lauwerys, Lucas Beroske, Angelo Solania, Christel Vangestel, Alan Miranda, Nele Van Giel, Karuna Adhikari, Anne-Marie Lambeir, Leonie wyffels, Dennis Wolan, Pieter Van der Veken, Filipe Elvas
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-26 (2024)
Abstract Background The cysteine-aspartic acid protease caspase-3 is recognized as the main executioner of apoptosis in cells responding to specific extrinsic and intrinsic stimuli. Caspase-3 represents an interesting biomarker to evaluate treatment
Externí odkaz:
https://doaj.org/article/7d195dcb92624a9bab00b7cbe35e7adc
Autor:
Karuna Adhikari, Maarten Vanermen, Gustavo Da Silva, Tim Van den Wyngaert, Koen Augustyns, Filipe Elvas
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-56 (2024)
Abstract Background Trans-cyclooctenes (TCOs) are highly strained alkenes with remarkable reactivity towards tetrazines (Tzs) in inverse electron-demand Diels–Alder reactions. Since their discovery as bioorthogonal reaction partners, novel TCO deri
Externí odkaz:
https://doaj.org/article/2f2c94c1235e40a6b6b11ce4f6ed7def
Autor:
Karuna Adhikari, Jonatan Dewulf, Christel Vangestel, Pieter Van der Veken, Sigrid Stroobants, Filipe Elvas, Koen Augustyns
Publikováno v:
ACS Omega, Vol 8, Iss 41, Pp 38252-38262 (2023)
Externí odkaz:
https://doaj.org/article/eb3942f162174473a450163bce286f3a
Autor:
Eduardo Ruivo, Filipe Elvas, Karuna Adhikari, Christel Vangestel, Glenn Van Haesendonck, Filip Lemière, Steven Staelens, Sigrid Stroobants, Pieter Van der Veken, Leonie wyffels, Koen Augustyns
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4449-4456 (2020)
Externí odkaz:
https://doaj.org/article/67db9c5384724660a66407972f59779d
Autor:
Teppo O. Leino, Ainoleena Turku, Lauri Urvas, Karuna Adhikari, Jouni Oksanen, Yana Steynen, Jari Yli-Kauhaluoma, Henri Xhaard, Jyrki P. Kukkonen, Erik A.A. Wallén
Azulene is a rare ring structure in drugs, and we investigated whether it could be used as a biphenyl mimetic in known orexin receptor agonist Nag 26, which is binding to both orexin receptors OX1 and OX2 with preference towards OX2. The most potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7df09711b7611d8344b9ac76de0bc4c
http://hdl.handle.net/10138/359559
http://hdl.handle.net/10138/359559
Autor:
Jens Fissers, Filipe Elvas, Steven Staelens, Christel Vangestel, Karuna Adhikari, Koen Augustyns, Eduardo Ruivo, Leonie Wyffels, Pieter Van der Veken, Sigrid Stroobants
Publikováno v:
Nuclear medicine and biology
Introduction: Biorthogonal pretargeted imaging using the inverse electron demand Diels Alder (IEDDA) reaction between tetrazine (Tz) and trans-cyclooctene (TCO) is one of the most attractive strategies in molecular imaging. It allows the use of short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21af79af795620d5c9700ca9bd823873
https://doi.org/10.1016/j.nucmedbio.2019.11.001
https://doi.org/10.1016/j.nucmedbio.2019.11.001
Publikováno v:
Nuclear Medicine and Biology. :S176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bfba17a605854248b57ee23d1053080
https://doi.org/10.1016/s0969-8051(22)00370-5
https://doi.org/10.1016/s0969-8051(22)00370-5
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1868, p 1868 (2020)
Cancers, Vol 12, Iss 1868, p 1868 (2020)
Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are molecular imaging strategies that typically use radioactively labeled ligands to selectively visualize molecular targets. The nanomolar sensitivity of PET a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea33a2c04d8e74964d84f779583d2d8
http://europepmc.org/articles/PMC7408676
http://europepmc.org/articles/PMC7408676
Autor:
Eduardo, Ruivo, Filipe, Elvas, Karuna, Adhikari, Christel, Vangestel, Glenn, Van Haesendonck, Filip, Lemière, Steven, Staelens, Sigrid, Stroobants, Pieter, Van der Veken, Leonie, Wyffels, Koen, Augustyns
Publikováno v:
ACS Omega
Pretargeted positron emission tomography (PET) imaging based on the bioorthogonal inverse-electron-demand Diels–Alder reaction between tetrazines (Tz) and trans-cyclooctenes (TCO) has emerged as a promising tool for solid tumor imaging, allowing th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dae10aa0da6bdf96ecdbadbe21573860
https://pubmed.ncbi.nlm.nih.gov/32175492
https://pubmed.ncbi.nlm.nih.gov/32175492