Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Karun Tandon"'
Autor:
Spencer Revill, Pierre-Simon Bellaye, Martin Kolb, Karun Tandon, Kjetil Ask, Nathan Hambly, Ehab A. Ayaub, Jean-Claude Cutz, Philipp Kolb, Asghar Naqvi, Tamana Yousof, Martha M. Vaughan, Jiro Kato, Safaa Naiel, Megan Vierhout, Soumeya Abed, Anmar Ayoub, Joel Moss, Manreet Padwal, Anna Dvorkin-Gheva, Victor Tat, Olivia Mekhael
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 64:235-246
Pulmonary fibrosis is a progressive lung disease characterized by myofibroblast accumulation and excessive extracellular matrix deposition. Endoplasmic reticulum (ER) stress initiates the unfolded protein response (UPR), a cellular stress response pa
Autor:
Anmar Ayoub, Šárka Lhoták, Ehab A. Ayaub, Anna Dvorkin-Gheva, Manreet Padwal, Chandak Upagupta, Philipp Kolb, Kjetil Ask, James Murphy, Martin Kolb, Richard C. Austin, Carl D. Richards, Hemisha Patel, Jewel Imani, Anisha Dubey, Karun Tandon, Olivia Mekhael, Jeffrey G. Dickhout
Publikováno v:
Immunology and Cell Biology
Although recent evidence has shown that IL‐6 is involved in enhanced alternative activation of macrophages toward a profibrotic phenotype, the mechanisms leading to their increased secretory capacity are not fully understood. Here, we investigated
Autor:
Kjetil Ask, Mark Jones, James Roberts, Victoria Tear, Kerry Lunn, Martin Kolb, James Murphy, Donna E. Davies, Lucy Cao, Jack Gauldie, Chiko Shimbori, Phillip Monk, Karun Tandon, Wolfgang Jarolimek, Jewel Imani, Ehab A. Ayaub
Publikováno v:
Mechanisms of Lung Injury and Repair.
Background: Increased tissue stiffness is a consequence and a driver of fibrosis. Tissue stiffness is modulated by the lysyl oxidase (LOX) family of enzymes, which cross-link collagen and elastin fibres. Increased expression of LOX-like-2 (LOXL2) is
Autor:
Carl D. Richards, Chandak Upagupta, Pavithra Parthasarathy, James Murphy, Jewel Imani, Kjetil Ask, Martin Kolb, Anisha Dubey, Mark D. Inman, Karun Tandon, Ehab A. Ayaub
Publikováno v:
QJM: An International Journal of Medicine.